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Publications van den Anker Johannes

Clinical utiliy of a model-based piperacillin dose in neonates with early-onset sepsis.

Wu YE; Hou SS; Fang ZY; Tang BH; Yao BF; Dong YN; Li X; Shi HY; Zheng Y; Hao GX; Huang X; Van Den Anker J; Yu YH; Zhao W. British Journal of Clinical Pharmacology. 2022.

Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.

Smits A; Annaert P; Cavallaro G; De Cock PAJG; de Wildt SN; Kindblom JM; Lagler FB; Moreno C; Pokorna P; Schreuder MF; Standing JF; Turner MA; Vitiello B; Zhao W; Weingberg AM; Willmann R; van den Anker J; Allegaert K. British Journal of Clinical Pharmacology. 2022.

Novel strategy to personalise use of ibuprofen for closure of patent ductus arteriosus in preterm neonates.

Samiee-Zafarghandy S; van Donge T; Fusch G; Pfister M; Jacob G; Atkinson A; Rieder MJ; Smit C; Van Den Anker J. Archives of Disease in Childhood. 2022.

Population Pharmacokinetics and Safety of Dasatinib in Chinese Children with Core-Binding Factor Acute Myeloid Leukemia.

Yang F; Zhang L; Zhao BB; Zhang JL; Liu XT; Li X; Tang BH; Zhou Y; Yang XM; van den Anker J; Zhu XF; Zhao W. Clinical Pharmacokinetics. 2022.

Therapeutic Drug Monitoring of Antimicrobial Drugs in Neonates: An Opinion Article.

Touw DJ; van den Anker JN. Therapeutic drug monitoring. 2022.

Adolescents and Drug Development: Commentary on a Dawning Paradigm Shift.

Kearns GL; van den Anker JN. Journal of Clinical Pharmacology. 2021.

Amikacin or Vancomycin Exposure Alters the Postnatal Serum Creatinine Dynamics in Extreme Low Birth Weight Neonates.

van Donge T; Smits A; van den Anker J; Allegaert K. International Journal of Environmental Research and Public Health. 2021.

Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery.

Miszta A; Ahmadzia HK; Luban NLC; Li S; Guo D; Holle LA; Berger JS; James AH; Gobburu JVS; van den Anker J; de Laat B; Wolberg AS. Journal of Thrombosis and Haemostasis. 2021.

A simplified method for bortezomib determination using dried blood spots in combination with liquid chromatography/tandem mass spectrometry.

Guo ZX; Yang F; van den Anker JN; Zheng Y; Zhao W. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2021.

Challenges in conducting paediatric trials with off-patent drugs.

Haslund-Krog SS; Jorgensen IM; Henriksen TB; Dalhoff K; Debes NM; van den Anker J; Holst H. Contemporary clinical trials communications. 2021.

Characterizing dynamics of serum creatinine and creatinine clearance in extremely low birth weight neonates during the first 6 weeks of life.

van Donge T; Allegaert K; Gotta V; Smits A; Levtchenko E; Mekahli D; van den Anker J; Pfister M. Pediatric Nephrology. 2021.

Considerations for Drug Dosing in Premature Infants.

van den Anker J; Allegaert K. Journal of Clinical Pharmacology. 2021.

Corrigendum to: Age appropriate reference intervals for eight kidney function and injury markers in infants, children and adolescents.

van Donge T; Staub E; Atkinson A; Gotta V; van den Anker J; Risch L; Welzel T; Pfister M. . 2021.

COVID-19 in Autoinflammatory Diseases with Immunosuppressive Treatment.

Welzel T; Samba SD; Klein R; van den Anker JN; Kuemmerle-Deschner JB. Journal of Clinical Medicine. 2021.

Creatinine at Birth Correlates with Gestational Age and Birth Weight: Another Factor of the Imbroglio in Early Neonatal Life

Allegaert K.; Smits A.; Mekahli D.; Van Den Anker J.N.. Neonatology. 2021.

Dose-Related Adverse Drug Events in Neonates: Recognition and Assessment.

Allegaert K; van den Anker J. Journal of Clinical Pharmacology. 2021.

Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction.

Tang BH; Guan Z; Allegaert K; Wu YE; Manolis E; Leroux S; Yao BF; Shi HY; Li X; Huang X; Wang WQ; Shen AD; Wang XL; Wang TY; Kou C; Xu HY; Zhou Y; Zheng Y; Hao GX; Xu BP; Thomson AH; Capparelli EV; Biran V; Simon N; Meibohm B; Lo YL; Marques R; Peris JE; Lutsar I; Saito J; Burggraaf J; Jacqz-Aigrain E; van den Anker J; Zhao W. Clinical Pharmacokinetics. 2021.

Drug-drug and drug-food interactions in an infant with early-onset SCN2A epilepsy treated with carbamazepine, phenytoin and a ketogenic diet.

Welzel T; Ziesenitz VC; Weber P; Datta AN; van den Anker JN; Gotta V. British Journal of Clinical Pharmacology. 2021.

Editorial: Model-Based Evaluation of Antimicrobial Agents in Children.

Zhao W; Wu YE; van den Anker J. . 2021.

Effect of Genetic Variation in CYP450 on Gonadal Impairment in a European Cohort of Female Childhood Cancer Survivors, Based on a Candidate Gene Approach: Results from the PanCareLIFE Study.

van der Perk MEM; Broer L; Yasui Y; Robison LL; Hudson MM; Laven JSE; van der Pal HJ; Tissing WJE; Versluys B; Bresters D; Kaspers GJL; de Vries ACH; Lambalk CB; Overbeek A; Loonen JJ; Beerendonk CCM; Byrne J; Berger C; Clemens E; Dirksen U; Falck Winther J; Fosså SD; Grabow D; Muraca M; Kaiser M; Kepák T; Kruseova J; Modan-Moses D; Spix C; Zolk O; Kaatsch P; Krijthe JH; Kremer LCM; Brooke RJ; Baedke JL; van Schaik RHN; van den Anker JN; Uitterlinden AG; Bos AME; van Leeuwen FE; van Dulmen-den Broeder E; van der Kooi ALF; van den Heuvel-Eibrink MM; On Behalf Of The PanCareLIFE Consortium. Cancers. 2021.

Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy.

Benny Klimek ME; Vila MC; Edwards K; Boehler J; Novak J; Zhang A; Van der Meulen J; Tatum K; Quinn J; Fiorillo A; Burki U; Straub V; Lu QL; Hathout Y; van Den Anker J; Partridge TA; Morales M; Hoffman E; Nagaraju K. Journal of neuromuscular diseases. 2021.

Efficacy and safety of vasopressin and terlipressin in preterm neonates: a protocol for a systematic review.

Alsaadi AS; Sushko K; Bui V; Van Den Anker J; Razak A; Samiee-Zafarghandy S. . 2021.

Evaluation of Physiologically Based Pharmacokinetic Models to Predict the Absorption of BCS Class I Drugs in Different Pediatric Age Groups.

Liu XI; van den Anker JN; Burckart GJ; Dallmann A. Journal of Clinical Pharmacology. 2021.

Intrauterine Growth Retardation in Pregnant Women with Long QT Syndrome Treated with Beta-Receptor Blockers.

Welzel T; Donner B; van den Anker JN. Neonatology. 2021.

Is it time to replace morphine with methadone for the treatment of pain in the neonatal intensive care unit?

van den Anker J. Pediatric Research. 2021.

IV and oral fosfomycin pharmacokinetics in neonates with suspected clinical sepsis.

Kane Z; Gastine S; Obiero C; Williams P; Murunga S; Thitiri J; Ellis S; Correia E; Nyaoke B; Kipper K; van den Anker J; Sharland M; Berkley JA; Standing JF. Journal of Antimicrobial Chemotherapy. 2021.

LPS-Induced Inflammation Affects Midazolam Clearance in Juvenile Mice in an Age-Dependent Manner.

Zheng Y; Ye PP; Zhou Y; Wu SY; Liu XT; Du B; Tang BH; Kan M; Nie AQ; Yin R; Wang M; Hao GX; Song LL; Yang XM; Huang X; Su LQ; Wang WQ; van den Anker J; Zhao W. Journal of inflammation research. 2021.

Maternal paracetamol intake and fetal ductus arteriosus closure: adding pieces to the scenery.

Allegaert K; Ceulemans M; van den Anker J. . 2021.

Mechanistic Coupling of a Novel in silico Cotyledon Perfusion Model and a Physiologically Based Pharmacokinetic Model to Predict Fetal Acetaminophen Pharmacokinetics at Delivery.

Mian P; Nolan B; van den Anker JN; van Calsteren K; Allegaert K; Lakhi N; Dallmann A. Frontiers in Pediatrics. 2021.

Mechanistic Modeling of Placental Drug Transfer in Humans: How Do Differences in Maternal/Fetal Fraction of Unbound Drug and Placental Influx/Efflux Transfer Rates Affect Fetal Pharmacokinetics?

Liu X.I.; Green D.J.; van den Anker J.N.; Rakhmanina N.Y.; Ahmadzia H.K.; Momper J.D.; Park K.; Burckart G.J.; Dallmann A.. Frontiers in Pediatrics. 2021.

Monitoring the recovery time of children after tonsillectomy using commercial activity trackers.

Lambrechtse P; Ziesenitz VC; Atkinson A; Bos EJ; Welzel T; Gilgen Y; Gürtler N; Heuscher S; Cohen AF; van den Anker JN. European journal of pediatrics. 2021.

Neonatal and Pediatric Dose Selection: Quo Vadis?

Burckart GJ; van den Anker JN. Journal of Clinical Pharmacology. 2021.

Not Only Preterm Neonates Mature but Also Traditional Dosing Regimens Have to Mature: The Role of Mathematical Modeling.

Koch G; van den Anker JN. . 2021.

Optimal use of intravenous tranexamic acid for hemorrhage prevention in pregnant women.

Ahmadzia HK; Luban NLC; Li S; Guo D; Miszta A; Gobburu JVS; Berger JS; James AH; Wolberg AS; van den Anker J. American journal of obstetrics and gynecology. 2021.

Pharmacokinetics and safety of pegylated recombinant human granulocyte colony-stimulating factor in children with acute leukaemia.

Liu XT; Zhao YX; Jia GW; Yang F; Zhang CZ; Han B; Dai JH; Han YQ; Tang BH; Yang XM; Shi HY; Zhou Y; Sui ZG; Chen JZ; van den Anker JN; Zhao W. British Journal of Clinical Pharmacology. 2021.

Pharmacological treatment of neonatal pain: are we ready for a paradigm shift? Comment on Br J Anaesth 2021; 126: e133-5.

van den Anker JN. . 2021.

Pharmacometric Evaluation of Umbilical Cord Blood Concentration-Based Early Initiation of Treatment in Methadone-Exposed Preterm Neonates.

Samiee-Zafarghandy S; van Donge T; Allegaert K; van den Anker J. Children. 2021.

Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir.

Liu XI; Momper JD; Rakhmanina NY; Green DJ; Burckart GJ; Cressey TR; Mirochnick M; Best BM; van den Anker JN; Dallmann A. Clinical Pharmacokinetics. 2021.

Population Model of Serum Creatinine as Time-Dependent Covariate in Neonates.

Krzyzanski W; Smits A; Van Den Anker J; Allegaert K. The AAPS journal. 2021.

Population Pharmacokinetics and Dosing Optimization of Amoxicillin in Chinese Infants

Wu Y.-E.; Wang Y.-K.; Tang B.-H.; Dong L.; Li X.; Zhang W.; Li D.-F.; Tian L.-Y.; van den Anker J.; You D.-P.; Zhao W.. Journal of Clinical Pharmacology. 2021.

Population pharmacokinetics and dosing optimization of azlocillin in neonates with early-onset sepsis: a real-world study.

Wu YE; Wang T; Yang HL; Tang BH; Kong L; Li X; Gao Q; Li X; Yao BF; Shi HY; Huang X; Wang WQ; Jacqz-Aigrain E; Allegaert K; van den Anker J; Tian XY; Zhao W. Journal of Antimicrobial Chemotherapy. 2021.

Population Pharmacokinetics and Dosing Optimization of Vancomycin in Infants, Children, and Adolescents with Augmented Renal Clearance.

He CY; Ye PP; Liu B; Song L; van den Anker J; Zhao W. Antimicrobial Agents and Chemotherapy. 2021.

Population pharmacokinetics and pharmacodynamics of Tranexamic acid in women undergoing caesarean delivery.

Li S; Ahmadzia HK; Guo D; Dahmane E; Miszta A; Luban NLC; Berger JS; James AH; Wolberg AS; van den Anker JN; Gobburu JVS. British Journal of Clinical Pharmacology. 2021.

Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance.

Du B; Zhou Y; Tang BH; Wu YE; Yang XM; Shi HY; Yao BF; Hao GX; You DP; van den Anker J; Zheng Y; Zhao W. Frontiers in Pharmacology. 2021.

Prescription Drug Shortages: Pediatric Emergency and Critical Care Medications.

Donnelly KA; Zocchi MS; Katy TA; Fox ER; Pines JM; van den Anker JN; Mazer-Amirshahi ME. Pediatric emergency care. 2021.

Preventing Home Medication Administration Errors.

Yin HS; Neuspiel DR; Paul IM; Franklin W; Tieder JS; Adirim T; Alvarez F; Brown JM; Bundy DG; Ferguson LE; Gleeson SP; Leu M; Mueller BU; Connor Phillips S; Quinonez RA; Rea C; Rinke ML; Shaikh U; Shiffman RN; Vickers Saarel E; Spencer Cockerham SP; Mack Walsh K; Jones B; Adler AC; Foster JH; Green TP; Houck CS; Laughon MM; Neville K; Reigart JR; Shenoi R; Sullivan JE; Van Den Anker JN; Verhoef PA. Pediatrics. 2021.

Serum Creatinine and Serum Cystatin C are Both Relevant Renal Markers to Estimate Vancomycin Clearance in Critically Ill Neonates.

Leroux S; Biran V; van den Anker J; Gotta V; Zhao W; Zhang D; Jacqz-Aigrain E; Pfister M. Frontiers in Pharmacology. 2021.

Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland.

Kohns Vasconcelos M; Meyer Sauteur PM; Keitel K; Santoro R; Heininger U; van den Anker J; Bielicki JA. The Pediatric infectious disease journal. 2021.

Topical nitroglycerin ointment as salvage therapy for peripheral tissue ischemia in newborns: a systematic review.

Sushko K; Litalien C; Ferruccio L; Gilpin A; Mazer-Amirshahi M; Chan AK; van den Anker J; Lacaze-Masmonteil T; Samiee-Zafarghandy S. CMAJ open. 2021.

Acetaminophen use in pregnant women and their neonates: Safe or unsafe till proven otherwise?

Van Den Anker J.N.; Allegaert K.. Neonatology. 2020.

Age appropriate reference intervals for eight kidney function and injury markers in infants, children and adolescents.

van Donge T; Staub E; Atkinson A; Gotta V; van den Anker J; Risch L; Welzel T; Pfister M. Clinical Chemistry and Laboratory Medicine. 2020.

Amoxicillin Dosing Regimens for the Treatment of Neonatal Sepsis: Balancing Efficacy and Neurotoxicity.

van Donge T; Fuchs A; Leroux S; Pfister M; Rodieux F; Atkinson A; Giannoni E; van den Anker J; Bielicki J. Neonatology. 2020.

Anatomical and physiological alterations of pregnancy.

Kazma JM; van den Anker J; Allegaert K; Dallmann A; Ahmadzia HK. Journal of Pharmacokinetics and Pharmacodynamics. 2020.

Approaches to dose finding in neonates, illustrating the variability between neonatal drug development programs

Van den Anker J.N.; McCune S.; Annaert P.; Baer G.R.; Mulugeta Y.; Abdelrahman R.; Wu K.; Krudys K.M.; Fisher J.; Slikker W.; Chen C.; Burckart G.J.; Allegaert K.. Pharmaceutics. 2020.

Beyond the Randomized Clinical Trial: Innovative Data Science to Close the Pediatric Evidence Gap.

Goulooze SC; Zwep LB; Vogt JE; Krekels EHJ; Hankemeier T; van den Anker JN; Knibbe CAJ. Clinical Pharmacology and Therapeutics. 2020.

Carbapenem-Resistant Enterobacteriaceae Bloodstream Infection Treated Successfully With High-Dose Meropenem in a Preterm Neonate

Wu Y.-E.; Xu H.-Y.; Shi H.-Y.; van den Anker J.; Chen X.-Y.; Zhao W.. Frontiers in Pharmacology. 2020.

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties.

Smit C; Peeters MYM; van den Anker JN; Knibbe CAJ. Clinical Pharmacokinetics. 2020.

Clinical Pharmacology and Pharmacometrics to Better Understand Physiological Changes During Pregnancy and Neonatal Life.

van Donge T; Evers K; Koch G; van den Anker J; Pfister M. Handbook of Experimental Pharmacology. 2020.

Combined Pediatric and Adult Trials Submitted to the US Food and Drug Administration 2012–2018

Tanaudommongkon I.; John Miyagi S.; Green D.J.; Burnham J.M.; van den Anker J.N.; Park K.; Wu J.; McCune S.K.; Yao L.; Burckart G.J.. Clinical Pharmacology and Therapeutics. 2020.

Creatinine Trends to Detect Ibuprofen-Related Maturational Adverse Drug Events in Neonatal Life: A Simulation Study for the ELBW Newborn.

van Donge T; Allegaert K; Pfister M; Smits A; van den Anker J. Frontiers in Pharmacology. 2020.

Exposure-Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy

Li X.; Conklin L.S.; van den Anker J.; Hoffman E.P.; Clemens P.R.; Jusko W.J.. Journal of Clinical Pharmacology. 2020.

Implications of Perioperative Polypharmacy in Adolescents Undergoing Bariatric Surgery: a Single-Center Experience

Williams E.F.; Vaughns J.D.; Mackey E.R.; Muret J.C.; Nadler E.P.; van den Anker J.N.. Obesity Surgery. 2020.

Integration of Placental Transfer in a Fetal-Maternal Physiologically Based Pharmacokinetic Model to Characterize Acetaminophen Exposure and Metabolic Clearance in the Fetus.

Mian P; Allegaert K; Conings S; Annaert P; Tibboel D; Pfister M; van Calsteren K; van den Anker JN; Dallmann A. Clinical Pharmacokinetics. 2020.

Long-term safety of prenatal and neonatal exposure to paracetamol: a protocol for a systematic review.

Samiee-Zafarghandy S; Sushko K; Van Den Anker J. . 2020.

Narcotic-Sparing Approaches and the Shift Toward Paracetamol in Neonatal Intensive Care.

Allegaert K; Tibboel D; van den Anker J. Handbook of Experimental Pharmacology. 2020.

New Ways to Measure the Effect of Pharmacotherapy in Newborn Infants: Feasible or Not That Much?

Van Den Anker J.N.. Neonatology. 2020.

Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology.

Schrier L; Hadjipanayis A; Stiris T; Ross-Russell RI; Valiulis A; Turner MA; Zhao W; De Cock P; de Wildt SN; Allegaert K; van den Anker J. European journal of pediatrics. 2020.

Optimal dosing of ceftriaxone in infants based on a developmental population pharmacokinetic-pharmacodynamic analysis

Wang Y.-K.; Wu Y.E.; Li X.; Tian L.-Y.; Khan M.W.; Tang B.-H.; Shi H.-Y.; Zheng Y.; Hao G.-X.; van den Anker J.; You D.-P.; Zhao W.. Antimicrobial Agents and Chemotherapy. 2020.

Oral drugs used to treat persistent pulmonary hypertension of the newborn.

Zhang W; Wu YE; Yang XY; Shi J; van den Anker J; Song LL; Zhao W. Expert Review of Clinical Pharmacology. 2020.

Pediatric drug data in Canadian drug monographs: a descriptive analysis.

Raja P; Duffett M; Mazer-Amirshahi M; Patel A; Gilpin A; Litalien C; Chan AK; van den Anker J; Lacaze-Masmonteil T; Samiee-Zafarghandy S. CMAJ open. 2020.

Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women.

Mian P; van den Anker JN; van Calsteren K; Annaert P; Tibboel D; Pfister M; Allegaert K; Dallmann A. Clinical Pharmacokinetics. 2020.

Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling

Liu X.I.; Momper J.D.; Rakhmanina N.Y.; Green D.J.; Burckart G.J.; Cressey T.R.; Mirochnick M.; Best B.M.; van den Anker J.N.; Dallmann A.. Clinical Pharmacokinetics. 2020.

Preface

Kiess W.; Schwab M.; van den Anker J.. . 2020.

Preterm health: time to bridge the evidence gap

Slater R.; Moultrie F.; Bax R.; van den Anker J.; Bhatt A.. The Lancet. 2020.

Prophylactic Use of Enoxaparin in Adolescents During Bariatric Surgery-a Prospective Clinical Study.

Vaughns JD; Ziesenitz VC; Williams EF; Nadler EP; Mikus G; van den Anker J. Obesity Surgery. 2020.

Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the KIDS-STEP trial.

Kohns Vasconcelos M; Meyer Sauteur PM; Santoro R; Coslovsky M; Lurà M; Keitel K; Wachinger T; Beglinger S; Heininger U; van den Anker J; Bielicki JA. BMJ Open. 2020.

Renal Precision Medicine in Neonates and Acute Kidney Injury: How to Convert a Cloud of Creatinine Observations to Support Clinical Decisions

Allegaert K.; Smits A.; van Donge T.; van den Anker J.; Sarafidis K.; Levtchenko E.; Mekahli D.. Frontiers in Pediatrics. 2020.

Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease.

Batra SK; Heier CR; Diaz-Calderon L; Tully CB; Fiorillo AA; van den Anker J; Conklin LS. Inflammatory Bowel Diseases. 2020.

Special management considerations for propranolol use in breastfed infants of mothers taking antihypertensives

Aizman L.; Van Den Anker J.; Tender J.; Krishnan A.; Kirkorian A.Y.. Pediatric dermatology. 2020.

Treatment of Rare Inflammatory Kidney Diseases: Drugs Targeting the Terminal Complement Pathway.

Anliker-Ort M; Dingemanse J; van den Anker J; Kaufmann P. Frontiers in Immunology. 2020.

A Comparison of Pediatric and Adult Safety Studies for Antipsychotic and Antidepressant Drugs Submitted to the United States Food and Drug Administration.

Liu XI; Schuette P; Burckart GJ; Green DJ; La J; Burnham JM; Rakhmanina N; Robb A; Huang SM; van den Anker JN. Journal of Pediatrics. 2019.

Age-Dependent Changes of Kidney Injury Biomarkers in Pediatrics.

van Donge T; Welzel T; Atkinson A; van den Anker J; Pfister M. Journal of Clinical Pharmacology. 2019.

Analgesic Requirements in Adolescents Undergoing Bariatric Surgery-an Observational Study

Vaughns, Janelle D; Williams, Elaine F; Mackey, Eleanor R; Muret, Jane C; van den Anker, John; Nadler, Evan P; Quezado, Zenaide M. Obesity Surgery. 2019.

A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MATERNAL-FETAL MODEL OF RALTEGRAVIR AND DOLUTEGRAVIR.

Liu, X.; Momper, J.; Rakhmanina, N.; Cressey, T.; Mirochnick, M.; Best, B. M.; van den Anker, J.; Dallmann, A.. Clinical Pharmacology and Therapeutics. 2019.

Author response.

Welzel T; Ziesenitz VC; Seitz S; Donner B; van den Anker JN. . 2019.

Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis.

Hahn A; Fanous H; Jensen C; Chaney H; Sami I; Perez GF; Koumbourlis AC; Louie S; Bost JE; van den Anker JN; Freishtat RJ; Zemanick ET; Crandall KA. Scientific Reports. 2019.

Characterization of Maternal and Neonatal Pharmacokinetic Behavior of Ceftazidime.

Dallmann A; van den Anker J; Pfister M; Koch G. Journal of Clinical Pharmacology. 2019.

Clinical Pharmacokinetic Studies in Pregnant Women and the Relevance of Pharmacometric Tools.

Dallmann A; Mian P; Van den Anker J; Allegaert K. Current Pharmaceutical Design. 2019.

Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Common Problem Drugs and How to Prescribe Them.

Donnenberg VS; Chaikin P; Mandic M; Meibohm B; van den Anker J; Rhinehart E; Nafziger AN; Burris JF; American College of Clinical Pharmacology. Journal of Clinical Pharmacology. 2019.

Creating a Pharmacotherapy Collaborative Practice Network to Manage Medications for Children and Youth: A Population Health Perspective.

Parrish II RH; Casher D; van den Anker J; Benavides S. Children. 2019.

Creating a Pharmacotherapy Collaborative Practice Network to Manage Medications for Children and Youth: A Population Health Perspective.

Parrish II RH; Casher D; van den Anker J; Benavides S. Children. 2019.

Creating a Pharmacotherapy Collaborative Practice Network to Manage Medications for Children and Youth: A Population Health Perspective.

Parrish II RH; Casher D; van den Anker J; Benavides S. Children. 2019.

Creating a Pharmacotherapy Collaborative Practice Network to Manage Medications for Children and Youth: A Population Health Perspective.

Parrish II RH; Casher D; van den Anker J; Benavides S. Children. 2019.

Developmental Pharmacodynamics and Modeling in Pediatric Drug Development.

Conklin LS; Hoffman EP; van den Anker J. Journal of Clinical Pharmacology. 2019.

Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy.

Hathout Y; Liang C; Ogundele M; Xu G; Tawalbeh SM; Dang UJ; Hoffman EP; Gordish-Dressman H; Conklin LS; van den Anker JN; Clemens PR; Mah JK; Henricson E; McDonald C. Scientific Reports. 2019.

Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study.

Ziesenitz VC; Rodieux F; Atkinson A; Borter C; Bielicki JA; Haschke M; Duthaler U; Bachmann F; Erb TO; Gürtler N; Holland-Cunz S; van den Anker JN; Gotta V; Pfister M. European Journal of Clinical Pharmacology. 2019.

Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal-Fetal Drug Transfer.

Dallmann A; Liu XI; Burckart GJ; van den Anker J. Journal of Clinical Pharmacology. 2019.

Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years - a randomized, double-blind, placebo-controlled trial.

Beuter C; Volkers G; Radic T; Goldberg J; van den Anker J. Journal of pain research. 2019.

Interventional cohort study of prolonged use (>72 hours) of paracetamol in neonates: protocol of the PARASHUTE study.

Haslund-Krog SS; Hertel S; Dalhoff K; Poulsen S; Christensen U; Wilkins D; van den Anker J; Brink Henriksen T; Holst H. BMJ paediatrics open. 2019.

Intravenous or Oral Acetaminophen for Analgesia After Cesarean Section: Exposure Drives Pain Relief.

Mian P; Dallmann A; van den Anker JN; Tibboel D; Allegaert K. Pain medicine (Malden, Mass.). 2019.

Making Meaningful Improvements in Pharmacotherapy and Medication Management for Children and Youth-A Modest Proposal.

Parrish II RH; van den Anker J; Benavides S. . 2019.

Management of anaphylaxis and allergies in patients with long QT syndrome Response

Welzel, Tatjana; Ziesenitz, Victoria C.; Seitz, Stefanie; Donner, Birgit; van den Anker, Johannes N.. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2019.

Maternal paracetamol intake and fetal ductus arteriosus constriction or closure: a case series analysis.

Allegaert K; Mian P; Lapillonne A; van den Anker JN. British Journal of Clinical Pharmacology. 2019.

Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates.

Leroux S; van den Anker JN; Smits A; Pfister M; Allegaert K. British Journal of Clinical Pharmacology. 2019.

Methadone dosing strategies in preterm neonates can be simplified.

van Donge T; Samiee-Zafarghandy S; Pfister M; Koch G; Kalani M; Bordbar A; van den Anker J. British Journal of Clinical Pharmacology. 2019.

Monoclonal Antibodies and Fc-Fusion Proteins for Pediatric Use: Dosing, Immunogenicity, and Modeling and Simulation in Data Submitted to the US Food and Drug Administration.

Liu XI; Dallmann A; Wang YM; Green DJ; Burnham JM; Chiang B; Wu P; Sheng M; Lu K; van den Anker JN; Burckart GJ. Journal of Clinical Pharmacology. 2019.

Morphine treatment for neonatal abstinence syndrome: huge dosing variability underscores the need for a better clinical study design.

Mian P; Tibboel D; Wildschut ED; van den Anker JN; Allegaert K. MINERVA PEDIATRICA. 2019.

Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice.

Vila MC; Novak JS; Benny Klimek M; Li N; Morales M; Fritz AG; Edwards K; Boehler JF; Hogarth MW; Kinder TB; Zhang A; Mazala D; Fiorillo AA; Douglas B; Chen YW; van den Anker J; Lu QL; Hathout Y; Hoffman EP; Partridge TA; Nagaraju K. Journal of Pathology. 2019.

Neonates are not just little children and need more finesse in dosing of antibiotics.

Allegaert K; van den Anker J. Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine. 2019.

Next Generation Medical Management of Postpartum Hemorrhage.

Phillips JM; van den Anker JN; Ahmadzia HK. Current Pharmaceutical Design. 2019.

Ontogeny of Phase I Metabolism of Drugs.

Allegaert K; van den Anker J. Journal of Clinical Pharmacology. 2019.

Paediatric extrapolation: the panacea for paediatric drug development?

van den Anker J. British Journal of Clinical Pharmacology. 2019.

Pediatric Ontogeny: Moving From Translational Science to Drug Development.

Burckart GJ; van den Anker JN. Journal of Clinical Pharmacology. 2019.

Pediatric Renal Ontogeny and Applications in Drug Development.

Zhang Y; Mehta N; Muhari-Stark E; Burckart GJ; van den Anker J; Wang J. Journal of Clinical Pharmacology. 2019.

Perinatal Clinical Pharmacology: Optimizing Pharmacotherapy for Pregnant Women, Their Fetuses and Infants.

Allegaert K; van den Anker JN. Current Pharmaceutical Design. 2019.

Personalized weight change prediction in the first week of life.

Wilbaux M; Kasser S; Gromann J; Mancino I; Coscia T; Lapaire O; van den Anker JN; Pfister M; Wellmann S. Clinical nutrition (Edinburgh, Scotland). 2019.

Phenobarbital Increases Midazolam Clearance in Neonates Treated with Hypothermia: Do We Really Need to Know?

Allegaert K; Smits A; van den Anker JN. Neonatology. 2019.

PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING TO CHARACTERIZE ACETAMINOPHEN TARGET ATTAINMENT AND HEPATOTOXICITY IN NON-PREGNANT AND PREGNANT WOMEN.

Mian, P.; van den Anker, J.; van Calsteren, K.; Annaert, P.; Tibboel, D.; Pfister, M.; Allegaert, K.; Dallmann, A.. Clinical Pharmacology and Therapeutics. 2019.

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir.

Liu, Xiaomei I; Momper, Jeremiah D; Rakhmanina, Natella; van den Anker, John N; Green, Dionna J; Burckart, Gilbert J; Best, Brookie M; Mirochnick, Mark; Capparelli, Edmund V; Dallmann, André. Journal of Clinical Pharmacology. 2019.

Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants

Jacqz-Aigrain, Evelyne; Leroux, Stéphanie; Thomson, Alison H; Allegaert, Karel; Capparelli, Edmund V; Biran, Valérie; Simon, Nicolas; Meibohm, Bernd; Lo, Yoke-Lin; Marques, Remedios; Peris, José-Esteban; Lutsar, Irja; Saito, Jumpei; Nakamura, Hidefumi; van den Anker, Johannes N; Sharland, Mike; Zhao, Wei. Journal of Antimicrobial Chemotherapy. 2019.

Population Pharmacokinetic Modeling in the Presence of Missing Time-Dependent Covariates: Impact of Body Weight on Pharmacokinetics of Paracetamol in Neonates.

Krzyzanski W; Cook SF; Wilbaux M; Sherwin CMT; Allegaert K; Vermeulen A; van den Anker JN. AAPS Journal. 2019.

Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population

Watson, Estelle; Khandelwal, Akash; Freijer, Jan; van den Anker, John; Lefeber, Claudia; Eerdekens, Marielle. Journal of pain research. 2019.

Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy.

Mavroudis PD; van den Anker J; Conklin LS; Damsker JM; Hoffman EP; Nagaraju K; Clemens PR; Jusko WJ. Journal of Clinical Pharmacology. 2019.

PREDICTION FETAL EXPOSURE TO ACETAMINOPHEN AND ITS METABOLITES USING PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING.

Mian, P.; Dallmann, A.; Conings, S.; Annaert, P.; Tibboel, D.; Pfister, M.; van Calsteren, K.; van den Anker, J.; Allegaert, K.. Clinical Pharmacology and Therapeutics. 2019.

Prescription Drug Shortages: Impact on Neonatal Intensive Care.

Ziesenitz VC; Fox E; Zocchi M; Samiee-Zafarghandy S; van den Anker JN; Mazer-Amirshahi M. Neonatology. 2019.

Prevalence of high-risk drug-drug interactions in paediatric inpatients: a retrospective, single-centre cohort analysis.

Dieu LW; Leuppi-Taegtmeyer AB; van den Anker J; Trachsel D; Gotta V. Swiss medical weekly. 2019.

Psychiatric Disorder or Adverse Drug Reaction? - How CYP2D6 Metabolizing Activity Can Result in Dextromethorphan Intoxication.

Ziesenitz VC; van den Anker JN. Klinische Padiatrie. 2019.

Rational Use of Antibiotics in Neonates: Still in Search of Tailored Tools.

van den Anker J; Allegaert K. Healthcare (Basel, Switzerland). 2019.

Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model.

Völler S; Flint RB; Beggah F; Reiss I; Andriessen P; Zimmermann LJI; van den Anker JN; Liem KD; Koch BCP; de Wildt S; Knibbe CAJ; Simons SHP. Journal of Clinical Pharmacology. 2019.

Research on medication use in the neonatal intensive care unit.

Allegaert K; Simons S; Van Den Anker J. Expert Review of Clinical Pharmacology. 2019.

Severity of asphyxia is a covariate of phenobarbital clearance in newborns undergoing hypothermia.

Pokorná P; Posch L; Šíma M; Klement P; Slanar O; van den Anker J; Tibboel D; Allegaert K. Journal of Maternal-Fetal and Neonatal Medicine. 2019.

Surrogate Endpoints in Pediatric Studies Submitted to the US FDA.

Green DJ; Sun H; Burnham J; Liu XI; van den Anker J; Temeck J; Yao L; McCune SK; Burckart GJ. Clinical Pharmacology and Therapeutics. 2019.

The challenge of developing pain medications for children: therapeutic needs and future perspectives.

Eerdekens M; Beuter C; Lefeber C; van den Anker J. Journal of pain research. 2019.

Toolkit for Population Health Initiatives Around the Globe Related to Collaborative Comprehensive Medication Management for Children and Youth.

Parrish Ii RH; van den Anker J. Children. 2019.

Use of a personalized phenytoin dosing approach to manage difficult to control seizures in an infant with a SCN2A mutation.

Welzel T; Ziesenitz VC; Waldvogel S; Scheidegger S; Weber P; van den Anker JN; Gotta V. European Journal of Clinical Pharmacology. 2019.

Use of inhaled steroids to prevent bronchopulmonary dysplasia: a matter of great debate.

Samiee-Zafarghandy S; van den Anker JN. Archives of Disease in Childhood. 2019.

Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function.

Hoffman EP; Schwartz BD; Mengle-Gaw LJ; Smith EC; Castro D; Mah JK; McDonald CM; Kuntz NL; Finkel RS; Guglieri M; Bushby K; Tulinius M; Nevo Y; Ryan MM; Webster R; Smith AL; Morgenroth LP; Arrieta A; Shimony M; Siener C; Jaros M; Shale P; McCall JM; Nagaraju K; van den Anker J; Conklin LS; Cnaan A; Gordish-Dressman H; Damsker JM; Clemens PR; Cooperative International Neuromuscular Research Group. . 2019.

Where are the Ambulatory Care Pediatric Pharmacists?

Parrish RH 2nd; van den Anker J; Benavides S. Children. 2019.

Acetaminophen in the Neonatal Intensive Care Unit: Shotgun Approach or Silver Bullet.

van den Anker JN; Allegaert K. Journal of Pediatrics. 2018.

Analgesics and Sedatives in Critically Ill Newborns and Infants: The Impact on Long-Term Neurodevelopment.

Schiller RM; Allegaert K; Hunfeld M; van den Bosch GE; van den Anker J; Tibboel D. Journal of Clinical Pharmacology. 2018.

Antibiotic therapy in neonates and impact on gut microbiota and antibiotic resistance development: a systematic review.

Fjalstad JW; Esaiassen E; Juvet LK; van den Anker JN; Klingenberg C. Journal of Antimicrobial Chemotherapy. 2018.

Antibiotic use for community-acquired pneumonia in neonates and children: WHO evidence review.

Mathur S; Fuchs A; Bielicki J; Van Den Anker J; Sharland M. Paediatrics and International Child Health. 2018.

Author's Reply to Reith: "Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults".

van Rongen A; van den Anker JN; Knibbe CAJ. Clinical Pharmacokinetics. 2018.

Comorbidity of Migraine and Epilepsy in Pediatrics: A Review.

Jancic J; Djuric V; Hencic B; van den Anker JN; Samardzic J. JOURNAL OF CHILD NEUROLOGY. 2018.

Correction to: Pharmacokinetics of Fentanyl and Its Derivatives in Children: A Comprehensive Review.

Ziesenitz VC; Vaughns JD; Koch G; Mikus G; van den Anker JN. Clinical Pharmacokinetics. 2018.

Developmental Changes in Pharmacokinetics and Pharmacodynamics.

van den Anker J; Reed MD; Allegaert K; Kearns GL. Journal of Clinical Pharmacology. 2018.

Developmental Pharmacotherapy: The Interface Between Ontogeny and Drug Effect.

Reed MD; van den Anker J. Journal of Clinical Pharmacology. 2018.

Drug evaluation studies in neonates: how to overcome the current limitations.

Allegaert K; Smits A; van den Anker JN. Expert Review of Clinical Pharmacology. 2018.

Drug metabolism in early infancy: opioids as an illustration.

Van Donge T; Mian P; Tibboel D; Van Den Anker J; Allegaert K. Expert opinion on drug metabolism & toxicology. 2018.

Evident bias in a paracetamol metabolite population pharmacokinetic model applied to an external dataset.

Roberts JK; Linakis MW; Liu X; Sherwin CMT; van den Anker JN. British Journal of Clinical Pharmacology. 2018.

First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates.

Brussee JM; Yu H; Krekels EHJ; de Roos B; Brill MJE; van den Anker JN; Rostami-Hodjegan A; de Wildt SN; Knibbe CAJ. CPT: pharmacometrics &amp; systems pharmacology. 2018.

Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults.

van Rongen A; Brill MJE; Vaughns JD; Välitalo PAJ; van Dongen EPA; van Ramshorst B; Barrett JS; van den Anker JN; Knibbe CAJ. Clinical Pharmacokinetics. 2018.

How reliable are commercially available trackers in detecting daytime sleep.

Lambrechtse P; Ziesenitz VC; Cohen A; van den Anker JN; Bos EJ. British Journal of Clinical Pharmacology. 2018.

Key Components for Antibiotic Dose Optimization of Sepsis in Neonates and Infants.

van Donge T; Bielicki JA; van den Anker J; Pfister M. Frontiers in Pediatrics. 2018.

Longitudinal trends in U.S. shortages of sterile solutions, 2001-17.

Mazer-Amirshahi M; Fox ER; Zocchi MS; Pines JM; van den Anker JN. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY. 2018.

Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia.

Bassler D; Shinwell ES; Hallman M; Jarreau PH; Plavka R; Carnielli V; Meisner C; Engel C; Koch A; Kreutzer K; van den Anker JN; Schwab M; Halliday HL; Poets CF; Neonatal European Study of Inhaled Steroids Trial Group. New England Journal of Medicine. 2018.

Management of anaphylaxis and allergies in patients with long QT syndrome: A review of the current evidence.

Welzel T; Ziesenitz VC; Seitz S; Donner B; van den Anker JN. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2018.

Neonatal Pharmacology

Allegaert K.; Ward R.M.; Van Den Anker J.N.. . 2018.

No, we are not-we keep forgetting the right ventricle.

Ziesenitz VC; Haefeli WE; van den Anker JN; Gorenflo M. European Journal of Clinical Pharmacology. 2018.

Obesity and Pediatric Drug Development.

Vaughns JD; Conklin LS; Long Y; Zheng P; Faruque F; Green DJ; van den Anker JN; Burckart GJ. Journal of Clinical Pharmacology. 2018.

Perspectives in Neonatal Pharmacology: Drug Discovery, Knowledge Integration and Structured Prioritization.

Allegaert K; Smits A; Simons S; Van den Anker J. Current Pharmaceutical Design. 2018.

Pharmacokinetics of Fentanyl and Its Derivatives in Children: A Comprehensive Review.

Ziesenitz VC; Vaughns JD; Koch G; Mikus G; van den Anker JN. Clinical Pharmacokinetics. 2018.

Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.

Conklin LS; Damsker JM; Hoffman EP; Jusko WJ; Mavroudis PD; Schwartz BD; Mengle-Gaw LJ; Smith EC; Mah JK; Guglieri M; Nevo Y; Kuntz N; McDonald CM; Tulinius M; Ryan MM; Webster R; Castro D; Finkel RS; Smith AL; Morgenroth LP; Arrieta A; Shimony M; Jaros M; Shale P; McCall JM; Hathout Y; Nagaraju K; van den Anker J; Ward LM; Ahmet A; Cornish MR; Clemens PR. Pharmacological research. 2018.

Physiologically Based Pharmacokinetic Modeling in Pregnancy: A Systematic Review of Published Models.

Dallmann A; Pfister M; van den Anker J; Eissing T. Clinical Pharmacology and Therapeutics. 2018.

Polymorphic Expression of UGT1A9 is Associated with Variable Acetaminophen Glucuronidation in Neonates: A Population Pharmacokinetic and Pharmacogenetic Study.

Linakis MW; Cook SF; Kumar SS; Liu X; Wilkins DG; Gaedigk R; Gaedigk A; Sherwin CMT; van den Anker JN. Clinical Pharmacokinetics. 2018.

Population Pharmacokinetics of Intramuscular and Intravenous Ketamine in Children.

Hornik CP; Gonzalez D; van den Anker J; Atz AM; Yogev R; Poindexter BB; Ng KC; Delmore P; Harper BL; Melloni C; Lewandowski A; Gelber C; Cohen-Wolkowiez M; Lee JH; Pediatric Trial Network Steering Committee. Journal of Clinical Pharmacology. 2018.

Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.

Brussee JM; Vet NJ; Krekels EHJ; Valkenburg AJ; Jacqz-Aigrain E; van Gerven JMA; Swart EL; van den Anker JN; Tibboel D; de Hoog M; de Wildt SN; Knibbe CAJ. British Journal of Clinical Pharmacology. 2018.

Prescription Drug Shortages: Implications for Ambulatory Pediatrics.

Donnelly KA; Zocchi MS; Katy TA; Fox ER; van den Anker JN; Mazer-Amirshahi ME. Journal of Pediatrics. 2018.

Primary Endpoints in Pediatric Efficacy Trials Submitted to the US FDA.

Green DJ; Burnham JM; Schuette P; Liu XI; Maas BM; Yao L; McCune SK; Chen J; van den Anker JN; Burckart GJ. Journal of Clinical Pharmacology. 2018.

Quantitative Analysis of Gentamicin Exposure in Neonates and Infants Calls into Question Its Current Dosing Recommendations.

van Donge T; Pfister M; Bielicki J; Csajka C; Rodieux F; van den Anker J; Fuchs A. Antimicrobial Agents and Chemotherapy. 2018.

Reviewing the WHO guidelines for antibiotic use for sepsis in neonates and children.

Fuchs A; Bielicki J; Mathur S; Sharland M; Van Den Anker JN. Paediatrics and International Child Health. 2018.

Safety of dipyrone (metamizole) in children-What's the risk of agranulocytosis?

Ziesenitz VC; Erb TO; Trachsel D; van den Anker JN. Paediatric anaesthesia. 2018.

Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis

Conklin, Laurie S.; Merkel, Peter A.; Pachman, Lauren M.; Parikh, Hemang; Tawalbeh, Shefa; Damsker, Jesse M.; Cuthbertson, David D.; Morgan, Gabrielle A.; Monach, Paul A.; Hathout, Yetrib; Nagaraju, Kanneboyina; van den Anker, John; McAlear, Carol A.; Hoffman, Eric P.. STEROIDS. 2018.

Antibiotic exposure in neonates and early adverse outcomes: a systematic review and meta-analysis

Esaiassen, Eirin; Fjalstad, Jon Widding; Juvet, Lene Kristine; van den Anker, John N.; Klingenberg, Claus. Journal of Antimicrobial Chemotherapy. 2017.

Augmented Renal Clearance in Critically Ill Pediatric Patients: Does It Impact the Outcome of Pharmacotherapy?

van den Anker, John N.; Knibbe, Catherijne A. J.; Tibboel, Dick. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2017.

Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates.

Koch G; Datta AN; Jost K; Schulzke SM; van den Anker J; Pfister M. Journal of Pediatrics. 2017.

CAFFEINE CITRATE DOSING ADJUSTMENT TO MAINTAIN TARGET CAFFEINE CONCENTRATION IN PRETERM NEONATES

Koch, G.; van den Anker, J.; Jost, K.; Datta, A.; Pfister, M.. Clinical Pharmacology and Therapeutics. 2017.

Clinical pharmacology of analgosedatives in neonates: ways to improve their safe and effective use

Smits, Anne; Allegaert, Karel; van den Anker, John N.. JOURNAL OF PHARMACY AND PHARMACOLOGY. 2017.

Clinical trials of medicines in children

K Allegaert; J van den Anker. . 2017.

Developmental Pharmacokinetics in Neonates: Maturational Changes and Beyond.

Allegaert K; Mian P; van den Anker JN. Current Pharmaceutical Design. 2017.

Drawbacks of analgesics in neonatal age: how to ensure safe and effective use in newborns

K Allegaert; J van den Anker. . 2017.

Editorial: Neonatal Clinical Pharmacology: A Rapidly Maturing Discipline.

Allegaert K; van den Anker JN. Current Pharmaceutical Design. 2017.

Efficacy and Safety of Ibuprofen in Infants Aged Between 3 and 6 Months.

Ziesenitz VC; Zutter A; Erb TO; van den Anker JN. Paediatric drugs. 2017.

Erratum to: Use of Fentanyl in Adolescents with Clinically Severe Obesity Undergoing Bariatric Surgery: A Pilot Study.

Vaughns JD; Ziesenitz VC; Williams EF; Mushtaq A; Bachmann R; Skopp G; Weiss J; Mikus G; van den Anker JN. Paediatric drugs. 2017.

Evidence-based drug treatment for special patient populations through model-based approaches.

Krekels EHJ; van Hasselt JGC; van den Anker JN; Allegaert K; Tibboel D; Knibbe CAJ. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2017.

Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants.

Flint RB; Roofthooft DW; van Rongen A; van Lingen RA; van den Anker JN; van Dijk M; Allegaert K; Tibboel D; Knibbe CAJ; Simons SHP. Pediatric Research. 2017.

Harmonized Use of Frequently Prescribed Medicines in Preterm Neonates: Mission Impossible?

van den Anker, John N.; Allegaert, Karel. Journal of Pediatrics. 2017.

How to optimise drug study design: pharmacokinetics and pharmacodynamics studies introduced to paediatricians

Vermeulen, Eric; van den Anker, John N.; Della Pasqua, Oscar; Hoppu, Kalle; van der Lee, Johanna H.. JOURNAL OF PHARMACY AND PHARMACOLOGY. 2017.

Inhaled Drugs and Systemic Corticosteroids for Bronchopulmonary Dysplasia

Bassler, Dirk; van den Anker, John. PEDIATRIC CLINICS OF NORTH AMERICA. 2017.

Non-maturational covariates for dynamic systems pharmacology models in neonates, infants, and children: Filling the gaps beyond developmental pharmacology

Allegaert, Karel; Tibboel, Dick; Simons, Sinno H. P.; Krekels, Elke H.; Knibbe, Catherijne A.; van den Anker, John N.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2017.

Optimising β -lactam Dosing in Neonates: A Review of Pharmacokinetics, Drug Exposure and Pathogens.

Fuchs A; Li G; van den Anker JN; Bielicki J. Current Pharmaceutical Design. 2017.

Paracetamol and morphine for infant and neonatal pain; still a long way to go?

Baarslag, Manuel A.; Allegaert, Karel; Van Den Anker, John N.; Knibbe, Catherijne A. J.; Van Dijk, Monique; Simons, Sinno H. P.; Tibboel, Dick. Expert Review of Clinical Pharmacology. 2017.

Perinatal and neonatal use of paracetamol for pain relief

Allegaert, Karel; van den Anker, John N.. Seminars in Fetal & Neonatal Medicine. 2017.

Randomized Controlled Trial Comparing Different Single Doses of Intravenous Paracetamol for Placement of Peripherally Inserted Central Catheters in Preterm Infants.

Roofthooft DWE; Simons SHP; van Lingen RA; Tibboel D; van den Anker JN; Reiss IKH; van Dijk M. Neonatology. 2017.

The amikacin research program: a stepwise approach to validate dosing regimens in neonates

Smits, Anne; Kulo, Aida; van den Anker, John; Allegaert, Karel. Expert opinion on drug metabolism & toxicology. 2017.

The Potential Role of Fosfomycin in Neonatal Sepsis Caused by Multidrug-Resistant Bacteria

Li, Grace; Bielicki, Julia; Hope, William; van den Anker, John; Sharland, Mike; Standing, Joseph F.; Heath, Paul T.. Drugs. 2017.

Therapeutic Drug Monitoring in Neonates: What Makes them Unique?

Mian P; Flint RB; Tibboel D; van den Anker JN; Allegaert K; Koch BCP. Current Pharmaceutical Design. 2017.

Therapeutic Drug Monitoring of Antibacterial Agents in the NICU

van den Anker, J. N.. Neonatology. 2017.

Use of Fentanyl in Adolescents with Clinically Severe Obesity Undergoing Bariatric Surgery: A Pilot Study.

Vaughns JD; Ziesenitz VC; Williams EF; Mushtaq A; Bachmann R; Skopp G; Weiss J; Mikus G; van den Anker JN. Paediatric drugs. 2017.

Valproic acid-induced hyperammonemic encephalopathy in a full-term neonate: a brief review and case report

Pokorna, Pavla; Hronova, Karolina; Sima, Martin; Slanar, Ondrej; Klement, Petr; van den Anker, John N.; Tibboel, Dick. European Journal of Clinical Pharmacology. 2017.

Waiting 2 minutes after sucrose administration-unnecessary?

Meesters N; Simons S; van Rosmalen J; Reiss I; van den Anker J; van Dijk M. Archives of Disease in Childhood: Fetal and Neonatal Edition. 2017.

Waiting 2 minutes after sucrose administration-unnecessary?

Meesters N; Simons S; van Rosmalen J; Reiss I; van den Anker J; van Dijk M. Archives of Disease in Childhood: Fetal and Neonatal Edition. 2017.

Acetaminophen to Prevent Symptomatic Patent Ductus Arteriosus: Another Drug Bites the Dust?

van den Anker JN; Allegaert K. Journal of Pediatrics. 2016.

A Mechanism to Explain Ototoxicity in Neonates Exposed to Bumetamide: Lessons to Help Improve Future Product Development in Neonates.

Allegaert K; Lahav A; van den Anker JN. Paediatric drugs. 2016.

Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.

Rodieux F; Gotta V; Pfister M; van den Anker JN. Journal of Clinical Pharmacology. 2016.

Characterizing and Forecasting Individual Weight Changes in Term Neonates.

Wilbaux M; Kasser S; Wellmann S; Lapaire O; van den Anker JN; Pfister M. Journal of Pediatrics. 2016.

Current Use of mTOR Inhibitors for the Treatment of Subependymal Giant Cell Astrocytomas and Epilepsy in Patients with TSC.

Jancic J; Duric V; Ivancevic N; Nikolic B; van den Anker JN; Samardzic J. Current Medicinal Chemistry. 2016.

Different Vancomycin Immunoassays Contribute to the Variability in Vancomycin Trough Measurements in Neonates.

Samardzic J; Smits A; Spriet I; Soldatovic I; Atkinson A; Bajcetic M; Van Den Anker JN; Allegaert K. BioMed Research International. 2016.

Erratum to: A Mechanism to Explain Ototoxicity in Neonates Exposed to Bumetanide: Lessons to Help Improve Future Product Development in Neonates.

Allegaert K; Lahav A; van den Anker JN. Paediatric drugs. 2016.

Evidence-Based Use of α-2 Agonists for Sedation in the PICU: From Fiction to Facts?

van den Anker JN; Allegaert K. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2016.

Impaired Neurodevelopmental Outcomes in Very Preterm Infants: Much Too Easy to Blame It Just on Morphine!

van den Anker JN; van Dijk M; Tibboel D. Journal of Pediatrics. 2016.

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen.

van Rongen A; Välitalo PAJ; Peeters MYM; Boerma D; Huisman FW; van Ramshorst B; van Dongen EPA; van den Anker JN; Knibbe CAJ. Clinical Pharmacokinetics. 2016.

Multiple Sclerosis in Pediatrics: Current Concepts and Treatment Options.

Jancic J; Nikolic B; Ivancevic N; Djuric V; Zaletel I; Stevanovic D; Peric S; van den Anker JN; Samardzic J. Neurology and therapy. 2016.

Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent-Metabolite Population Pharmacokinetic Model.

Cook SF; Stockmann C; Samiee-Zafarghandy S; King AD; Deutsch N; Williams EF; Wilkins DG; Sherwin CM; van den Anker JN. Clinical Pharmacokinetics. 2016.

Neonatal pain management: still in search for the Holy Grail.

Allegaert K; van den Anker JN. International Journal of Clinical Pharmacology and Therapeutics. 2016.

Neonatal withdrawal syndrome: reaching epidemic proportions across the globe.

Allegaert K; van den Anker JN. Archives of Disease in Childhood: Fetal and Neonatal Edition. 2016.

Pediatric Clinical Pharmacology of Voriconazole: Role of Pharmacokinetic/Pharmacodynamic Modeling in Pharmacotherapy.

Kadam RS; Van Den Anker JN. Clinical Pharmacokinetics. 2016.

Pharmacokinetic models of morphine and its metabolites in neonates:: Systematic comparisons of models from the literature, and development of a new meta-model.

Knøsgaard KR; Foster DJ; Kreilgaard M; Sverrisdóttir E; Upton RN; van den Anker JN. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016.

Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates.

Wilbaux M; Fuchs A; Samardzic J; Rodieux F; Csajka C; Allegaert K; van den Anker JN; Pfister M. Journal of Clinical Pharmacology. 2016.

Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms.

Shoji K; Bradley JS; Reed MD; van den Anker JN; Domonoske C; Capparelli EV. Antimicrobial Agents and Chemotherapy. 2016.

Population Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) in Preterm and Term Neonates: Model Development and External Evaluation.

Cook SF; Roberts JK; Samiee-Zafarghandy S; Stockmann C; King AD; Deutsch N; Williams EF; Allegaert K; Wilkins DG; Sherwin CM; van den Anker JN. Clinical Pharmacokinetics. 2016.

Possible effects of repeated exposure to ibuprofen and acetaminophen on the intestinal immune response in young infants.

Langhendries JP; Allegaert K; Van Den Anker JN; Veyckemans F; Smets F. MEDICAL HYPOTHESES. 2016.

Quantitative clinical pharmacology practice for optimal use of antibiotics during the neonatal period.

Samardzic J; Allegaert K; Wilbaux M; Pfister M; van den Anker JN. Expert opinion on drug metabolism & toxicology. 2016.

Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.

Hathout Y; Conklin LS; Seol H; Gordish-Dressman H; Brown KJ; Morgenroth LP; Nagaraju K; Heier CR; Damsker JM; van den Anker JN; Henricson E; Clemens PR; Mah JK; McDonald C; Hoffman EP. Scientific Reports. 2016.

Sildenafil and retinopathy of prematurity risk in very low birth weight infants.

Samiee-Zafarghandy S; van den Anker JN; Laughon MM; Clark RH; Smith PB; Hornik CP; Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee. Journal of Perinatology. 2016.

Therapeutic Drug Monitoring for Anti-infective Agents in Pediatrics: The Way Forward

Ritz N.; Bielicki J.; Pfister M.; Van Den Anker J.. Pediatric Infectious Disease Journal. 2016.

Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling.

Janssen EJ; Välitalo PA; Allegaert K; de Cock RF; Simons SH; Sherwin CM; Mouton JW; van den Anker JN; Knibbe CA. Antimicrobial Agents and Chemotherapy. 2016.

Treating Pain in Preterm Infants: Moving from Opioids to Acetaminophen.

van den Anker JN; Allegaert K. Journal of Pediatrics. 2016.

Unexplained peripheral neuropathic pain and/or stroke

Rodieux F.; Pfister M.; Van Den Anker J.; Rohrbach M.; Schuknecht B.; Gaspert A.; Palla A.; Nowak A.. Swiss Archives of Neurology, Psychiatry and Psychotherapy. 2016.

Unexplained peripheral neuropathic pain and/or stroke; especially in young patients - think about Fabry disease

Rodieux,F; Pfister,M; van den Anker,J; Rohrbach,M; Schuknecht,B; Gaspert,A; Palla,A; Nowak,A. . 2016.

[Understanding and reducing the risk of adverse drug reactions in pediatric patients].

Gotta V; van den Anker J; Pfister M. Therapeutische Umschau. 2015.

Adverse drug reactions in neonates and infants: a population-tailored approach is needed.

Allegaert K; van den Anker JN. British Journal of Clinical Pharmacology. 2015.

Availability of Oral Formulations Labeled for Use in Young Children in Serbia, Germany and the USA.

Bajcetic M; Kearns GL; Jovanovic I; Brajovic M; van den Anker JN. Current Pharmaceutical Design. 2015.

Benzodiazepine Prescribing in Older Adults in U.S. Ambulatory Clinics and Emergency Departments (2001-10).

Marra EM; Mazer-Amirshahi M; Brooks G; van den Anker J; May L; Pines JM. Journal of the American Geriatrics Society. 2015.

Clinical Pharmacology of Frequently Used Intravenous Drugs During Bariatric Surgery in Adolescents.

Vaughns JD; Ziesenitz VC; van den Anker JN. Current Pharmaceutical Design. 2015.

Cystatin C in newborns: a promising renal biomarker in search for standardization and validation.

Allegaert K; Mekahli D; van den Anker J. Journal of Maternal-Fetal and Neonatal Medicine. 2015.

Dosing Guidelines of Aminoglycosides in Neonates: A Balance Between Physiology and Feasibility.

Allegaert K; Cossey V; van den Anker JN. Current Pharmaceutical Design. 2015.

Early Inhaled Budesonide for the Prevention of Bronchopulmonary Dysplasia

Bassler, Dirk; Plavka, Richard; Shinwell, Eric S.; Hallman, Mikko; Jarreau, Pierre-Henri; Carnielli, Virgilio; Van den Anker, Johannes N.; Meisner, Christoph; Engel, Corinna; Schwab, Matthias; Halliday, Henry L.; Poets, Christian F.. New England Journal of Medicine. 2015.

Editorial: Neonatal and Pediatric Clinical Pharmacology.

van den Anker JN. Current Pharmaceutical Design. 2015.

Effect of Kidney Function on Drug Kinetics and Dosing in Neonates, Infants, and Children.

Rodieux F; Wilbaux M; van den Anker JN; Pfister M. Clinical Pharmacokinetics. 2015.

Elusive sources of variability of dystrophin rescue by exon skipping.

Vila MC; Klimek MB; Novak JS; Rayavarapu S; Uaesoontrachoon K; Boehler JF; Fiorillo AA; Hogarth MW; Zhang A; Shaughnessy C; Gordish-Dressman H; Burki U; Straub V; Lu QL; Partridge TA; Brown KJ; Hathout Y; van den Anker J; Hoffman EP; Nagaraju K. Skeletal Muscle. 2015.

Fluconazole prophylaxis in neonates.

Pansieri C; Pandolfini C; Jacqz-Aigrain E; van den Anker J; Bonati M. Archives of Disease in Childhood. 2015.

How to Improve the Safe and Effective Use of Doxorubicin in Children with Cancer.

van den Anker JN. Clinical Pharmacokinetics. 2015.

How to use vancomycin optimally in neonates: remaining questions.

Jacqz-Aigrain E; Leroux S; Zhao W; van den Anker JN; Sharland M. Expert Review of Clinical Pharmacology. 2015.

Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

Roofthooft, Daniella W. E.; van Beynum, Ingrid M.; de Klerk, Johan C. A.; van Dijk, Monique; van den Anker, John N.; Reiss, Irwin K. M.; Tibboel, Dick; Simons, Sinno H. P.. European journal of pediatrics. 2015.

Neonatal drug therapy: The first frontier of therapeutics for children.

Allegaert K; van den Anker J. Clinical Pharmacology and Therapeutics. 2015.

Neonatal Formulations: The Need for a Tailored, Knowledge Driven Approach.

Allegaert K; Cosaert K; van den Anker JN. Current Pharmaceutical Design. 2015.

Novel model-based dosing guidelines for gentamicin and tobramycin in preterm and term neonates.

Valitalo PA; van den Anker JN; Allegaert K; de Cock RF; de Hoog M; Simons SH; Mouton JW; Knibbe CA. Journal of Antimicrobial Chemotherapy. 2015.

Pharmacokinetic Studies in Neonates: The Utility of an Opportunistic Sampling Design.

Leroux S; Turner MA; Guellec CB; Hill H; van den Anker JN; Kearns GL; Jacqz-Aigrain E; Zhao W; TINN (Treat Infections in NeoNates) and GRiP (Global Research in Paediatrics) Consortiums. Clinical Pharmacokinetics. 2015.

Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents.

van Rongen A; Vaughns JD; Moorthy GS; Barrett JS; Knibbe CA; van den Anker JN. British Journal of Clinical Pharmacology. 2015.

Safety of milrinone use in neonatal intensive care units.

Samiee-Zafarghandy S; Raman SR; van den Anker JN; McHutchison K; Hornik CP; Clark RH; Brian Smith P; Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. Early Human Development. 2015.

Safety of milrinone use in neonatal intensive care units.

Samiee-Zafarghandy S; Raman SR; van den Anker JN; McHutchison K; Hornik CP; Clark RH; Brian Smith P; Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. Early Human Development. 2015.

Sedation in the neonatal intensive care unit: International practice

Allegaert K.; Van Den Anker J.. . 2015.

Simultaneous quantification of acetaminophen and five acetaminophen metabolites in human plasma and urine by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry: Method validation and application to a neonatal pharmacokinetic study.

Cook SF; King AD; van den Anker JN; Wilkins DG. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2015.

The Impact of Hypothermia on the Pharmacokinetics of Drugs Used in Neonates and Young Infants.

Pokorna P; Wildschut ED; Vobruba V; van den Anker JN; Tibboel D. Current Pharmaceutical Design. 2015.

The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse.

Zhang A; Uaesoontrachoon K; Shaughnessy C; Das JR; Rayavarapu S; Brown KJ; Ray PE; Nagaraju K; van den Anker JN; Hoffman EP; Hathout Y. Toxicology reports. 2015.

Use of Enoxaparin in Obese Adolescents During Bariatric Surgery--a Pilot Study.

Mushtaq A; Vaughns JD; Ziesenitz VC; Nadler EP; van den Anker JN. Obesity Surgery. 2015.

A Delphi process to optimize quality and performance of drug evaluation in neonates.

Legrand F; Boulkedid R; Elie V; Leroux S; Valls E; Valls-i-Soler A; Van den Anker JN; Jacqz-Aigrain E. PLoS ONE. 2014.

A neonatal amikacin covariate model can be used to predict ontogeny of other drugs eliminated through glomerular filtration in neonates.

De Cock RF; Allegaert K; Sherwin CM; Nielsen EI; de Hoog M; van den Anker JN; Danhof M; Knibbe CA. Pharmaceutical Research. 2014.

Best pharmaceuticals for children: how far have we come?

Mazer-Amirshahi M; van den Anker J. CURR THER RES CLIN E. 2014.

Clinical pharmacology in neonates: small size, huge variability.

Allegaert K; van den Anker JN. Neonatology. 2014.

Commentary: Continuous infusion of vancomycin in neonates: to use or not to use remains the question.

Ward RM; Allegaert K; de Groot R; van den Anker JN. Pediatric Infectious Disease Journal. 2014.

Critical drug shortages: implications for emergency medicine.

Mazer-Amirshahi M; Pourmand A; Singer S; Pines JM; van den Anker J. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2014.

Current Therapeutic Research is Now Indexed on PubMed.

van den Anker JN; Allegaert K; Kraft WK. CURR THER RES CLIN E. 2014.

Emerging Biomarkers and Metabolomics for Assessing Toxic Nephropathy and Acute Kidney Injury (AKI) in Neonatology

Mussap, M.; Noto, A.; Fanos, V.; Van den Anker, J. N.. Biomed Res Int. 2014.

Enzymatic isotope dilution mass spectrometry (IDMS) traceable serum creatinine is preferable over Jaffe in neonates and young infants.

Allegaert K; Pauwels S; Smits A; Crèvecoeur K; van den Anker J; Mekahli D; Vermeersch P. Clinical Chemistry and Laboratory Medicine. 2014.

First dose in neonates: are juvenile mice, adults and in vitro-in silico data predictive of neonatal pharmacokinetics of fluconazole.

Zhao W; Le Guellec C; Benjamin DK Jr; Hope WW; Bourgeois T; Watt KM; van den Anker JN; Matrot B; Saxen H; Hoppu K; Manzoni P; Jacqz-Aigrain E. Clinical Pharmacokinetics. 2014.

How to optimize the evaluation and use of antibiotics in neonates.

van den Anker JN. Early Human Development. 2014.

In reply.

Mazer-Amirshahi M; Mullins PM; Rasooly I; van den Anker J; Pines JM. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2014.

Intestinal fatty-acid binding protein and metronidazole response in premature infants.

Sampson MR; Bloom BT; Arrieta A; Capparelli E; Benjamin DK Jr; Smith PB; Kearns GL; van den Anker J; Cohen-Wolkowiez M. Journal of neonatal-perinatal medicine. 2014.

Neonatal abstinence syndrome: on the evidence to add breastfeeding to any clinical pathway.

Allegaert K; van den Anker JN. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2014.

Neonatal clinical pharmacology.

Allegaert K; van de Velde M; van den Anker J. Paediatric anaesthesia. 2014.

Off-label use of drugs in children.

Frattarelli DA; Galinkin JL; Green TP; Johnson TD; Neville KA; Paul IM; Van Den Anker JN; American Academy of Pediatrics Committee on Drugs. Pediatrics. 2014.

Perinatal pharmacology.

Allegaert K; Fanos V; van den Anker JN; Laër S. BioMed Research International. 2014.

Pharmacologic prevention of perinatal HIV infection.

Rakhmanina NY; van den Anker JN. Early Human Development. 2014.

Population pharmacokinetics of ciprofloxacin in neonates and young infants less than three months of age.

Zhao W; Hill H; Le Guellec C; Neal T; Mahoney S; Paulus S; Castellan C; Kassai B; van den Anker JN; Kearns GL; Turner MA; Jacqz-Aigrain E; TINN Consortium. Antimicrobial Agents and Chemotherapy. 2014.

Rising opioid prescribing in adult U.S. emergency department visits: 2001-2010.

Mazer-Amirshahi M; Mullins PM; Rasooly I; van den Anker J; Pines JM. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2014.

Rising rates of proton pump inhibitor prescribing in US emergency departments.

Mazer-Amirshahi M; Mullins PM; van den Anker J; Meltzer A; Pines JM. The American journal of emergency medicine. 2014.

Safety of sildenafil in infants*.

Samiee-Zafarghandy S; Smith PB; van den Anker JN. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2014.

Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtration.

De Cock RF; Allegaert K; Brussee JM; Sherwin CM; Mulla H; de Hoog M; van den Anker JN; Danhof M; Knibbe CA. Pharmaceutical Research. 2014.

Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.

Bhattacharyya S; Yan K; Pence L; Simpson PM; Gill P; Letzig LG; Beger RD; Sullivan JE; Kearns GL; Reed MD; Marshall JD; Van Den Anker JN; James LP. Biomarkers in Medicine. 2014.

The addition of tramadol to a standard i.v. acetaminophen/morphine analgesia protocol in neonates: purposeful or just polypharmacy?

Allegaert K; van den Anker JN. Paediatric anaesthesia. 2014.

The impact of pediatric labeling changes on prescribing patterns of cough and cold medications.

Mazer-Amirshahi M; Rasooly I; Brooks G; Pines J; May L; van den Anker J. Journal of Pediatrics. 2014.

The impact of race on analgesia use among pediatric emergency department patients.

Rasooly IR; Mullins PM; Mazer-Amirshahi M; van den Anker J; Pines JM. Journal of Pediatrics. 2014.

The impact of therapeutic drug monitoring in neonatal clinical pharmacology.

van den Anker JN. Clinical Biochemistry. 2014.

Topical nitroglycerin in neonates with tissue injury: A case report and review of the literature.

Samiee-Zafarghandy S; van den Anker JN; Ben Fadel N. Paediatrics & Child Health. 2014.

Trends in opioid analgesic use for headaches in US emergency departments.

Mazer-Amirshahi M; Dewey K; Mullins PM; van den Anker J; Pines JM; Perrone J; Nelson L. The American journal of emergency medicine. 2014.

Trends in paediatric clinical pharmacology data in US pharmaceutical labelling.

Samiee-Zafarghandy S; Mazer-Amirshahi M; van den Anker JN. Archives of Disease in Childhood. 2014.

Trends in pregnancy labeling and data quality for US-approved pharmaceuticals.

Mazer-Amirshahi M; Samiee-Zafarghandy S; Gray G; van den Anker JN. American journal of obstetrics and gynecology. 2014.

Trends in prescription opioid use in pediatric emergency department patients.

Mazer-Amirshahi M; Mullins PM; Rasooly IR; van den Anker J; Pines JM. Pediatric emergency care. 2014.

Why is there no morphine concentration-response curve for acute pain?

Anderson BJ; van den Anker J. Paediatric anaesthesia. 2014.

Aminoglycosides and ototoxicity in neonates: is there a relation with serum concentrations?

Samiee-Zafarghandy S; van den Anker JN. International Journal of Clinical Pharmacology and Therapeutics. 2013.

Impact of CYP3A and ABCB1 polymorphisms on the pharmacokinetics and pharmacodynamics of fentanyl.

Ziesenitz VC; van den Anker JN. International Journal of Clinical Pharmacology and Therapeutics. 2013.

Is there really a need to adjust gentamicin dosing in neonates treated with hypothermia?

Samiee S; van den Anker J. Therapeutic drug monitoring. 2013.

Physicochemical and Structural Properties Regulating Placental Drug Transfer

Plonait S.L.; Nau H.. Fetal and Neonatal Physiology: Third Edition. 2003.