Departement
Klinische Forschung
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Publications Hemkens Lars G.

Association of the COVID-19 outbreak with acute stroke care in Switzerland.

De Marchis GM; Wright PR; Michel P; Strambo D; Carrera E; Dirren E; Luft AR; Wegener S; Cereda CW; Kägi G; Vehoff J; Gensicke H; Lyrer P; Nedeltchev K; Khales T; Bolognese M; Salmen S; Sturzenegger R; Bonvin C; Berger C; Schelosky L; Mono ML; Rodic B; von Reding A; Schwegler G; Tarnutzer AA; Medlin F; Humm AM; Peters N; Beyeler M; Kriemler L; Bervini D; Fandino J; Hemkens LG; Mordasini P; Arnold M; Fischer U; Bonati LH; Swiss Stroke Registry Investigators.. European journal of neurology. 2022.

A systematic survey of methods guidance suggests areas for improvement regarding access, development, and transparency.

Hirt J; Ewald H; Lawson DO; Hemkens LG; Briel M; Schandelmaier S. Journal of clinical epidemiology. 2022.

Central diabetes insipidus from a patient's perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey

Atila C.; Loughrey P.B.; Garrahy A.; Winzeler B.; Refardt J.; Gildroy P.; Hamza M.; Pal A.; Verbalis J.G.; Thompson C.J.; Hemkens L.G.; Hunter S.J.; Sherlock M.; Levy M.J.; Karavitaki N.; Newell-Price J.; Wass J.A.H.; Christ-Crain M.. The lancet. Diabetes & endocrinology. 2022.

Characteristics and survival of patients with cancer with intended off-label use-a cohort study.

Schmitt AM; Walter M; Herbrand AK; Jörger M; Moffa G; Novak U; Hemkens L; Kasenda B. BMJ Open. 2022.

Clinical trial research agenda on COVID-19 - the first two years in Germany and beyond.

Hirt J; Janiaud P; Hemkens LG. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 2022.

High quality (certainty) evidence changes less often than low-quality evidence, but the magnitude of effect size does not systematically differ between studies with low versus high-quality evidence.

Djulbegovic B; Ahmed MM; Hozo I; Koletsi D; Hemkens L; Price A; Riera R; Nadanovsky P; Dos Santos APP; Melo D; Pathak R; Pacheco RL; Fontes LE; Miranda E; Nunan D. Journal of evaluation in clinical practice. 2022.

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.

Speich B; Gryaznov D; Busse JW; Gloy VL; Lohner S; Klatte K; Taji Heravi A; Ghosh N; Lee H; Mansouri A; Marian IR; Saccilotto R; Nury E; Kasenda B; Ojeda-Ruiz E; Schandelmaier S; Tomonaga Y; Amstutz A; Pauli-Magnus C; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Wong J; Chow N; Hong PJ; Mc Cord-De Iaco K; Sricharoenchai S; Agarwal A; Schwenkglenks M; Hemkens LG; von Elm E; Copsey B; Griessbach AN; Schönenberger C; Mertz D; Blümle A; von Niederhäusern B; Hopewell S; Odutayo A; Briel M. PLoS medicine. 2022.

Randomized trials on non-pharmaceutical interventions for COVID-19: a scoping review.

Hirt J; Janiaud P; Hemkens LG. BMJ evidence-based medicine. 2022.

Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit Recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE).

Gryaznov D; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Blümle A; Schandelmaier S; Mertz D; Odutayo A; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Lohner S; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Taji Heravi A; Wong J; Chow N; Hong P; McCord-De Iaco KA; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens L; Hopewell S; Von Elm E; Briel M. BMJ Open. 2022.

Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: A systematic review

Hirt J.; Janiaud P.; Gloy V.L.; Schandelmaier S.; Pereira T.V.; Contopoulos-Ioannidis D.; Goodman S.N.; Ioannidis J.; Munkholm K.; Hemkens L.G.. Archives of Disease in Childhood. 2022.

Searching two or more databases decreased the risk of missing relevant studies: a metaresearch study.

Ewald H; Klerings I; Wagner G; Heise TL; Stratil JM; Lhachimi SK; Hemkens LG; Gartlehner G; Armijo-Olivo S; Nussbaumer-Streit B. Journal of clinical epidemiology. 2022.

Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data.

Hemmig AK; Gozzoli D; Werlen L; Ewald H; Aschwanden M; Blockmans D; Brouwer E; Buchanan RRC; Camellino D; Campochiaro C; Cimmino MA; Corominas H; Gloy V; Henckaerts L; Kyburz D; Moya-Alvarado P; Owen CE; Stegert M; Tomelleri A; van Sleen Y; Yamashita H; Imfeld S; Berger CT; Hemkens LG; Daikeler T. Seminars in arthritis and rheumatism. 2022.

Ten simple rules for good research practice.

Schwab S; Janiaud P; Dayan M; Amrhein V; Panczak R; Palagi PM; Hemkens LG; Ramon M; Rothen N; Senn S; Furrer E; Held L. . 2022.

[Benefit assessment of digital health applications-challenges and opportunities].

Hemkens LG. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2021.

Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials.

Axfors C; Janiaud P; Schmitt AM; Van't Hooft J; Smith ER; Haber NA; Abayomi A; Abduljalil M; Abdulrahman A; Acosta-Ampudia Y; Aguilar-Guisado M; Al-Beidh F; Alejandria MM; Alfonso RN; Ali M; AlQahtani M; AlZamrooni A; Anaya JM; Ang MAC; Aomar IF; Argumanis LE; Averyanov A; Baklaushev VP; Balionis O; Benfield T; Berry S; Birocco N; Bonifacio LB; Bowen AC; Bown A; Cabello-Gutierrez C; Camacho B; Camacho-Ortiz A; Campbell-Lee S; Cao DH; Cardesa A; Carnate JM; Castillo GJJ; Cavallo R; Chowdhury FR; Chowdhury FUH; Ciccone G; Cingolani A; Climacosa FMM; Compernolle V; Cortez CFN; Costa Neto A; D'Antico S; Daly J; Danielle F; Davis JS; De Rosa FG; Denholm JT; Denkinger CM; Desmecht D; Díaz-Coronado JC; Díaz Ponce-Medrano JA; Donneau AF; Dumagay TE; Dunachie S; Dungog CC; Erinoso O; Escasa IMS; Estcourt LJ; Evans A; Evasan ALM; Fareli CJ; Fernandez-Sanchez V; Galassi C; Gallo JE; Garcia PJ; Garcia PL; Garcia JA; Garigliany M; Garza-Gonzalez E; Gauiran DTV; Gaviria García PA; Giron-Gonzalez JA; Gómez-Almaguer D; Gordon AC; Gothot A; Grass Guaqueta JS; Green C; Grimaldi D; Hammond NE; Harvala H; Heralde FM; Herrick J; Higgins AM; Hills TE; Hines J; Holm K; Hoque A; Hoste E; Ignacio JM; Ivanov AV; Janssen M; Jennings JH; Jha V; King RAN; Kjeldsen-Kragh J; Klenerman P; Kotecha A; Krapp F; Labanca L; Laing E; Landin-Olsson M; Laterre PF; Lim LL; Lim J; Ljungquist O; Llaca-Díaz JM; López-Robles C; López-Cárdenas S; Lopez-Plaza I; Lucero JAC; Lundgren M; Macías J; Maganito SC; Malundo AFG; Manrique RD; Manzini PM; Marcos M; Marquez I; Martínez-Marcos FJ; Mata AM; McArthur CJ; McQuilten ZK; McVerry BJ; Menon DK; Meyfroidt G; Mirasol MAL; Misset B; Molton JS; Mondragon AV; Monsalve DM; Moradi Choghakabodi P; Morpeth SC; Mouncey PR; Moutschen M; Müller-Tidow C; Murphy E; Najdovski T; Nichol AD; Nielsen H; Novak RM; O'Sullivan MVN; Olalla J; Osibogun A; Osikomaiya B; Oyonarte S; Pardo-Oviedo JM; Patel MC; Paterson DL; Peña-Perez CA; Perez-Calatayud AA; Pérez-Alba E; Perkina A; Perry N; Pouladzadeh M; Poyato I; Price DJ; Quero AKH; Rahman MM; Rahman MS; Ramesh M; Ramírez-Santana C; Rasmussen M; Rees MA; Rego E; Roberts JA; Roberts DJ; Rodríguez Y; Rodríguez-Baño J; Rogers BA; Rojas M; Romero A; Rowan KM; Saccona F; Safdarian M; Santos MCM; Sasadeusz J; Scozzari G; Shankar-Hari M; Sharma G; Snelling T; Soto A; Tagayuna PY; Tang A; Tatem G; Teofili L; Tong SYC; Turgeon AF; Veloso JD; Venkatesh B; Ventura-Enriquez Y; Webb SA; Wiese L; Wikén C; Wood EM; Yusubalieva GM; Zacharowski K; Zarychanski R; Khanna N; Moher D; Goodman SN; Ioannidis JPA; Hemkens LG. BMC INFECTIOUS DISEASES. 2021.

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis.

Janiaud P; Axfors C; Schmitt AM; Gloy V; Ebrahimi F; Hepprich M; Smith ER; Haber NA; Khanna N; Moher D; Goodman SN; Ioannidis JPA; Hemkens LG. JAMA. 2021.

Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs.

Herbrand AK; Schmitt AM; Briel M; Ewald H; Goldkuhle M; Diem S; Hoogkamer A; Joerger M; Moffa G; Novak U; Hemkens LG; Kasenda B. JAMA Network Open. 2021.

A study protocol for the development of a SPIRIT extension for trials conducted using cohorts and routinely collected data (SPIRIT-ROUTINE).

McCarthy M; O'Keeffe L; Williamson PR; Sydes MR; Farrin A; Lugg-Widger F; Davies G; Avery K; Chan AW; Kwakkenbos L; Thombs BD; Watkins A; Hemkens LG; Gale C; Zwarenstein M; Langan SM; Thabane L; Juszczak E; Moher D; Kearney PM. HRB open research. 2021.

A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®.

Speich B; Chammartin F; Smith D; Stoeckle MP; Amico P; Eichenberger AL; Hasse B; Schuurmans MM; Müller T; Tamm M; Dickenmann M; Abela IA; Trkola A; Hirsch HH; Manuel O; Cavassini M; Hemkens LG; Briel M; Mueller NJ; Rauch A; Günthard HF; Koller MT; Bucher HC; Kusejko K; study groups from the Swiss HIV Cohort Study and the Swiss Transplant Cohort Study.. Trials. 2021.

Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Axfors C; Schmitt AM; Janiaud P; Van't Hooft J; Abd-Elsalam S; Abdo EF; Abella BS; Akram J; Amaravadi RK; Angus DC; Arabi YM; Azhar S; Baden LR; Baker AW; Belkhir L; Benfield T; Berrevoets MAH; Chen CP; Chen TC; Cheng SH; Cheng CY; Chung WS; Cohen YZ; Cowan LN; Dalgard O; de Almeida E Val FF; de Lacerda MVG; de Melo GC; Derde L; Dubee V; Elfakir A; Gordon AC; Hernandez-Cardenas CM; Hills T; Hoepelman AIM; Huang YW; Igau B; Jin R; Jurado-Camacho F; Khan KS; Kremsner PG; Kreuels B; Kuo CY; Le T; Lin YC; Lin WP; Lin TH; Lyngbakken MN; McArthur C; McVerry BJ; Meza-Meneses P; Monteiro WM; Morpeth SC; Mourad A; Mulligan MJ; Murthy S; Naggie S; Narayanasamy S; Nichol A; Novack LA; O'Brien SM; Okeke NL; Perez L; Perez-Padilla R; Perrin L; Remigio-Luna A; Rivera-Martinez NE; Rockhold FW; Rodriguez-Llamazares S; Rolfe R; Rosa R; Røsjø H; Sampaio VS; Seto TB; Shahzad M; Soliman S; Stout JE; Thirion-Romero I; Troxel AB; Tseng TY; Turner NA; Ulrich RJ; Walsh SR; Webb SA; Weehuizen JM; Velinova M; Wong HL; Wrenn R; Zampieri FG; Zhong W; Moher D; Goodman SN; Ioannidis JPA; Hemkens LG. . 2021.

Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials.

McLennan S; Nussbaumer-Streit B; Hemkens LG; Briel M. JAMA Network Open. 2021.

Challenges and Lessons Learned From COVID-19 Trials: Should We Be Doing Clinical Trials Differently?

Janiaud P; Hemkens LG; Ioannidis JPA. The Canadian journal of cardiology. 2021.

CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration.

Kwakkenbos L; Imran M; McCall SJ; McCord KA; Fröbert O; Hemkens LG; Zwarenstein M; Relton C; Rice DB; Langan SM; Benchimol EI; Thabane L; Campbell MK; Sampson M; Erlinge D; Verkooijen HM; Moher D; Boutron I; Ravaud P; Nicholl J; Uher R; Sauvé M; Fletcher J; Torgerson D; Gale C; Juszczak E; Thombs BD. BMJ (Clinical research ed.). 2021.

Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE).

Imran M; Kwakkenbos L; McCall SJ; McCord KA; Fröbert O; Hemkens LG; Zwarenstein M; Relton C; Rice DB; Langan SM; Benchimol EI; Thabane L; Campbell MK; Sampson M; Erlinge D; Verkooijen HM; Moher D; Boutron I; Ravaud P; Nicholl J; Uher R; Sauvé M; Fletcher J; Torgerson D; Gale C; Juszczak E; Thombs BD. BMJ Open. 2021.

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Axfors C; Schmitt AM; Janiaud P; Van't Hooft J; Abd-Elsalam S; Abdo EF; Abella BS; Akram J; Amaravadi RK; Angus DC; Arabi YM; Azhar S; Baden LR; Baker AW; Belkhir L; Benfield T; Berrevoets MAH; Chen CP; Chen TC; Cheng SH; Cheng CY; Chung WS; Cohen YZ; Cowan LN; Dalgard O; de Almeida E Val FF; de Lacerda MVG; de Melo GC; Derde L; Dubee V; Elfakir A; Gordon AC; Hernandez-Cardenas CM; Hills T; Hoepelman AIM; Huang YW; Igau B; Jin R; Jurado-Camacho F; Khan KS; Kremsner PG; Kreuels B; Kuo CY; Le T; Lin YC; Lin WP; Lin TH; Lyngbakken MN; McArthur C; McVerry BJ; Meza-Meneses P; Monteiro WM; Morpeth SC; Mourad A; Mulligan MJ; Murthy S; Naggie S; Narayanasamy S; Nichol A; Novack LA; O'Brien SM; Okeke NL; Perez L; Perez-Padilla R; Perrin L; Remigio-Luna A; Rivera-Martinez NE; Rockhold FW; Rodriguez-Llamazares S; Rolfe R; Rosa R; Røsjø H; Sampaio VS; Seto TB; Shahzad M; Soliman S; Stout JE; Thirion-Romero I; Troxel AB; Tseng TY; Turner NA; Ulrich RJ; Walsh SR; Webb SA; Weehuizen JM; Velinova M; Wong HL; Wrenn R; Zampieri FG; Zhong W; Moher D; Goodman SN; Ioannidis JPA; Hemkens LG. Nature Communications. 2021.

Prepectoral versus subpectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02/ PREPEC): a pragmatic, multicentre, randomised, superiority trial.

Kappos EA; Schulz A; Regan MM; Moffa G; Harder Y; Ribi K; Potter S; Pusic AL; Fehr MK; Hemkens LG; Holzbach T; Farhadi J; Simonson C; Knauer M; Verstappen R; Bucher HC; Zwahlen D; Zimmermann F; Schwenkglenks M; Mucklow R; Shaw J; Bjelic-Radisic V; Chiorescu A; Chun YS; Farah S; Xiaosong C; Nigard L; Kuemmel S; Reitsamer R; Hauschild M; Fulco I; Tausch C; Fischer T; Sarlos D; Constantinescu MA; Lupatsch JE; Fitzal F; Heil J; Matrai Z; de Boniface J; Kurzeder C; Haug M; Weber WP. BMJ Open. 2021.

Randomized COVID-19 vaccination rollout can offer direct real-world evidence.

Hemkens LG; Goodman SN. Journal of clinical epidemiology. 2021.

Recruitment and Results Reporting of COVID-19 Randomized Clinical Trials Registered in the First 100 Days of the Pandemic.

Janiaud P; Axfors C; Ioannidis JPA; Hemkens LG. JAMA Network Open. 2021.

Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study.

Lohner S; Gryaznov D; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Schandelmaier S; Mertz D; Odutayo A; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Heravi AT; Wong J; Chow N; Hong PJ; McCord K; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens LG; Hopewell S; von Elm E; Blümle A; Briel M. Journal of clinical epidemiology. 2021.

Reporting transparency and completeness in trials: Paper 1: Introduction - Better reporting for disruptive clinical trials using routinely collected data.

Hemkens LG; Juszczak E; Thombs BD. . 2021.

Reporting transparency and completeness in Trials: Paper 2 - reporting of randomised trials using registries was often inadequate and hindered the interpretation of results.

Mc Cord KA; Imran M; Rice DB; McCall SJ; Kwakkenbos L; Sampson M; Fröbert O; Gale C; Langan SM; Moher D; Relton C; Zwarenstein M; Juszczak E; Thombs BD; Hemkens LG; CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data Group.. Journal of clinical epidemiology. 2021.

Reporting transparency and completeness in trials: Paper 3 - trials conducted using administrative databases do not adequately report elements related to use of databases.

Imran M; Mc Cord K; McCall SJ; Kwakkenbos L; Sampson M; Fröbert O; Gale C; Hemkens LG; Langan SM; Moher D; Relton C; Zwarenstein M; Juszczak E; Thombs BD; CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data Group.. Journal of clinical epidemiology. 2021.

Reporting transparency and completeness in trials: Paper 4 - reporting of randomised controlled trials conducted using routinely collected electronic records - room for improvement.

McCall SJ; Imran M; Hemkens LG; Mc Cord K; Kwakkenbos L; Sampson M; Jawad S; Zwarenstein M; Relton C; Langan SM; Moher D; Fröbert O; Thombs BD; Gale C; Juszczak E; CONSORT Extension for Trials Conducted Using Cohorts and RoutinelyCollected Data Group.. Journal of clinical epidemiology. 2021.

Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study.

Mc Cord KA; Ewald H; Agarwal A; Glinz D; Aghlmandi S; Ioannidis JPA; Hemkens LG. BMJ (Clinical research ed.). 2021.

Abbreviated and comprehensive literature searches led to identical or very similar effect estimates: a meta-epidemiological study

Ewald H.; Klerings I.; Wagner G.; Heise T.L.; Dobrescu A.I.; Armijo-Olivo S.; Stratil J.M.; Lhachimi S.K.; Mittermayr T.; Gartlehner G.; Nussbaumer-Streit B.; Hemkens L.G.. Journal of clinical epidemiology. 2020.

A scoping review shows that several nonvalidated budget planning tools for randomized trials are available.

Speich B; Gloy V; Schur N; Ewald H; Hemkens LG; Schwenkglenks M; Briel M; MAking Randomized Trials Affordable (MARTA) Group.. Journal of clinical epidemiology. 2020.

Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey.

Schandelmaier S; Schmitt AM; Herbrand AK; Glinz D; Ewald H; Briel M; Guyatt GH; Hemkens LG; Kasenda B. BMJ Open. 2020.

Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016.

Ladanie A; Schmitt AM; Speich B; Naudet F; Agarwal A; Pereira TV; Sclafani F; Herbrand AK; Briel M; Martin-Liberal J; Schmid T; Ewald H; Ioannidis JPA; Bucher HC; Kasenda B; Hemkens LG. JAMA Network Open. 2020.

Commentary on Bertagnolli et al: Clinical trial designs with routinely collected real-world data—issues of data quality and beyond

Hemkens L.G.. Clinical Trials. 2020.

Consideration of confounding was suboptimal in the reporting of observational studies in psychiatry: a meta-epidemiological study.

Munkholm K; Faurholt-Jepsen M; Ioannidis JPA; Hemkens LG. Journal of clinical epidemiology. 2020.

Design, analysis and reporting of multi-arm trials and strategies to address multiple testing.

Odutayo A; Gryaznov D; Copsey B; Monk P; Speich B; Roberts C; Vadher K; Dutton P; Briel M; Hopewell S; Altman DG; ASPIRE study group.. International journal of epidemiology. 2020.

Knowledge gaps in oncoplastic breast surgery.

Weber WP; Morrow M; Boniface J; Pusic A; Montagna G; Kappos EA; Ritter M; Haug M; Kurzeder C; Saccilotto R; Schulz A; Benson J; Fitzal F; Matrai Z; Shaw J; Peeters MV; Potter S; Heil J; Oncoplastic Breast Consortium.. The Lancet Oncology. 2020.

Nonrandomized studies using causal-modeling may give different answers than RCTs: a meta-epidemiological study.

Ewald H; Ioannidis JPA; Ladanie A; Mc Cord K; Bucher HC; Hemkens LG. Journal of clinical epidemiology. 2020.

Online randomized controlled experiments at scale: lessons and extensions to medicine.

Kohavi R; Tang D; Xu Y; Hemkens LG; Ioannidis JPA. Trials. 2020.

Oral corticosteroids for post-infectious cough in adults: study protocol for a double-blind randomized placebo-controlled trial in Swiss family practices (OSPIC trial).

Merlo C; Essig S; Brancati-Badarau DO; Leuppi JD; Speich B; Erlanger TE; Hemkens LG; Zeller A. Trials. 2020.

Patient involvement to inform the design of a clinical trial in postbariatric hypoglycaemia.

Hepprich M; Donath MY; Hemkens LG. BMC Medical Research Methodology. 2020.

Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)-rationale and design for an international collaborative study.

Kasenda B; Liu J; Jiang Y; Gajewski B; Wu C; von Elm E; Schandelmaier S; Moffa G; Trelle S; Schmitt AM; Herbrand AK; Gloy V; Speich B; Hopewell S; Hemkens LG; Sluka C; McGill K; Meade M; Cook D; Lamontagne F; Tréluyer JM; Haidich AB; Ioannidis JPA; Treweek S; Briel M. Trials. 2020.

Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects.

Gryaznov D; Odutayo A; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Blümle A; Schandelmaier S; Mertz D; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Bischoff K; Wollmann K; Rehner L; Lohner S; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Heravi AT; Wong J; Chow N; Hong PJ; Cord KM; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens LG; Hopewell S; von Elm E; Briel M. Trials. 2020.

The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days

Hemkens L.G.; Janiaud P.; Axfors C.; van't Hooft J.; Saccilotto R.; Agarwal A.; Appenzeller-Herzog C.; Contopoulos-Ioannidis D.G.; Danchev V.; Dirnagl U.; Ewald H.; Gartlehner G.; Goodman S.N.; Haber N.A.; Ioannidis A.D.; Ioannidis J.P.A.; Lythgoe M.P.; Ma W.; Macleod M.; Malicki M.; Meerpohl J.J.; Min Y.; Moher D.; Nagavci B.; Naudet F.; Pauli-Magnus C.; O'Sullivan J.W.; Riedel N.; Roth J.A.; Sauermann M.; Schandelmaier S.; Schmitt A.M.; Speich B.; Williamson P.R.. F1000Research. 2020.

The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days.

Janiaud P; Axfors C; Van't Hooft J; Saccilotto R; Agarwal A; Appenzeller-Herzog C; Contopoulos-Ioannidis DG; Danchev V; Dirnagl U; Ewald H; Gartlehner G; Goodman SN; Haber NA; Ioannidis AD; Ioannidis JPA; Lythgoe MP; Ma W; Macleod M; Malički M; Meerpohl JJ; Min Y; Moher D; Nagavci B; Naudet F; Pauli-Magnus C; O'Sullivan JW; Riedel N; Roth JA; Sauermann M; Schandelmaier S; Schmitt AM; Speich B; Williamson PR; Hemkens LG. F1000Research. 2020.

Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project.

Herbrand AK; Schmitt AM; Briel M; Diem S; Ewald H; Hoogkamer A; Joerger M; Mc Cord KA; Novak U; Sricharoenchai S; Hemkens LG; Kasenda B. ESMO open. 2019.

Current use and costs of electronic health records for clinical trial research: a descriptive study.

Mc Cord KA; Ewald H; Ladanie A; Briel M; Speich B; Bucher HC; Hemkens LG; RCD for RCTs initiative and the Making Randomized Trials More Affordable Group.. CMAJ open. 2019.

Dopaminergic agents versus control for enhancing stroke recovery and rehabilitation

Engelter S.; Hemkens L.G.; Speich B.; Traenka C.. Cochrane Database of Systematic Reviews. 2019.

Effect of Combination l-Citrulline and Metformin Treatment on Motor Function in Patients With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.

Hafner P; Bonati U; Klein A; Rubino D; Gocheva V; Schmidt S; Schroeder J; Bernert G; Laugel V; Steinlin M; Capone A; Gloor M; Bieri O; Hemkens LG; Speich B; Zumbrunn T; Gueven N; Fischer D. JAMA Network Open. 2019.

Marginal structural models and other analyses allow multiple estimates of treatment effects in randomized clinical trials: Meta-epidemiological analysis.

Ewald H; Speich B; Ladanie A; Bucher HC; Ioannidis JPA; Hemkens LG. Journal of clinical epidemiology. 2019.

Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation.

Speich B; Schur N; Gryaznov D; von Niederhäusern B; Hemkens LG; Schandelmaier S; Amstutz A; Kasenda B; Pauli-Magnus C; Ojeda-Ruiz E; Tomonaga Y; McCord K; Nordmann A; von Elm E; Briel M; Schwenkglenks M; a collaboration of the MARTA (MAking Randomized Trials Affordable) and ASPIRE (Adherence to Standard Protocol Items: REcommendations for interventional trials) Study Groups.. PLoS One. 2019.

Rituximab in primary central nervous system lymphoma-A systematic review and meta-analysis.

Schmitt AM; Herbrand AK; Fox CP; Bakunina K; Bromberg JEC; Cwynarski K; Doorduijn JK; Ferreri AJM; Illerhaus G; Issa S; Schorb E; Zucca E; Hemkens LG; Schandelmaier S; Kasenda B. Hematological oncology. 2019.

Single-dose versus 3-day cotrimoxazole prophylaxis in transurethral resection or greenlight laser vaporisation of the prostate: study protocol for a multicentre randomised placebo controlled non-inferiority trial (CITrUS trial).

Speich B; Bausch K; Roth JA; Hemkens LG; Ewald H; Vogt DR; Bruni N; Deuster S; Seifert HH; Widmer AF. Trials. 2019.

Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies.

Ladanie A; Speich B; Briel M; Sclafani F; Bucher HC; Agarwal A; Ioannidis JPA; Pereira TV; Kasenda B; Hemkens LG. Journal of clinical epidemiology. 2019.

The Guidelines for Reporting of Studies Conducted Using Observational Routinely Collected Health Data Statement for Pharmacoepidemiology (RECORD-PE) La déclaration RECORD-PE (Reporting of Studies Conducted Using Observational Routinely Collected Health Data Statement for Pharmacoepdemiology) : directives pour la communication des études realisées à partir de données de santé observationelles collectées en routine en pharmacoépidémiologie

Langan S.M.; Schmidt S.A.J.; Wing K.; Ehrenstein V.; Nicholls S.G.; Filion K.B.; Klungel O.; Petersen I.; SOrensen H.T.; Dixon W.G.; Guttmann A.; Harron K.; Hemkens L.G.; Moher D.; Schneeweiss S.; Smeeth L.; Sturkenboom M.; Von Elm E.; Wang S.V.; Benchimol E.I.. CMAJ. 2019.

The REporting of studies Conducted using Observational Routinely collected health Data (RECORD) statement: Guidelines for the reporting of studies conducted based on routinely collected health data La déclaration RECORD (Reporting of Studies Conducted Using Observational Routinely Collected Health Data): Directives pour la communication des études réalisées à partir de données de santé collectées en routine

Benchimol E.I.; Smeeth L.; Guttmann A.; Harron K.; Moher D.; Petersen I.; SOrensen H.T.; Januel J.; Von Elm E.; Langan S.M.; Altman D.; De Klerk N.; Hemkens L.G.; Henry D.; Le Pogam M.; Manuel D.; Patrick K.; Perel P.; Romano P.S.; Tugwell P.; Warren J.; Weber W.; Winker M.. CMAJ. 2019.

Using electronic health records for clinical trials: Where do we stand and where can we go?

Mc Cord KA; Hemkens LG. CMAJ. 2019.

Abbreviated literature searches were viable alternatives to comprehensive searches: a meta-epidemiological study.

Nussbaumer-Streit B; Klerings I; Wagner G; Heise TL; Dobrescu AI; Armijo-Olivo S; Stratil JM; Persad E; Lhachimi SK; Van Noord MG; Mittermayr T; Zeeb H; Hemkens L; Gartlehner G. Journal of clinical epidemiology. 2018.

How Routinely Collected Data for Randomized Trials Provide Long-term Randomized Real-World Evidence.

Hemkens LG. JAMA Network Open. 2018.

How to use FDA drug approval documents for evidence syntheses.

Ladanie A; Ewald H; Kasenda B; Hemkens LG. BMJ (Clinical research ed.). 2018.

Interpretation of epidemiologic studies very often lacked adequate consideration of confounding

Hemkens L.G.; Ewald H.; Naudet F.; Ladanie A.; Shaw J.G.; Sajeev G.; Ioannidis J.P.A.. Journal of clinical epidemiology. 2018.

Off-label prescription: experience is a gloomy lantern that does not even illuminate its bearer. Author response

Ladanie A.; Ioannidis J.P.A.; Stafford R.S.; Ewald H.; Bucher H.C.; Hemkens L.G.; Hemkens L.G.. Journal of clinical epidemiology. 2018.

Off-label treatments were not consistently better or worse than approved drug treatments in randomized trials.

Ladanie A; Ioannidis JPA; Stafford RS; Ewald H; Bucher HC; Hemkens LG. Journal of clinical epidemiology. 2018.

Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data

Kwakkenbos L.; Imran M.; McCord K.A.; Sampson M.; Frobert O.; Gale C.; Hemkens L.G.; Langan S.M.; Moher D.; Relton C.; Zwarenstein M.; Benchimol E.I.; Boutron I.; Campbell M.K.; Erlinge D.; Jawad S.; Ravaud P.; Rice D.B.; Sauve M.; Van Staa T.P.; Thabane L.; Uher R.; Verkooijen H.M.; Juszczak E.; Thombs B.D.. BMJ Open. 2018.

Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data.

Kwakkenbos L; Juszczak E; Hemkens LG; Sampson M; Fröbert O; Relton C; Gale C; Zwarenstein M; Langan SM; Moher D; Boutron I; Ravaud P; Campbell MK; Mc Cord KA; van Staa TP; Thabane L; Uher R; Verkooijen HM; Benchimol EI; Erlinge D; Sauvé M; Torgerson D; Thombs BD. Research integrity and peer review. 2018.

Retrospective assessment of resource use and costs in two investigator-initiated randomized trials exemplified a comprehensive cost item list

Speich B.; von Niederhausern B.; Keiser J.; Furst T.; Kasenda B.; Christ-Crain M.; Hemkens L.G.; Pauli-Magnus C.; Schwenkglenks M.; Briel M.. Journal of clinical epidemiology. 2018.

Routinely collected data for randomized trials: promises, barriers, and implications.

Mc Cord KA; Al-Shahi Salman R; Treweek S; Gardner H; Strech D; Whiteley W; Ioannidis JPA; Hemkens LG. Trials. 2018.

Systematic review and simulation study of ignoring clustered data in surgical trials

Dell-Kuster S.; Droeser R.A.; Schafer J.; Gloy V.; Ewald H.; Schandelmaier S.; Hemkens L.G.; Bucher H.C.; Young J.; Rosenthal R.. The British journal of surgery. 2018.

Systematic review on costs and resource use of randomized clinical trials shows a lack of transparent and comprehensive data

Speich B.; von Niederhausern B.; Schur N.; Hemkens L.G.; Furst T.; Bhatnagar N.; Alturki R.; Agarwal A.; Kasenda B.; Pauli-Magnus C.; Schwenkglenks M.; Briel M.. Journal of clinical epidemiology. 2018.

The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs.

Ladanie A; Speich B; Naudet F; Agarwal A; Pereira TV; Sclafani F; Martin-Liberal J; Schmid T; Ewald H; Ioannidis JPA; Bucher HC; Kasenda B; Hemkens LG. Trials. 2018.

The reporting of studies conducted using observational routinely collected health data statement for pharmacoepidemiology (RECORD-PE).

Langan SM; Schmidt SA; Wing K; Ehrenstein V; Nicholls SG; Filion KB; Klungel O; Petersen I; Sorensen HT; Dixon WG; Guttmann A; Harron K; Hemkens LG; Moher D; Schneeweiss S; Smeeth L; Sturkenboom M; von Elm E; Wang SV; Benchimol EI. BMJ (Clinical research ed.). 2018.

Treatments for subacute cough in primary care: systematic review and meta-analyses of randomised clinical trials.

Speich B; Thomer A; Aghlmandi S; Ewald H; Zeller A; Hemkens LG. The British journal of general practice : the journal of the Royal College of General Practitioners. 2018.

Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: systematic review and meta-analysis.

Ewald H; Santini-Oliveira M; Bühler JE; Vuichard D; Schandelmaier S; Stöckle M; Briel M; Bucher HC; Hemkens LG. HIV clinical trials. 2017.

Niacin for primary and secondary prevention of cardiovascular events

Schandelmaier S.; Briel M.; Saccilotto R.; Olu K.K.; Arpagaus A.; Hemkens L.G.; Nordmann A.J.. Cochrane Database of Systematic Reviews. 2017.

Personalized prescription feedback using routinely collected data to reduce antibiotic use in primary care a randomized clinical trial

Hemkens L.G.; Saccilotto R.; Reyes S.L.; Glinz D.; Zumbrunn T.; Grolimund O.; Gloy V.; Raatz H.; Widmer A.; Zeller A.; Bucher H.C.. JAMA internal medicine. 2017.

Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study.

Schandelmaier S; Tomonaga Y; Bassler D; Meerpohl JJ; von Elm E; You JJ; Bluemle A; Lamontagne F; Saccilotto R; Amstutz A; Bengough T; Stegert M; Olu KK; Tikkinen KAO; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Sun X; Busse JW; Ferreira-González I; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Guyatt G; Bucher HC; Kasenda B; Briel M. The Journal of pediatrics. 2017.

Quality of antibiotic prescribing of Swiss primary care physicians with high prescription rates: a nationwide survey.

Glinz D; Leon Reyes S; Saccilotto R; Widmer AF; Zeller A; Bucher HC; Hemkens LG. The Journal of antimicrobial chemotherapy. 2017.

Towards the development of a comprehensive framework: Qualitative systematic survey of definitions of clinical research quality.

von Niederhäusern B; Schandelmaier S; Mi Bonde M; Brunner N; Hemkens LG; Rutquist M; Bhatnagar N; Guyatt GH; Pauli-Magnus C; Briel M. PLoS One. 2017.

[The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement].

Benchimol EI; Smeeth L; Guttmann A; Harron K; Hemkens LG; Moher D; Petersen I; Sørensen HT; von Elm E; Langan SM; RECORD Working Committee.. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 2016.

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey.

Hemkens LG; Contopoulos-Ioannidis DG; Ioannidis JP. BMJ (Clinical research ed.). 2016.

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey - The authors respond 1

Hemkens,Lars G.; Contopoulos-Ioannidis,Despina G.; Ioannidis,John P.A.. . 2016.

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey - The authors respond 2

Hemkens,Lars G.; Contopoulos-Ioannidis,Despina G.; Ioannidis,John P.A.. . 2016.

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey - The authors respond 3

Hemkens,Lars G.; Contopoulos-Ioannidis,Despina G.; Ioannidis,John P.A.. . 2016.

Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

Kasenda B; von Elm E; You JJ; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Ebrahim S; Schandelmaier S; Sun X; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M. PLoS medicine. 2016.

Authors' reply to Pérol and colleagues.

Hemkens,Lars G; Contopoulos-Ioannidis,Despina G; Ioannidis,John P A. BRIT MED J (PRINT-AUSGABE). 2016.

Better research reporting to improve the utility of routine data for making better treatment decisions.

Hemkens LG; Langan SM; Benchimol EI. Journal of Comparative Effectiveness Research. 2016.

Cardiovascular effects and safety of long-term colchicine treatment: Cochrane review and meta-analysis.

Hemkens LG; Ewald H; Gloy VL; Arpagaus A; Olu KK; Nidorf M; Glinz D; Nordmann AJ; Briel M. Heart (British Cardiac Society). 2016.

Colchicine and Prevention of Cardiovascular Events.

Hemkens LG; Ewald H; Briel M. JAMA. 2016.

Colchicine for prevention of cardiovascular events.

Hemkens LG; Ewald H; Gloy VL; Arpagaus A; Olu KK; Nidorf M; Glinz D; Nordmann AJ; Briel M. The Cochrane database of systematic reviews. 2016.

Current use of routinely collected health data to complement randomized controlled trials: a meta-epidemiological survey.

Hemkens LG; Contopoulos-Ioannidis DG; Ioannidis JP. CMAJ open. 2016.

Personalized prescription feedback to reduce antibiotic overuse in primary care: rationale and design of a nationwide pragmatic randomized trial.

Hemkens LG; Saccilotto R; Reyes SL; Glinz D; Zumbrunn T; Grolimund O; Gloy V; Raatz H; Widmer A; Zeller A; Bucher HC. BMC INFECTIOUS DISEASES. 2016.

Planning and reporting of quality-of-life outcomes in cancer trials.

Schandelmaier S; Conen K; von Elm E; You JJ; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Sun X; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M; Kasenda B; DISCO study group.. Annals of Oncology. 2016.

Premature discontinuation of prospective clinical studies approved by a research ethics committee - A comparison of randomised and non-randomised studies

Blumle A.; Schandelmaier S.; Oeller P.; Kasenda B.; Briel M.; von Elm E.; Akl E.A.; Amstutz A.; Bassler D.; Bengough T.; Bucher H.C.; Burnand B.; Busse J.W.; Carrasco-Labra A.; Ebrahim S.; Faulhaber M.; Gloy V.; Ferreira-Gonzalez I.; Guyatt G.H.; Hemkens L.G.; Johnston B.C.; Lamontagne F.; Meerpohl J.J.; Mertz D.; Moja L.; Mulla S.; Neumann I.; Nordmann A.; Olu K.K.; Raatz H.; Rosenthal R.; Saccilotto R.; Schwenkglenks M.; Stegert M.; Sun X.; Tikkinen K.A.O.; Tomonaga Y.; Walter M.A.; Vandvik P.O.; You J.J.. PLoS One. 2016.

Premature discontinuation of randomized trials in critical and emergency care: A retrospective cohort study

Schandelmaier S.; Von Elm E.; You J.J.; Blumle A.; Tomonaga Y.; Lamontagne F.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.J.; Stegert M.; Olu K.K.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.M.; Mertz D.; Akl E.A.; Sun X.; Bassler D.; Busse J.W.; Ferreira-Gonzalez I.; Nordmann A.; Gloy V.; Raatz H.; Moja L.; Rosenthal R.; Ebrahim S.; Vandvik P.O.; Johnston B.C.; Walter M.A.; Burnand B.; Schwenkglenks M.; Hemkens L.G.; Cook D.J.; Meade M.O.; Bucher H.C.; Kasenda B.; Briel M.. Critical care medicine. 2016.

Routinely collected data and comparative effectiveness evidence: Promises and limitations

Hemkens L.G.; Contopoulos-Ioannidis D.G.; Ioannidis J.P.A.. CMAJ. 2016.

Routinely collected data may usefully supplement randomised controlled data on treatment effects for mortality Reply

Hemkens, Lars G.; Contopoulos-Ioannidis, Despina G.; Ioannidis, John P. A.. BMJ (Clinical research ed.). 2016.

The reporting of studies using routinely collected health data was often insufficient.

Hemkens LG; Benchimol EI; Langan SM; Briel M; Kasenda B; Januel JM; Herrett E; von Elm E. Journal of clinical epidemiology. 2016.

Association between ambient air pollution and diabetes mellitus in Europe and North America: Systematic review and meta-analysis

Eze I.C.; Hemkens L.G.; Bucher H.C.; Hoffmann B.; Schindler C.; Kunzli N.; Schikowski T.; Probst-Hensch N.M.. Environmental health perspectives. 2015.

Comparative effectiveness of tenofovir in treatment-naïve HIV-infected patients: systematic review and meta-analysis.

Hemkens, Lars G; Ewald, Hannah; Santini-Oliveira, Marilia; Bühler, Julian-Emanuel; Vuichard, Danielle; Schandelmaier, Stefan; Stöckle, Marcel; Briel, Matthias; Bucher, Heiner C. HIV clinical trials. 2015.

Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.

Rosenthal R; Kasenda B; Dell-Kuster S; von Elm E; You J; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla S; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Olu KK; Raatz H; Moja L; Ebrahim S; Schandelmaier S; Sun X; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M. Annals of Surgery. 2015.

Planning and reporting of quality-of-life outcomes in cancer trials.

Schandelmaier S; Conen K; von Elm E; You JJ; Blümle A; Tomonaga Y; Amstutz A; Briel M; Kasenda B; DISCO study group.. Annals of Oncology. 2015.

The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement.

Benchimol EI; Smeeth L; Guttmann A; Harron K; Moher D; Petersen I; Sørensen HT; von Elm E; Langan SM; RECORD Working Committee.. PLoS medicine. 2015.

Clinical effectiveness of stress-reduction techniques in patients with hypertension: Systematic reviewand meta-analysis

Nagele E.; Jeitler K.; Horvath K.; Semlitsch T.; Posch N.; Herrmann K.H.; Grouven U.; Hermanns T.; Hemkens L.G.; Siebenhofer A.. Journal of Hypertension. 2014.

Colchicine for prevention of cardiovascular events

Hemkens L.G.; Gloy V.L.; Olu K.K.; Nordmann A.J.; Briel M.. Cochrane Database of Systematic Reviews. 2014.

HIV infection and cardiovascular disease.

Hemkens LG; Bucher HC. European heart journal. 2014.

Prevalence, characteristics, and publication of discontinued randomized trials

Kasenda B.; Von Elm E.; You J.; Blumle A.; Tomonaga Y.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.J.; Stegert M.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.M.; Mertz D.; Akl E.A.; Bassler D.; Busse J.W.; Ferreira-Gonzalez I.; Lamontagne F.; Nordmann A.; Gloy V.; Raatz H.; Moja L.; Rosenthal R.; Ebrahim S.; Schandelmaier S.; Xin S.; Vandvik P.O.; Johnston B.C.; Walter M.A.; Burnand B.; Schwenkglenks M.; Hemkens L.G.; Bucher H.C.; Guyatt G.H.; Briel M.. JAMA. 2014.

Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.

Kasenda B; Schandelmaier S; Sun X; von Elm E; You J; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M; DISCO Study Group.. BMJ (Clinical research ed.). 2014.

Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications (vol 349, g4539, 2014)

Kasenda, Benjamin; Schandelmaier, Stefan; Sun, Xin; von Elm, Erik; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramon; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco-Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira-Gonzalez, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias. BMJ (Clinical research ed.). 2014.

All Nations Depend on the Global Knowledge Pool - Analysis of Country of Origin of Studies Used for Health Technology Assessments in Germany

Herrmann K.H.; Wolff R.; Scheibler F.; Waffenschmidt S.; Hemkens L.G.; Sauerland S.; Antes G.. PLoS One. 2013.

Concordance of effects of medical interventions on hospital admission and readmission rates with effects on mortality

Hemkens L.G.; Contopoulos-Ioannidis D.G.; Ioannidis J.P.A.. CMAJ. 2013.

Increasing physical activity for the treatment of hypertension: A systematic review and meta-analysis

Semlitsch T.; Jeitler K.; Hemkens L.G.; Horvath K.; Nagele E.; Schuermann C.; Pignitter N.; Herrmann K.H.; Waffenschmidt S.; Siebenhofer A.. Sports Medicine. 2013.

Pilotprojekt zur Verbesserung der Qualität der Antibiotikaverschreibung in der ambulanten Versorgung in der Schweiz.

Hemkens,LG; Saccilotto,R; Zumbrunn,T; Widmer,A; Bucher,HC; Zeller,A. . 2013.

CLINICAL EFFECTIVENESS OF INCREASED PHYSICAL ACTIVITY IN TYPE 2 DIABETES, SYSTEMATIC REVIEW

Herrmann, K. H.; Semlitsch, T.; Jeitler, K.; Schuermann, C.; Janzen, T.; Hemkens, L. G.; Matyas, E.; Pignitter, N.; Siebenhofer-kroitzsch, A.; Horvath, K.. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2012.

Self-management of oral anticoagulation in elderly patients - effects on treatment-related quality of life.

Siebenhofer A; Hemkens LG; Rakovac I; Spat S; Didjurgeit U; SPOG 60+ Study Group.. Thrombosis research. 2012.

Benefit assessment of salt reduction in patients with hypertension: Systematic overview

Matyas E.; Jeitler K.; Horvath K.; Semlitsch T.; Hemkens L.G.; Pignitter N.; Siebenhofer A.. Journal of Hypertension. 2011.

Long-term effects of weight-reducing diets in hypertensive patients.

Siebenhofer A.; Jeitler K.; Berghold A.; Waltering A.; Hemkens L.G.; Semlitsch T.; Pachler C.; Strametz R.; Horvath K.. Cochrane Database of Systematic Reviews. 2011.

Long-term effects of weight-reducing diets in hypertensive patients.

Siebenhofer A; Jeitler K; Berghold A; Waltering A; Hemkens LG; Semlitsch T; Pachler C; Strametz R; Horvath K. Cochrane Database of Systematic Reviews. 2011.

Low-dose rate brachytherapy for men with localized prostate cancer.

Peinemann F.; Grouven U.; Hemkens L.G.; Bartel C.; Borchers H.; Pinkawa M.; Heidenreich A.; Sauerland S.. Cochrane Database of Systematic Reviews. 2011.

Low-dose rate brachytherapy for men with localized prostate cancer.

Peinemann F; Grouven U; Hemkens LG; Bartel C; Borchers H; Pinkawa M; Heidenreich A; Sauerland S. Cochrane Database of Systematic Reviews. 2011.

Insufficient evaluation of adverse events is not a proof of safety.

Hemkens LG; Grouven U; Bender R; Sawicki PT. Diabetologia. 2010.

Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues. Reply to Nagel JM, Mansmann U, Wegscheider K et al. [letter] and Simon D [letter]

Grouven U.; Hemkens L.G.; Bender R.; Sawicki P.T.. Diabetologia. 2010.

Insulin glargine and cancer

Hemkens L.G.; Bender R.; Grouven U.; Sawicki P.T.. Lancet (London, England). 2009.

Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: A cohort study

Hemkens L.G.; Grouven U.; Bender R.; Gunster C.; Gutschmidt S.; Selke G.W.; Sawicki P.T.. Diabetologia. 2009.

A randomized trial comparing INR monitoring devices in patients with anticoagulation self-management: evaluation of a novel error-grid approach.

Hemkens LG; Hilden KM; Hartschen S; Kaiser T; Didjurgeit U; Hansen R; Bender R; Sawicki PT. Journal of thrombosis and thrombolysis. 2008.

Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial: response to Blume et al.

Hemkens LG; Waltering A. Diabetes care. 2008.

Akutes Herzinfarktrisiko bei mangelnder Clopidogrelgabe nach koronarer Stentimplantation: Dauer der Clopidogrelgabe unklar.

Waltering,A; Hemkens,L; Didjurgeit,U. . 2007.

Does primary prevention with acetylsalicylic acid lower the mortality from cardiovascular diseases and tumors in women?

. Deutsche medizinische Wochenschrift (1946). 2007.

Statine: Regeln evidenzbasierter Medizin.

Hemkens,L; Waltering,A. . 2005.