Departement
Klinische Forschung
Achtung: Diese Seite kann nur von Administratoren besucht werden, da Sie nicht freigeschalten wurde.
Zurück
Publications Briel Matthias

Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group.

EU-Response investigators group.; Diallo A; Trøseid M; Simensen VC; Boston A; Demotes J; Olsen IC; Chung F; Paiva JA; Hites M; Ader F; Arribas JR; Baratt-Due A; Melien Ø; Tacconelli E; Staub T; Greil R; Tsiodras S; Briel M; Esperou H; Mentré F; Eustace J; Saillard J; Delmas C; LeMestre S; Dumousseaux M; Costagliola D; Røttingen JA; Yazdanpanah Y. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2022.

A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study.

Speich B; Odutayo A; Peckham N; Ooms A; Stokes JR; Saccilotto R; Gryaznov D; von Niederhäusern B; Copsey B; Altman DG; Briel M; Hopewell S. Trials. 2022.

A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols.

Schönenberger CM; Griessbach A; Taji Heravi A; Gryaznov D; Gloy VL; Lohner S; Klatte K; Ghosh N; Lee H; Mansouri A; Marian IR; Saccilotto R; Nury E; Busse JW; von Niederhäusern B; Mertz D; Blümle A; Odutayo A; Hopewell S; Speich B; Briel M. Journal of clinical epidemiology. 2022.

Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial.

Speich B; Chammartin F; Abela IA; Amico P; Stoeckle MP; Eichenberger AL; Hasse B; Braun DL; Schuurmans MM; Müller TF; Tamm M; Audigé A; Mueller NJ; Rauch A; Günthard HF; Koller MT; Trkola A; Briel M; Kusejko K; Bucher HC; Swiss HIV Cohort Study and the Swiss Transplant Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022.

A systematic review of meta-research studies finds substantial methodological heterogeneity in citation analyses to monitor evidence-based research.

Nørgaard B; Briel M; Chrysostomou S; Ristic Medic D; Buttigieg SC; Kiisk E; Puljak L; Bala M; Pericic TP; Lesniak W; Zając J; Lund H; Pieper D. Journal of clinical epidemiology. 2022.

A systematic survey of methods guidance suggests areas for improvement regarding access, development, and transparency.

Hirt J; Ewald H; Lawson DO; Hemkens LG; Briel M; Schandelmaier S. Journal of clinical epidemiology. 2022.

Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV.

Chammartin F; Kusejko K; Pasin C; Trkola A; Briel M; Amico P; Stoekle MP; Eichenberger AL; Hasse B; Braun DL; Schuurmans MM; Müller TF; Tamm M; Mueller NJ; Rauch A; Koller MT; Günthard HF; Bucher HC; Speich B; Abela IA; Swiss HIV Cohort Study. AIDS (London, England). 2022.

Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients

Kusejko K.; Chammartin F.; Smith D.; Odermatt M.; Schuhmacher J.; Koller M.; Gunthard H.F.; Briel M.; Bucher H.C.; Speich B.; Abela I.; Aebi-Popp K.; Anagnostopoulos A.; Battegay M.; Bernasconi E.; Braun D.L.; Bucher H.C.; Calmy A.; Cavassini M.; Ciuffi A.; Dollenmaier G.; Egger M.; Elzi L.; Fehr J.; Fellay J.; Furrer H.; Fux C.A.; Gunthard H.F.; Hachfeld A.; Haerry D.; Hasse B.; Hirsch H.H.; Hoffmann M.; Hosli I.; Huber M.; Kahlert C.R.; Kaiser L.; Keiser O.; Klimkait T.; Kouyos R.D.; Kovari H.; Kusejko K.; Martinetti G.; Martinez de Tejada B.; Marzolini C.; Metzner K.J.; Muller N.; Nemeth J.; Nicca D.; Paioni P.; Pantaleo G.; Perreau M.; Rauch A.; Schmid P.; Speck R.; Stockle M.; Tarr P.; Trkola A.; Wandeler G.; Yerly S.; Amico P.; Aubert J.-D.; Banz V.; Beckmann S.; Beldi G.; Berger C.; Berishvili E.; Berzigotti A.; Binet I.; Bochud P.-Y.; Branca S.; Bucher H.; Catana E.; Cairoli A.; Chalandon Y.; De Geest S.; De Rougemont O.; De Seigneux S.; Dickenmann M.; Dreifuss J.L.; Duchosal M.; Fehr T.; Ferrari-Lacraz S.; Garzoni C.; Golshayan D.; Goossens N.; Halter F.H.J.; Heim D.; Hess C.; Hillinger S.; Hirsch H.H.; Hirt P.; Hofbauer G.; Huynh-Do U.; Immer F.; Laager M.; Laesser B.; Lamoth F.; Lehmann R.; Leichtle A.; Manuel O.; Marti H.-P.; Martinelli M.; McLin V.; Mellac K.; Mercay A.; Mettler K.; Muller A.; Mueller N.J.; Muller-Arndt U.; Mullhaupt B.; Nageli M.; Oldani G.; Pascual M.; Passweg J.; Pazeller R.; Posfay-Barbe K.; Rick J.; Rosselet A.; Rossi S.; Rothlin S.; Ruschitzka F.; Schachtner T.; Schanz U.; Schaub S.; Scherrer A.; Schnyder A.; Schuurmans M.; Schwab S.; Sengstag T.; Simonetta F.; Stampf S.; Steiger J.; Stirnimann G.; Sturzinger U.; Van Delden C.; Venetz J.-P.; Villard J.; Vionnet J.; Wick M.; Wilhelm M.; Yerly P.. BMC INFECTIOUS DISEASES. 2022.

Investigational medicinal products, related costs and hospital pharmacy services for investigator-initiated trials: A mixed-methods study

Heravi A.T.; Henn A.; Deuster S.; McLennan S.; Gloy V.; Mitter V.R.; Briel M.. PLoS One. 2022.

Investigators' sense of failure thwarted transparency in clinical trials discontinued for poor recruitment.

Satalkar P; McLennan S; Elger BS; von Elm E; Matthias B. Journal of clinical epidemiology. 2022.

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.

Speich B; Gryaznov D; Busse JW; Gloy VL; Lohner S; Klatte K; Taji Heravi A; Ghosh N; Lee H; Mansouri A; Marian IR; Saccilotto R; Nury E; Kasenda B; Ojeda-Ruiz E; Schandelmaier S; Tomonaga Y; Amstutz A; Pauli-Magnus C; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Wong J; Chow N; Hong PJ; Mc Cord-De Iaco K; Sricharoenchai S; Agarwal A; Schwenkglenks M; Hemkens LG; von Elm E; Copsey B; Griessbach AN; Schönenberger C; Mertz D; Blümle A; von Niederhäusern B; Hopewell S; Odutayo A; Briel M. PLoS medicine. 2022.

Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit Recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE).

Gryaznov D; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Blümle A; Schandelmaier S; Mertz D; Odutayo A; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Lohner S; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Taji Heravi A; Wong J; Chow N; Hong P; McCord-De Iaco KA; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens L; Hopewell S; Von Elm E; Briel M. BMJ Open. 2022.

Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility.

Gloy V; Speich B; Griessbach A; Taji Heravi A; Schulz A; Fabbro T; Magnus CP; McLennan S; Bertram W; Briel M. BMC Medical Research Methodology. 2022.

A contextual analysis and logic model for integrated care for frail older adults living at home: The inspire project

Yip O.; Huber E.; Stenz S.; Zullig L.L.; Zeller A.; De Geest S.M.; Deschodt M.; Briel M.; Schwenkglenks M.; Zuniga F.; Vounatsou P.; Quinto C.; Blozik E.; Siqeca F.; Jara M.J.M.. International Journal of Integrated Care. 2021.

A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials.

Speich B; Logullo P; Deuster S; Marian IR; Moschandreas J; Taji Heravi A; Gloy V; Briel M; Hopewell S; MAking Randomized Trials Affordable (MARTA) Group.. Journal of clinical epidemiology. 2021.

Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs.

Herbrand AK; Schmitt AM; Briel M; Ewald H; Goldkuhle M; Diem S; Hoogkamer A; Joerger M; Moffa G; Novak U; Hemkens LG; Kasenda B. JAMA Network Open. 2021.

A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®.

Speich B; Chammartin F; Smith D; Stoeckle MP; Amico P; Eichenberger AL; Hasse B; Schuurmans MM; Müller T; Tamm M; Dickenmann M; Abela IA; Trkola A; Hirsch HH; Manuel O; Cavassini M; Hemkens LG; Briel M; Mueller NJ; Rauch A; Günthard HF; Koller MT; Bucher HC; Kusejko K; study groups from the Swiss HIV Cohort Study and the Swiss Transplant Cohort Study.. Trials. 2021.

Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials.

McLennan S; Nussbaumer-Streit B; Hemkens LG; Briel M. JAMA Network Open. 2021.

Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: A patient-level meta-analysis from randomized controlled trials

Heilmann E.; Gregoriano C.; Annane D.; Reinhart K.; Bouadma L.; Wolff M.; Chastre J.; Luyt C.-E.; Tubach F.; Branche A.R.; Briel M.; Christ-Crain M.; Welte T.; Corti C.; De Jong E.; Nijsten M.; De Lange D.W.; Van Oers J.A.H.; Beishuizen A.; Girbes A.R.J.; Deliberato R.O.; Schroeder S.; Kristoffersen K.B.; Layios N.; Damas P.; Lima S.S.S.; Nobre V.; Wei L.; Oliveira C.F.; Shehabi Y.; Stolz D.; Tamm M.; Verduri A.; Wang J.-X.; Drevet S.; Gavazzi G.; Mueller B.; Schuetz P.. Age and Ageing. 2021.

Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials.

Taji Heravi A; Gryaznov D; Schandelmaier S; Kasenda B; Briel M; Adherence to SPIRIT Recommendations (ASPIRE) Study Group.. JAMA Network Open. 2021.

Exploring reasons for recruitment failure in clinical trials: a qualitative study with clinical trial stakeholders in Switzerland, Germany, and Canada.

Briel M; Elger BS; McLennan S; Schandelmaier S; von Elm E; Satalkar P. Trials. 2021.

Higher PEEP for acute respiratory distress syndrome: A Bayesian meta-analysis of randomised clinical trials

Neto A.S.; Tomlinson G.; Sahetya S.K.; Ball L.; Nichol A.D.; Hodgson C.; Cavalcanti A.B.; Briel M.; de Abreu M.G.; Pelosi P.; Schultz M.J.; Goligher E.C.. Critical Care and Resuscitation. 2021.

Influence of Prednisone on Inflammatory Biomarkers in Community-Acquired Pneumonia: Secondary Analysis of a Randomized Trial

Raess N.; Schuetz P.; Cesana-Nigro N.; Winzeler B.; Urwyler S.A.; Schaedelin S.; Rodondi N.; Blum M.R.; Briel M.; Mueller B.; Christ-Crain M.; Blum C.A.. Journal of Clinical Pharmacology. 2021.

Monitoring strategies for clinical intervention studies.

Klatte K; Pauli-Magnus C; Love SB; Sydes MR; Benkert P; Bruni N; Ewald H; Arnaiz Jimenez P; Bonde MM; Briel M. The Cochrane database of systematic reviews. 2021.

Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management

McLennan S.; Griessbach A.; Briel M.. JAMA Network Open. 2021.

Reliability of Trial Information Across Registries for Trials With Multiple Registrations: A Systematic Review.

Speich B; Gloy VL; Klatte K; Gryaznov D; Taji Heravi A; Ghosh N; Marian IR; Lee H; Mansouri A; Lohner S; Saccilotto R; Nury E; Chan AW; Blümle A; Odutayo A; Hopewell S; Briel M; Adherence to Spirit Recommendations (ASPIRE) Study Group.. JAMA Network Open. 2021.

Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study.

Lohner S; Gryaznov D; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Schandelmaier S; Mertz D; Odutayo A; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Bischoff K; Wollmann K; Rehner L; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Heravi AT; Wong J; Chow N; Hong PJ; McCord K; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens LG; Hopewell S; von Elm E; Blümle A; Briel M. Journal of clinical epidemiology. 2021.

Surgery for obstructive sleep apnoea in adults

Berg B.-I.; Werz S.M.; Pfeifle M.; Schrader F.; Jurgens P.; Briel M.. Cochrane Database of Systematic Reviews. 2021.

The INSPIRE Population Survey: development, dissemination and respondent characteristics.

Siqeca F; Obas K; Yip O; Stenz S; Vounatsou P; Briel M; Schwenkglenks M; Quinto C; Blozik E; Zeller A; Zullig LL; De Geest S; Deschodt M. BMC Medical Research Methodology. 2021.

Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis

Walter M.A.; Nesti C.; Spanjol M.; Kollar A.; Butikofer L.; Gloy V.L.; Dumont R.A.; Seiler C.A.; Christ E.R.; Radojewski P.; Briel M.; Kaderli R.M.. Cochrane Database of Systematic Reviews. 2021.

A scoping review shows that several nonvalidated budget planning tools for randomized trials are available.

Speich B; Gloy V; Schur N; Ewald H; Hemkens LG; Schwenkglenks M; Briel M; MAking Randomized Trials Affordable (MARTA) Group.. Journal of clinical epidemiology. 2020.

A systematic survey of randomised trials that stopped early for reasons of futility.

Walter SD; Han H; Guyatt GH; Bassler D; Bhatnagar N; Gloy V; Schandelmaier S; Briel M. BMC Medical Research Methodology. 2020.

Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey.

Schandelmaier S; Schmitt AM; Herbrand AK; Glinz D; Ewald H; Briel M; Guyatt GH; Hemkens LG; Kasenda B. BMJ Open. 2020.

Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016.

Ladanie A; Schmitt AM; Speich B; Naudet F; Agarwal A; Pereira TV; Sclafani F; Herbrand AK; Briel M; Martin-Liberal J; Schmid T; Ewald H; Ioannidis JPA; Bucher HC; Kasenda B; Hemkens LG. JAMA Network Open. 2020.

Core components and impact of nurse-led integrated care models for home-dwelling older people: A systematic review and meta-analysis.

Deschodt M; Laurent G; Cornelissen L; Yip O; Zúñiga F; Denhaerynck K; Briel M; Karabegovic A; De Geest S; INSPIRE consortium.. International journal of nursing studies. 2020.

COVID-19 randomised trial protocols: rapid publication without barriers.

Treweek S; Jüni P; Li T; Collin J; Briel M; Chan AW; Hemming K; Meurer WJ; Sydes MR; Grimshaw JM. . 2020.

Design, analysis and reporting of multi-arm trials and strategies to address multiple testing.

Odutayo A; Gryaznov D; Copsey B; Monk P; Speich B; Roberts C; Vadher K; Dutton P; Briel M; Hopewell S; Altman DG; ASPIRE study group.. International journal of epidemiology. 2020.

Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses.

Schandelmaier S; Briel M; Varadhan R; Schmid CH; Devasenapathy N; Hayward RA; Gagnier J; Borenstein M; van der Heijden GJMG; Dahabreh IJ; Sun X; Sauerbrei W; Walsh M; Ioannidis JPA; Thabane L; Guyatt GH. CMAJ. 2020.

Digital tools for trial recruitment and retention-plenty of tools but rigorous evaluation is in short supply.

Treweek S; Briel M. . 2020.

Erratum to "A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses" [J Clin Epidemiol. 2019;113:159-67].

Schandelmaier S; Chang Y; Bala MM; Devasenapathy N; Devji T; Kwong JSW; Colunga Lozano LE; Lee Y; Agarwal A; Bhatnagar N; Ewald H; Zhang Y; Sun X; Thabane L; Walsh M; Briel M; Guyatt GH. . 2020.

Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis.

Schünemann HJ; Ventresca M; Crowther M; Briel M; Zhou Q; Noble S; Macbeth F; Griffiths G; Garcia D; Lyman GH; Di Nisio M; Iorio A; Mbuagbaw L; Neumann I; van Es N; Brouwers M; Guyatt G; Streiff MB; Marcucci M; Baldeh T; Florez ID; Alma OG; Solh Z; Bossuyt PM; Kahale LA; Ageno W; Bozas G; Büller HR; Lebeau B; Lecumberri R; Loprinzi C; McBane R; Sideras K; Maraveyas A; Pelzer U; Perry J; Klerk C; Agnelli G; Akl EA. Lancet Haematology. 2020.

Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial.

Speich B; Schroter S; Briel M; Moher D; Puebla I; Clark A; Maia Schlüssel M; Ravaud P; Boutron I; Hopewell S. BMJ Open. 2020.

Individual participant data meta-analysis of 14 randomized trials evaluating prophylactic heparin in ambulatory cancer patients

Schünemann HJ; Ventresca M; Crowther M; Briel M; Zhou Q; Noble S; Macbeth F; Griffiths G, Garcia D; Lyman G; DiNisio M; Iorio A; Beyene J; Mbuagbaw L; Neumann I; Van Es N; Brouwers M; Brozek J; Guyatt G; Moll S; Santesso N; Streiff M; Marcucci M; Baldeh T; Florez I; Alma OG; Solh Z; Ozkan M; Altinbas M; Ageno W; Bleker S; Bozas G; Büller HR; Evans J; Lebeau B; Lecumberri R; Loprinzi C; McBane R; Sideras K; Zulian G; Maraveyas A; Pelzer U; Perry J; Akl EA; and the IPDMA heparin use in cancer patients research group. . 2020.

Introduction to statistical simulations in health research

Boulesteix A.-L.; Groenwold R.H.H.; Abrahamowicz M.; Binder H.; Briel M.; Hornung R.; Morris T.P.; Rahnenfuhrer J.; Sauerbrei W.. BMJ Open. 2020.

Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide.

Ventresca M; Schünemann HJ; Macbeth F; Clarke M; Thabane L; Griffiths G; Noble S; Garcia D; Marcucci M; Iorio A; Zhou Q; Crowther M; Akl EA; Lyman GH; Gloy V; DiNisio M; Briel M. BMC Medical Research Methodology. 2020.

Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)-rationale and design for an international collaborative study.

Kasenda B; Liu J; Jiang Y; Gajewski B; Wu C; von Elm E; Schandelmaier S; Moffa G; Trelle S; Schmitt AM; Herbrand AK; Gloy V; Speich B; Hopewell S; Hemkens LG; Sluka C; McGill K; Meade M; Cook D; Lamontagne F; Tréluyer JM; Haidich AB; Ioannidis JPA; Treweek S; Briel M. Trials. 2020.

Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects.

Gryaznov D; Odutayo A; von Niederhäusern B; Speich B; Kasenda B; Ojeda-Ruiz E; Blümle A; Schandelmaier S; Mertz D; Tomonaga Y; Amstutz A; Pauli-Magnus C; Gloy V; Bischoff K; Wollmann K; Rehner L; Lohner S; Meerpohl JJ; Nordmann A; Klatte K; Ghosh N; Heravi AT; Wong J; Chow N; Hong PJ; Cord KM; Sricharoenchai S; Busse JW; Agarwal A; Saccilotto R; Schwenkglenks M; Moffa G; Hemkens LG; Hopewell S; von Elm E; Briel M. Trials. 2020.

Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC).

Lawson DO; Puljak L; Pieper D; Schandelmaier S; Collins GS; Brignardello-Petersen R; Moher D; Tugwell P; Welch VA; Samaan Z; Thombs BD; Nørskov AK; Jakobsen JC; Allison DB; Mayo-Wilson E; Young T; Chan AW; Briel M; Guyatt GH; Thabane L; Mbuagbaw L. BMJ Open. 2020.

The fragility of trial results involves more than statistical significance alone.

Walter SD; Thabane L; Briel M. Journal of clinical epidemiology. 2020.

The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta-analysis.

van Es N; Ventresca M; Di Nisio M; Zhou Q; Noble S; Crowther M; Briel M; Garcia D; Lyman GH; Macbeth F; Griffiths G; Iorio A; Mbuagbaw L; Neumann I; Brozek J; Guyatt G; Streiff MB; Baldeh T; Florez ID; Gurunlu Alma O; Agnelli G; Ageno W; Marcucci M; Bozas G; Zulian G; Maraveyas A; Lebeau B; Lecumberri R; Sideras K; Loprinzi C; McBane R; Pelzer U; Riess H; Solh Z; Perry J; Kahale LA; Bossuyt PM; Klerk C; Büller HR; Akl EA; Schünemann HJ; IPDMA Heparin Use in Cancer Patients Research Group.. Journal of thrombosis and haemostasis : JTH. 2020.

Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis

Walter M.A.; Spanjol M.; Kollar A.; Butikofer L.; Gloy V.L.; Dumont R.A.; Seiler C.A.; Christ E.R.; Radojewski P.; Briel M.; Kaderli R.M.. Cochrane Database of Systematic Reviews. 2020.

Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed.

Treweek S; Bevan S; Bower P; Briel M; Campbell M; Christie J; Collett C; Cotton S; Devane D; El Feky A; Galvin S; Gardner H; Gillies K; Hood K; Jansen J; Littleford R; Parker A; Ramsay C; Restrup L; Sullivan F; Torgerson D; Tremain L; von Elm E; Westmore M; Williams H; Williamson PR; Clarke M. Trials. 2020.

Uncertainties about the need for ethics approval in Switzerland: a mixed-methods study.

Gloy V; McLennan S; Rinderknecht M; Ley B; Meier B; Driessen S; Gervasoni P; Hirschel B; Benkert P; Gilles I; von Elm E; Briel M. Swiss Medical Weekly. 2020.

Working Through Ethics Review of Big Data Research Projects: An Investigation into the Experiences of Swiss and American Researchers

Favaretto M.; De Clercq E.; Briel M.; Elger B.S.. Journal of empirical research on human research ethics : JERHRE. 2020.

A guidance was developed to identify participants with missing outcome data in randomized controlled trials.

Kahale LA; Guyatt GH; Agoritsas T; Briel M; Busse JW; Carrasco-Labra A; Khamis AM; Zhang Y; Hooft L; Scholten RJPM; Akl EA. Journal of clinical epidemiology. 2019.

A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses.

Schandelmaier S; Chang Y; Devasenapathy N; Devji T; Kwong JSW; Colunga Lozano LE; Lee Y; Agarwal A; Bhatnagar N; Ewald H; Zhang Y; Sun X; Thabane L; Walsh M; Briel M; Guyatt GH. Journal of clinical epidemiology. 2019.

Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: a matched qualitative study.

Briel M; Speich B; von Elm E; Gloy V. Trials. 2019.

Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project.

Herbrand AK; Schmitt AM; Briel M; Diem S; Ewald H; Hoogkamer A; Joerger M; Mc Cord KA; Novak U; Sricharoenchai S; Hemkens LG; Kasenda B. ESMO open. 2019.

Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial.

Blum CA; Schuetz P; Nigro N; Winzeler B; Arici B; Refardt J; Urwyler SA; Rodondi N; Blum MR; Briel M; Mueller B; Christ-Crain M. Clinical endocrinology. 2019.

Current use and costs of electronic health records for clinical trial research: a descriptive study.

Mc Cord KA; Ewald H; Ladanie A; Briel M; Speich B; Bucher HC; Hemkens LG; RCD for RCTs initiative and the Making Randomized Trials More Affordable Group.. CMAJ open. 2019.

Functional aging in health and heart failure: the COmPLETE Study.

Wagner J; Knaier R; Infanger D; Arbeev K; Briel M; Dieterle T; Hanssen H; Faude O; Roth R; Hinrichs T; Schmidt-Trucksäss A. BMC Cardiovascular Disorders. 2019.

Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis.

Blum S; Meyre P; Aeschbacher S; Berger S; Auberson C; Briel M; Osswald S; Conen D. Heart rhythm. 2019.

Monitoring strategies for clinical intervention studies

Klatte K.; Pauli-Magnus C.; Love S.; Sydes M.; Benkert P.; Bruni N.; Ewald H.; Arnaiz Jimenez P.; Bonde M.M.; Briel M.. Cochrane Database of Systematic Reviews. 2019.

Patient-reported outcomes

Johnston B.C.; Patrick D.L.; Devji T.; Maxwell L.J.; Bingham C.O.; Beaton D.E.; Boers M.; Briel M.; Busse J.W.; Carrasco-Labra A.; Christensen R.; Da Costa B.R.; Dib R.E.; Lyddiatt A.; Ostelo R.W.; Shea B.; Singh J.; Terwee C.B.; Williamson P.R.; Gagnier J.J.; Tugwell P.; Guyatt G.H.. . 2019.

Randomised trials with provision for early stopping for benefit (or harm): The impact on the estimated treatment effect.

Walter SD; Guyatt GH; Bassler D; Briel M; Ramsay T; Han HD. STATISTICS IN MEDICINE. 2019.

Reporting Quality of Journal Abstracts for Surgical Randomized Controlled Trials Before and After the Implementation of the CONSORT Extension for Abstracts.

Speich B; Mc Cord KA; Agarwal A; Gloy V; Gryaznov D; Moffa G; Hopewell S; Briel M. World Journal of Surgery. 2019.

Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation.

Speich B; Schur N; Gryaznov D; von Niederhäusern B; Hemkens LG; Schandelmaier S; Amstutz A; Kasenda B; Pauli-Magnus C; Ojeda-Ruiz E; Tomonaga Y; McCord K; Nordmann A; von Elm E; Briel M; Schwenkglenks M; a collaboration of the MARTA (MAking Randomized Trials Affordable) and ASPIRE (Adherence to Standard Protocol Items: REcommendations for interventional trials) Study Groups.. PLoS One. 2019.

Risk of Hospital Admissions in Patients With Atrial Fibrillation: A Systematic Review and Meta-analysis.

Meyre P; Blum S; Berger S; Aeschbacher S; Schoepfer H; Briel M; Osswald S; Conen D. The Canadian journal of cardiology. 2019.

Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies.

Ladanie A; Speich B; Briel M; Sclafani F; Bucher HC; Agarwal A; Ioannidis JPA; Pereira TV; Kasenda B; Hemkens LG. Journal of clinical epidemiology. 2019.

Therapeutic Options for Neuroendocrine Tumors: A Systematic Review and Network Meta-analysis.

Kaderli RM; Spanjol M; Kollár A; Bütikofer L; Gloy V; Dumont RA; Seiler CA; Christ ER; Radojewski P; Briel M; Walter MA. JAMA oncology. 2019.

The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review.

Kernen P; Steveling-Klein EH; Saccilotto RT; Raatz H; Briel M; Koller MT; Westwood M; Bucher HC; Miedinger D; Leuppi JD. Swiss Medical Weekly. 2019.

Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE).

von Niederhäusern B; Guyatt GH; Briel M; Pauli-Magnus C. PLoS medicine. 2018.

Bariatric surgery among patients with heart failure: a systematic review and meta-analysis.

Berger S; Meyre P; Blum S; Aeschbacher S; Ruegg M; Briel M; Conen D. Open heart. 2018.

Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Metaanalysis.

Briel M; Spoorenberg SMC; Snijders D; Torres A; Fernandez-Serrano S; Meduri GU; Gabarrús A; Blum CA; Confalonieri M; Kasenda B; Siemieniuk RAC; Boersma W; Bos WJW; Christ-Crain M; Ovidius Study Group.; Capisce Study Group.; STEP Study Group.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2018.

Corticosteroid therapy for sepsis: a clinical practice guideline.

Lamontagne F; Rochwerg B; Lytvyn L; Guyatt GH; Møller MH; Annane D; Kho ME; Adhikari NKJ; Machado F; Vandvik PO; Dodek P; Leboeuf R; Briel M; Hashmi M; Camsooksai J; Shankar-Hari M; Baraki MK; Fugate K; Chua S; Marti C; Cohen D; Botton E; Agoritsas T; Siemieniuk RAC. BMJ (Clinical research ed.). 2018.

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis.

Schuetz P; Wirz Y; Sager R; Christ-Crain M; Stolz D; Tamm M; Bouadma L; Luyt CE; Wolff M; Chastre J; Tubach F; Kristoffersen KB; Burkhardt O; Welte T; Schroeder S; Nobre V; Wei L; Bucher HC; Annane D; Reinhart K; Falsey AR; Branche A; Damas P; Nijsten M; de Lange DW; Deliberato RO; Oliveira CF; Maravić-Stojković V; Verduri A; Beghé B; Cao B; Shehabi Y; Jensen JS; Corti C; van Oers JAH; Beishuizen A; Girbes ARJ; de Jong E; Briel M; Mueller B. The Lancet. Infectious diseases. 2018.

Funding characteristics of randomised clinical trials supported by the Swiss National Science Foundation: a retrospective cohort study.

Amstutz A; Schandelmaier S; Frei R; Surina J; Agarwal A; Alturki R; von Niederhäusern B; von Elm E; Briel M; On Behalf Of The MAking Randomized Trials Affordable Marta Group. Swiss Medical Weekly. 2018.

How to Conceptualize and Implement a PhD Program in Health Sciences-The Basel Approach.

Keller F; Dhaini S; Briel M; Henrichs S; Höchsmann C; Kalbermatten D; Künzli N; Mollet A; Puelacher C; Schmidt-Trucksäss A; von Niederhäusern B; De Geest S. Journal of medical education and curricular development. 2018.

Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials.

Schuetz P; Bolliger R; Merker M; Christ-Crain M; Stolz D; Tamm M; Luyt CE; Wolff M; Schroeder S; Nobre V; Reinhart K; Branche A; Damas P; Nijsten M; Deliberato RO; Verduri A; Beghé B; Cao B; Shehabi Y; Jensen JS; Beishuizen A; de Jong E; Briel M; Welte T; Mueller B. Expert review of anti-infective therapy. 2018.

Reply to Stern et al.

Briel M; Spoorenberg SMC; Bos WJW; Christ-Crain M. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2018.

Retrospective assessment of resource use and costs in two investigator-initiated randomized trials exemplified a comprehensive cost item list

Speich B.; von Niederhausern B.; Keiser J.; Furst T.; Kasenda B.; Christ-Crain M.; Hemkens L.G.; Pauli-Magnus C.; Schwenkglenks M.; Briel M.. Journal of clinical epidemiology. 2018.

Systematic review on costs and resource use of randomized clinical trials shows a lack of transparent and comprehensive data

Speich B.; von Niederhausern B.; Schur N.; Hemkens L.G.; Furst T.; Bhatnagar N.; Alturki R.; Agarwal A.; Kasenda B.; Pauli-Magnus C.; Schwenkglenks M.; Briel M.. Journal of clinical epidemiology. 2018.

Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey

Kahale L.A.; Diab B.; Brignardello-Petersen R.; Agarwal A.; Mustafa R.A.; Kwong J.; Neumann I.; Li L.; Lopes L.C.; Briel M.; Busse J.W.; Iorio A.; Vandvik P.O.; Alexander P.E.; Guyatt G.; Akl E.A.. Journal of clinical epidemiology. 2018.

Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts.

Agarwal A; Johnston BC; Vernooij RW; Carrasco-Labra A; Brignardello-Petersen R; Neumann I; Akl EA; Sun X; Briel M; Busse JW; Ebrahim S; Granados CE; Iorio A; Irfan A; Martínez García L; Mustafa RA; Ramirez-Morera A; Selva A; Solà I; Sanabrai AJ; Tikkinen KA; Vandvik PO; Zhang Y; Zazueta OE; Zhou Q; Schunemann HJ; Guyatt GH; Alonso-Coello P. Journal of clinical epidemiology. 2017.

Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: systematic review and meta-analysis.

Ewald H; Santini-Oliveira M; Bühler JE; Vuichard D; Schandelmaier S; Stöckle M; Briel M; Bucher HC; Hemkens LG. HIV clinical trials. 2017.

Discontinuation and non-publication of randomised clinical trials supported by the main public funding body in Switzerland: a retrospective cohort study.

Amstutz A; Schandelmaier S; Frei R; Surina J; Agarwal A; Olu KK; Alturki R; Von Niederhäusern B; Von Elm E; Briel M. BMJ Open. 2017.

Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients

Bally M.R.; Bounoure L.; Gomes F.; Blaser Yildirim P.Z.; Gloy V.L.; Briel M.; Schuetz P.. Cochrane Database of Systematic Reviews. 2017.

Effects of procalcitonin testing on antibiotic use and clinical outcomes in patients with upper respiratory tract infections. An individual patient data meta-analysis

Odermatt J.; Friedli N.; Kutz A.; Briel M.; Bucher H.C.; Christ-Crain M.; Burkhardt O.; Welte T.; Mueller B.; Schuetz P.. Clinical chemistry and laboratory medicine. 2017.

Generating evidence on a risk-based monitoring approach in the academic setting - lessons learned.

von Niederhäusern B; Orleth A; Schädelin S; Rawi N; Velkopolszky M; Becherer C; Benkert P; Satalkar P; Briel M; Pauli-Magnus C. BMC Medical Research Methodology. 2017.

GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale.

Welch VA; Akl EA; Guyatt G; Pottie K; Eslava-Schmalbach J; Ansari MT; de Beer H; Briel M; Dans T; Dans I; Hultcrantz M; Jull J; Katikireddi SV; Meerpohl J; Morton R; Mosdol A; Petkovic J; Schünemann HJ; Sharaf RN; Singh JA; Stanev R; Tonia T; Tristan M; Vitols S; Watine J; Tugwell P. Journal of clinical epidemiology. 2017.

GRADE equity guidelines 2: considering health equity in GRADE guideline development: equity extension of the guideline development checklist.

Akl EA; Welch V; Pottie K; Eslava-Schmalbach J; Darzi A; Sola I; Katikireddi SV; Singh J; Murad MH; Meerpohl J; Stanev R; Lang E; Matovinovic E; Shea B; Agoritsas T; Alexander PE; Snellman A; Brignardello-Petersen R; Gloss D; Thabane L; Shi C; Stein AT; Sharaf R; Briel M; Guyatt G; Schünemann H; Tugwell P. Journal of clinical epidemiology. 2017.

GRADE equity guidelines 3: considering health equity in GRADE guideline development: rating the certainty of synthesized evidence

Welch V.A.; Akl E.A.; Pottie K.; Ansari M.T.; Briel M.; Christensen R.; Dans A.; Dans L.; Eslava-Schmalbach J.; Guyatt G.; Hultcrantz M.; Jull J.; Katikireddi S.V.; Lang E.; Matovinovic E.; Meerpohl J.J.; Morton R.L.; Mosdol A.; Murad M.H.; Petkovic J.; Schunemann H.; Sharaf R.; Shea B.; Singh J.A.; Sola I.; Stanev R.; Stein A.; Thabaneii L.; Tonia T.; Tristan M.; Vitols S.; Watine J.; Tugwell P.. Journal of clinical epidemiology. 2017.

GRADE equity guidelines 4: considering health equity in GRADE guideline development: evidence to decision process.

Pottie K; Welch V; Morton R; Akl EA; Eslava-Schmalbach JH; Katikireddi V; Singh J; Moja L; Lang E; Magrini N; Thabane L; Stanev R; Matovinovic E; Snellman A; Briel M; Shea B; Tugwell P; Schunemann H; Guyatt G; Alonso-Coello P. Journal of clinical epidemiology. 2017.

GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence.

Guyatt GH; Ebrahim S; Alonso-Coello P; Johnston BC; Mathioudakis AG; Briel M; Mustafa RA; Sun X; Walter SD; Heels-Ansdell D; Neumann I; Kahale LA; Iorio A; Meerpohl J; Schünemann HJ; Akl EA. Journal of clinical epidemiology. 2017.

Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders.

Briel M; Elger B; von Elm E; Satalkar P. Swiss Medical Weekly. 2017.

Niacin for primary and secondary prevention of cardiovascular events

Schandelmaier S.; Briel M.; Saccilotto R.; Olu K.K.; Arpagaus A.; Hemkens L.G.; Nordmann A.J.. Cochrane Database of Systematic Reviews. 2017.

Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study.

Schandelmaier S; Tomonaga Y; Bassler D; Meerpohl JJ; von Elm E; You JJ; Bluemle A; Lamontagne F; Saccilotto R; Amstutz A; Bengough T; Stegert M; Olu KK; Tikkinen KAO; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Sun X; Busse JW; Ferreira-González I; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Guyatt G; Bucher HC; Kasenda B; Briel M. The Journal of pediatrics. 2017.

Premature trial discontinuation often not accurately reflected in registries: comparison of registry records with publications.

Alturki R; Schandelmaier S; Olu KK; von Niederhäusern B; Agarwal A; Frei R; Bhatnagar N; Hooft L; von Elm E; Briel M. Journal of clinical epidemiology. 2017.

Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study.

Odermatt J; Meili M; Hersberger L; Bolliger R; Christ-Crain M; Briel M; Bucher HC; Mueller B; Schuetz P. BMC cardiovascular disorders. 2017.

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

Schuetz P.; Wirz Y.; Sager R.; Christ-Crain M.; Stolz D.; Tamm M.; Bouadma L.; Luyt C.E.; Wolff M.; Chastre J.; Tubach F.; Kristoffersen K.B.; Burkhardt O.; Welte T.; Schroeder S.; Nobre V.; Wei L.; Bucher H.C.; Bhatnagar N.; Annane D.; Reinhart K.; Branche A.; Damas P.; Nijsten M.; de Lange D.W.; Deliberato R.O.; Lima S.S.; Maravic-Stojkovic V.; Verduri A.; Cao B.; Shehabi Y.; Beishuizen A.; Jensen J.-U.S.; Corti C.; Van Oers J.A.; Falsey A.R.; de Jong E.; Oliveira C.F.; Beghe B.; Briel M.; Mueller B.. Cochrane Database of Systematic Reviews. 2017.

Quantifying the bias in the estimated treatment effect in randomized trials having interim analyses and a rule for early stopping for futility.

Walter SD; Han H; Briel M; Guyatt GH. STATISTICS IN MEDICINE. 2017.

Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit.

Murad MH; Guyatt GH; Domecq JP; Vernooij RWM; Erwin PJ; Meerpohl JJ; Prutsky GJ; Akl EA; Mueller K; Bassler D; Schandelmaier S; Walter SD; Busse JW; Kasenda B; Pagano G; Pardo-Hernandez H; Montori VM; Wang Z; Briel M. Journal of clinical epidemiology. 2017.

Surgery for obstructive sleep apnoea in adults

Werz S.M.; Pfeifle M.; Schrader F.; Jurgens P.; Briel M.; Berg B.-I.. Cochrane Database of Systematic Reviews. 2017.

Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research.

Schmucker CM; Blümle A; Schell LK; Schwarzer G; Oeller P; Cabrera L; von Elm E; Briel M; Meerpohl JJ; OPEN consortium.. PLoS One. 2017.

The natriuretic peptide MR-proANP predicts all-cause mortality and adverse outcome in community patients: a 10-year follow-up study.

Odermatt J; Hersberger L; Bolliger R; Graedel L; Christ-Crain M; Briel M; Bucher HC; Mueller B; Schuetz P. Clinical chemistry and laboratory medicine. 2017.

The prognostic and predictive value of sstr<sub>2</sub>-immunohistochemistry and sstr<sub>2</sub>-targeted imaging in neuroendocrine tumors.

Brunner P; Jörg AC; Glatz K; Bubendorf L; Radojewski P; Umlauft M; Marincek N; Spanjol PM; Krause T; Dumont RA; Maecke HR; Müller-Brand J; Briel M; Schmitt A; Perren A; Walter MA. European journal of nuclear medicine and molecular imaging. 2017.

Towards the development of a comprehensive framework: Qualitative systematic survey of definitions of clinical research quality.

von Niederhäusern B; Schandelmaier S; Mi Bonde M; Brunner N; Hemkens LG; Rutquist M; Bhatnagar N; Guyatt GH; Pauli-Magnus C; Briel M. PLoS One. 2017.

Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

Kasenda B; von Elm E; You JJ; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Ebrahim S; Schandelmaier S; Sun X; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M. PLoS medicine. 2016.

An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules.

Stegert M; Kasenda B; von Elm E; You JJ; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Briel M; DISCO study group.. Journal of clinical epidemiology. 2016.

A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable.

Briel M; Olu KK; von Elm E; Kasenda B; Alturki R; Agarwal A; Bhatnagar N; Schandelmaier S. Journal of clinical epidemiology. 2016.

Bariatric surgery versus non-surgical treatment for obesity

Gloy, Viktoria L.; Briel, Matthias; Bhatt, Deepak L.; Kashyap, Sangeeta R.; Schauer, Philip R.; Mingrone, Geltrude; Bucher, Heiner C.; Nordmann, Alain J.. British journal of sports medicine. 2016.

Bias in dissemination of clinical research findings: structured OPEN framework of what, who and why, based on literature review and expert consensus.

Bassler D; Mueller KF; Briel M; Kleijnen J; Marusic A; Wager E; Antes G; von Elm E; Altman DG; Meerpohl JJ; OPEN Consortium.. BMJ Open. 2016.

Cardiovascular effects and safety of long-term colchicine treatment: Cochrane review and meta-analysis.

Hemkens LG; Ewald H; Gloy VL; Arpagaus A; Olu KK; Nidorf M; Glinz D; Nordmann AJ; Briel M. Heart (British Cardiac Society). 2016.

Cochrane corner: early statin therapy in acute coronary syndromes--what is the clinical benefit?

Nordmann A; Schwartz G; Vale N; Bucher HC; Briel M. Heart (British Cardiac Society). 2016.

Colchicine and Prevention of Cardiovascular Events.

Hemkens LG; Ewald H; Briel M. JAMA. 2016.

Colchicine for prevention of cardiovascular events.

Hemkens LG; Ewald H; Gloy VL; Arpagaus A; Olu KK; Nidorf M; Glinz D; Nordmann AJ; Briel M. The Cochrane database of systematic reviews. 2016.

Copeptin predicts 10-year all-cause mortality in community patients: a 10-year prospective cohort study.

Odermatt J; Bolliger R; Hersberger L; Ottiger M; Christ-Crain M; Briel M; Bucher HC; Mueller B; Schuetz P. Clinical chemistry and laboratory medicine. 2016.

Fibrates for primary prevention of cardiovascular disease events.

Jakob T; Nordmann AJ; Schandelmaier S; Ferreira-González I; Briel M. The Cochrane database of systematic reviews. 2016.

Fibrates for the primary prevention of cardiovascular disease

Nordmann, A.; Jakob, T.; Schandelmaier, S.; Ferreira-Gonzalez, I.; Briel, M.. European heart journal. 2016.

Guideline of guidelines: thromboprophylaxis for urological surgery.

Violette PD; Cartwright R; Briel M; Tikkinen KA; Guyatt GH. BJU international. 2016.

Infection biomarkers in primary care patients with acute respiratory tract infections-comparison of Procalcitonin and C-reactive protein

Meili M.; Kutz A.; Briel M.; Christ-Crain M.; Bucher H.C.; Mueller B.; Schuetz P.. BMC Pulmonary Medicine. 2016.

Influence of hospital characteristics on quality of care in patients with community-acquired pneumonia.

Straubhaar K; Schuetz P; Blum CA; Nigro N; Briel M; Christ-Crain M; Mueller B; Step Study Group. Swiss Medical Weekly. 2016.

In reply.

Mueller,Christian; Giannitsis,Evangelos; Lindahl,Bertil. Annals of emergency medicine. 2016.

Methods for detecting, quantifying, and adjusting for dissemination bias in meta-analysis are described.

Mueller KF; Meerpohl JJ; Briel M; Antes G; von Elm E; Lang B; Motschall E; Schwarzer G; Bassler D. Journal of clinical epidemiology. 2016.

Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS.

Kasenda B; Sauerbrei W; Royston P; Mercat A; Slutsky AS; Cook D; Guyatt GH; Brochard L; Richard JC; Stewart TE; Meade M; Briel M. BMJ Open. 2016.

Nutritional Support and Outcomes in Malnourished Medical Inpatients: A Systematic Review and Meta-analysis.

Bally MR; Blaser Yildirim PZ; Bounoure L; Gloy VL; Mueller B; Briel M; Schuetz P. JAMA internal medicine. 2016.

Other Measures of Event Reduction Reply

Ewald, Hannah; Gloy, Viktoria; Briel, Matthias. Deutsches Arzteblatt International. 2016.

Pathogen- and antibiotic-specific effects of prednisone in community-acquired pneumonia

Wirz S.A.; Blum C.A.; Schuetz P.; Albrich W.C.; Noppen C.; Mueller B.; Christ-Crain M.; Tarr P.E.; Blum C.A.; Nigro N.; Briel M.; Ullmer E.; Suter-Widmer I.; Winzeler B.; Bingisser R.; Elsaesser H.; Drozdov D.; Arici B.; Urwyler S.A.; Refardt J.; Thomann R.; Baumgartner C.; Duplain H.; Burki D.; Zimmerli W.; Rodondi N.. The European respiratory journal. 2016.

Planning and reporting of quality-of-life outcomes in cancer trials.

Schandelmaier S; Conen K; von Elm E; You JJ; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Sun X; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M; Kasenda B; DISCO study group.. Annals of Oncology. 2016.

Premature discontinuation of prospective clinical studies approved by a research ethics committee - A comparison of randomised and non-randomised studies

Blumle A.; Schandelmaier S.; Oeller P.; Kasenda B.; Briel M.; von Elm E.; Akl E.A.; Amstutz A.; Bassler D.; Bengough T.; Bucher H.C.; Burnand B.; Busse J.W.; Carrasco-Labra A.; Ebrahim S.; Faulhaber M.; Gloy V.; Ferreira-Gonzalez I.; Guyatt G.H.; Hemkens L.G.; Johnston B.C.; Lamontagne F.; Meerpohl J.J.; Mertz D.; Moja L.; Mulla S.; Neumann I.; Nordmann A.; Olu K.K.; Raatz H.; Rosenthal R.; Saccilotto R.; Schwenkglenks M.; Stegert M.; Sun X.; Tikkinen K.A.O.; Tomonaga Y.; Walter M.A.; Vandvik P.O.; You J.J.. PLoS One. 2016.

Premature discontinuation of randomized trials in critical and emergency care: A retrospective cohort study

Schandelmaier S.; Von Elm E.; You J.J.; Blumle A.; Tomonaga Y.; Lamontagne F.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.J.; Stegert M.; Olu K.K.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.M.; Mertz D.; Akl E.A.; Sun X.; Bassler D.; Busse J.W.; Ferreira-Gonzalez I.; Nordmann A.; Gloy V.; Raatz H.; Moja L.; Rosenthal R.; Ebrahim S.; Vandvik P.O.; Johnston B.C.; Walter M.A.; Burnand B.; Schwenkglenks M.; Hemkens L.G.; Cook D.J.; Meade M.O.; Bucher H.C.; Kasenda B.; Briel M.. Critical care medicine. 2016.

Reply: Somatostatin Receptor-Targeted Radiopeptide Therapy in Patients with Progressive Unresectable Meningioma.

Radojewski P; Dumont RA; Marincek N; Brunner P; Müller-Brand J; Maecke HR; Briel M; Walter MA. Journal of Nuclear Medicine. 2016.

Systematic reviews experience major limitations in reporting absolute effects

Alonso-Coello P.; Carrasco-Labra A.; Brignardello-Petersen R.; Neumann I.; Akl E.A.; Vernooij R.W.M.; Johnston B.C.; Sun X.; Briel M.; Busse J.W.; Ebrahim S.; Granados C.E.; Iorio A.; Irfan A.; Martinez Garcia L.; Mustafa R.A.; Ramirez-Morera A.; Selva A.; Sola I.; Sanabria A.J.; Tikkinen K.A.O.; Vandvik P.O.; Zazueta O.E.; Zhang Y.; Zhou Q.; Schunemann H.; Guyatt G.H.. Journal of clinical epidemiology. 2016.

The Clinical Effectiveness of Pneumococcal Conjugate Vaccines: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Ewald H; Briel M; Vuichard D; Kreutle V; Zhydkov A; Gloy V. Deutsches Arzteblatt International. 2016.

The reporting of studies using routinely collected health data was often insufficient.

Hemkens LG; Benchimol EI; Langan SM; Briel M; Kasenda B; Januel JM; Herrett E; von Elm E. Journal of clinical epidemiology. 2016.

Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol.

Schünemann HJ; Ventresca M; Crowther M; Briel M; Zhou Q; Garcia D; Lyman G; Noble S; Macbeth F; Griffiths G; DiNisio M; Iorio A; Beyene J; Mbuagbaw L; Neumann I; Van Es N; Brouwers M; Brozek J; Guyatt G; Levine M; Moll S; Santesso N; Streiff M; Baldeh T; Florez I; Gurunlu Alma O; Solh Z; Ageno W; Marcucci M; Bozas G; Zulian G; Maraveyas A; Lebeau B; Buller H; Evans J; McBane R; Bleker S; Pelzer U; Akl EA; IPDMA heparin use in cancer patients research group.. BMJ Open. 2016.

[About the certainty of study results. What p-value and confidence intervalls tell us on it].

Günther J; Briel M; Suter K. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Four numbers and a bit more basic knowledge of mathematics].

Günther J; Briel M; Suter K. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Four numbers and basic knowledge of mathematics].

Suter K; Briel M; Günther J. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Instructions for aggregated evidence: About reviews, systematic reviews and meta-analyses (part 2)].

Günther J; Briel M; Schindler B. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Instructions for aggregated evidence: Systematic reviews and meta-analyses (part 1)].

Schindler B; Briel M; Günther J. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Painting by number--Survival curves and Kaplan-Meier method].

Schindler B; Briel M; Günther J. Medizinische Monatsschrift fur Pharmazeuten. 2015.

[Why bother with regression models?].

Schindler B; Briel M; Günther J. Medizinische Monatsschrift fur Pharmazeuten. 2015.

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection.

Ewald H; Raatz H; Boscacci R; Furrer H; Bucher HC; Briel M. Cochrane Database of Systematic Reviews. 2015.

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial.

Blum CA; Nigro N; Briel M; Schuetz P; Ullmer E; Suter-Widmer I; Winzeler B; Bingisser R; Elsaesser H; Drozdov D; Arici B; Urwyler SA; Refardt J; Tarr P; Wirz S; Thomann R; Baumgartner C; Duplain H; Burki D; Zimmerli W; Rodondi N; Mueller B; Christ-Crain M. Lancet (London, England). 2015.

Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis.

D'Mello MJ; Ross SA; Briel M; Anand SS; Gerstein H; Paré G. Circ Cardiovasc Genet (ONLINE-AUSGABE). 2015.

Blood pressure targets for vasopressor therapy: a systematic review.

D'Aragon F; Belley-Cote EP; Meade MO; Lauzier F; Adhikari NK; Briel M; Lalu M; Kanji S; Asfar P; Turgeon AF; Fox-Robichaud A; Marshall JC; Lamontagne F; Canadian Critical Care Trials Group.. Shock (Augusta, Ga.). 2015.

Comparative effectiveness of tenofovir in treatment-naïve HIV-infected patients: systematic review and meta-analysis.

Hemkens, Lars G; Ewald, Hannah; Santini-Oliveira, Marilia; Bühler, Julian-Emanuel; Vuichard, Danielle; Schandelmaier, Stefan; Stöckle, Marcel; Briel, Matthias; Bucher, Heiner C. HIV clinical trials. 2015.

Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.

Rosenthal R; Kasenda B; Dell-Kuster S; von Elm E; You J; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla S; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Olu KK; Raatz H; Moja L; Ebrahim S; Schandelmaier S; Sun X; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M. Annals of Surgery. 2015.

Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis.

Siemieniuk RA; Meade MO; Alonso-Coello P; Briel M; Evaniew N; Prasad M; Alexander PE; Fei Y; Vandvik PO; Loeb M; Guyatt GH. Annals of internal medicine. 2015.

Corticosteroid therapy for pneumonia - Author's reply

Blum C.A.; Briel M.; Schuetz P.; Mueller B.; Christ-Crain M.. Lancet (London, England). 2015.

Driving pressure and survival in the acute respiratory distress syndrome.

Amato MB; Meade MO; Slutsky AS; Brochard L; Costa EL; Schoenfeld DA; Stewart TE; Briel M; Talmor D; Mercat A; Richard JC; Carvalho CR; Brower RG. New England Journal of Medicine. 2015.

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective.

Schuetz P; Balk R; Briel M; Kutz A; Christ-Crain M; Stolz D; Bouadma L; Wolff M; Kristoffersen KB; Wei L; Burkhardt O; Welte T; Schroeder S; Nobre V; Tamm M; Bhatnagar N; Bucher HC; Luyt CE; Chastre J; Tubach F; Mueller B; Lacey MJ; Ohsfeldt RL; Scheibling CM; Schneider JE. Clinical chemistry and laboratory medicine. 2015.

Evidence-informed recommendations to reduce dissemination bias in clinical research: conclusions from the OPEN (Overcome failure to Publish nEgative fiNdings) project based on an international consensus meeting.

Meerpohl JJ; Schell LK; Bassler D; Gallus S; Kleijnen J; Kulig M; La Vecchia C; Marušić A; Ravaud P; Reis A; Schmucker C; Strech D; Urrútia G; Wager E; Antes G; OPEN project consortium.. BMJ Open. 2015.

First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)--a systematic review and individual patient data meta-analysis.

Kasenda B; Ferreri AJ; Marturano E; Forst D; Bromberg J; Ghesquieres H; Ferlay C; Blay JY; Hoang-Xuan K; Pulczynski EJ; Fosså A; Okoshi Y; Chiba S; Fritsch K; Omuro A; O'Neill BP; Bairey O; Schandelmaier S; Gloy V; Bhatnagar N; Haug S; Rahner S; Batchelor TT; Illerhaus G; Briel M. Annals of Oncology. 2015.

Planning and reporting of quality-of-life outcomes in cancer trials.

Schandelmaier S; Conen K; von Elm E; You JJ; Blümle A; Tomonaga Y; Amstutz A; Briel M; Kasenda B; DISCO study group.. Annals of Oncology. 2015.

Prognostic value of procalcitonin in respiratory tract infections across clinical settings

Kutz A.; Briel M.; Christ-Crain M.; Stolz D.; Bouadma L.; Wolff M.; Kristoffersen K.B.; Wei L.; Burkhardt O.; Welte T.; Schroeder S.; Nobre V.; Tamm M.; Bhatnagar N.; Bucher H.C.; Luyt C.-E.; Chastre J.; Tubach F.; Mueller B.; Schuetz P.. Critical care (London, England). 2015.

Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the Reduction in the Use of Corticosteroids in Exacerbated COPD (REDUCE) trial.

Schuetz P; Leuppi JD; Bingisser R; Bodmer M; Briel M; Drescher T; Duerring U; Henzen C; Leibbrandt Y; Maier S; Miedinger D; Mueller B; Scherr A; Schindler C; Stoeckli R; Viatte S; von Garnier C; Tamm M; Rutishauser J. European journal of endocrinology. 2015.

Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.

Akl EA; Carrasco-Labra A; Brignardello-Petersen R; Neumann I; Johnston BC; Sun X; Briel M; Busse JW; Ebrahim S; Granados CE; Iorio A; Irfan A; Martínez García L; Mustafa RA; Ramírez-Morera A; Selva A; Solà I; Sanabria AJ; Tikkinen KA; Vandvik PO; Vernooij RW; Zazueta OE; Zhou Q; Guyatt GH; Alonso-Coello P. BMJ Open. 2015.

Somatostatin receptor-targeted radiopeptide therapy with 90Y-DOTATOC and 177Lu-DOTATOC in progressive meningioma: long-term results of a phase II clinical trial.

Marincek N; Radojewski P; Dumont RA; Brunner P; Müller-Brand J; Maecke HR; Briel M; Walter MA. Journal of Nuclear Medicine. 2015.

Survival after somatostatin based radiopeptide therapy with (90)Y-DOTATOC vs. (90)Y-DOTATOC plus (177)Lu-DOTATOC in metastasized gastrinoma.

Dumont RA; Seiler D; Marincek N; Brunner P; Radojewski P; Rochlitz C; Müller-Brand J; Maecke HR; Briel M; Walter MA. American journal of nuclear medicine and molecular imaging. 2015.

The number needed to treat (NNT) and the number needed to harm (NNH)

Suter K.; Briel M.; Gunther J.. Medizinische Monatsschrift fur Pharmazeuten. 2015.

The Principle of Intention-to-Treat and Ambiguous Dropouts

Briel,M; Montori,VM; Durieux,P; Devereaux,PJ; Guyatt,GH. . 2015.

Towards tailored radiopeptide therapy.

Radojewski P; Dumont R; Marincek N; Brunner P; Mäcke HR; Müller-Brand J; Briel M; Walter MA. European journal of nuclear medicine and molecular imaging. 2015.

Understanding Class Effects

Mills,EJ; Gardner,D; Thorlund,K; Briel,M; Bucher,H; Bryan,S; Hutton,B; Guyatt,GH. . 2015.

A users' guide to understanding therapeutic substitutions.

Mills EJ; Gardner D; Thorlund K; Briel M; Bryan S; Hutton B; Guyatt GH. Journal of clinical epidemiology. 2014.

Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease

Reinhard M.; Schwarzer G.; Briel M.; Altamura C.; Palazzo P.; King A.; Bornstein N.M.; Petersen N.; Motschall E.; Hetzel A.; Marshall R.S.; Klijn C.J.M.; Silvestrini M.; Markus H.S.; Vernieri F.. Neurology. 2014.

Colchicine for prevention of cardiovascular events

Hemkens L.G.; Gloy V.L.; Olu K.K.; Nordmann A.J.; Briel M.. Cochrane Database of Systematic Reviews. 2014.

Correction: A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): A study protocol

Alonso-Coello P.; Carrasco-Labra A.; Brignardello-Petersen R.; Neumann I.; Akl E.A.; Sun X.; Johnston B.C.; Briel M.; Busse J.W.; Glujovsky D.; Granados C.E.; Iorio A.; Irfan A.; Garcia L.M.; Mustafa R.A.; Ramirez-Morera A.; Sola I.; Tikkinen K.A.O.; Ebrahim S.; Vandvik P.O.; Zhang Y.; Selva A.; Sanabria A.J.; Zazueta O.E.; Vernooij R.W.M.; Schunemann H.J.; Guyatt G.H.. Systematic reviews. 2014.

Corticosteroid treatment for community-acquired pneumonia--the STEP trial: study protocol for a randomized controlled trial.

Blum CA; Nigro N; Winzeler B; Suter-Widmer I; Schuetz P; Briel M; Bingisser R; Zimmerli W; Ullmer E; Elsaesser H; Tarr P; Wirz S; Thomann R; Hofmann E; Rodondi N; Duplain H; Burki D; Mueller B; Christ-Crain M. Trials. 2014.

Dissemination bias in systematic reviews of animal research: a systematic review.

Mueller KF; Briel M; Strech D; Meerpohl JJ; Lang B; Motschall E; Gloy V; Lamontagne F; Bassler D. PLoS One. 2014.

Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients

Schuetz P.; Blaser Yildirim P.Z.; Gloy V.L.; Briel M.; Bally M.R.. Cochrane Database of Systematic Reviews. 2014.

How to write a surgical clinical research protocol: literature review and practical guide.

Rosenthal R; Schäfer J; Briel M; Bucher HC; Oertli D; Dell-Kuster S. American Journal of Surgery. 2014.

Impact of missing participant data for dichotomous outcomes on pooled effect estimates in systematic reviews: a protocol for a methodological study.

Akl EA; Kahale LA; Agarwal A; Al-Matari N; Ebrahim S; Alexander PE; Briel M; Brignardello-Petersen R; Busse JW; Diab B; Iorio A; Kwong J; Li L; Lopes LC; Mustafa R; Neumann I; Tikkinen KA; Vandvik PO; Zhang Y; Alonso-Coello P; Guyatt G. Systematic reviews. 2014.

Investigation of continuous effect modifiers in a meta-analysis on higher versus lower PEEP in patients requiring mechanical ventilation--protocol of the ICEM study.

Kasenda B; Sauerbrei W; Royston P; Briel M. Systematic reviews. 2014.

Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol.

Wu D; Akl EA; Guyatt GH; Devereaux PJ; Brignardello-Petersen R; Prediger B; Patel K; Patel N; Lu T; Zhang Y; Falavigna M; Santesso N; Mustafa RA; Zhou Q; Briel M; Schünemann HJ. Trials. 2014.

Prevalence, characteristics, and publication of discontinued randomized trials

Kasenda B.; Von Elm E.; You J.; Blumle A.; Tomonaga Y.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.J.; Stegert M.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.M.; Mertz D.; Akl E.A.; Bassler D.; Busse J.W.; Ferreira-Gonzalez I.; Lamontagne F.; Nordmann A.; Gloy V.; Raatz H.; Moja L.; Rosenthal R.; Ebrahim S.; Schandelmaier S.; Xin S.; Vandvik P.O.; Johnston B.C.; Walter M.A.; Burnand B.; Schwenkglenks M.; Hemkens L.G.; Bucher H.C.; Guyatt G.H.; Briel M.. JAMA. 2014.

Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumours.

Romer A; Seiler D; Marincek N; Brunner P; Koller MT; Ng QK; Maecke HR; Müller-Brand J; Rochlitz C; Briel M; Schindler C; Walter MA. European journal of nuclear medicine and molecular imaging. 2014.

Statins for acute coronary syndrome

Vale N.; Nordmann A.J.; Schwartz G.G.; de Lemos J.; Colivicchi F.; den Hartog F.; Ostadal P.; Macin S.M.; Liem A.H.; Mills E.J.; Bhatnagar N.; Bucher H.C.; Briel M.. Cochrane Database of Systematic Reviews. 2014.

Statins for acute coronary syndrome.

Vale,Noah; Nordmann,Alain J; Schwartz,Gregory G; de Lemos,James; Colivicchi,Furio; den Hartog,Frank; Ostadal,Petr; Macin,Stella M; Liem,Anho H; Mills,Edward J; Bhatnagar,Neera; Bucher,Heiner C; Briel,Matthias. Cochrane Database of Systematic Reviews. 2014.

Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.

Kasenda B; Schandelmaier S; Sun X; von Elm E; You J; Blümle A; Tomonaga Y; Saccilotto R; Amstutz A; Bengough T; Meerpohl JJ; Stegert M; Olu KK; Tikkinen KA; Neumann I; Carrasco-Labra A; Faulhaber M; Mulla SM; Mertz D; Akl EA; Bassler D; Busse JW; Ferreira-González I; Lamontagne F; Nordmann A; Gloy V; Raatz H; Moja L; Rosenthal R; Ebrahim S; Vandvik PO; Johnston BC; Walter MA; Burnand B; Schwenkglenks M; Hemkens LG; Bucher HC; Guyatt GH; Briel M; DISCO Study Group.. BMJ (Clinical research ed.). 2014.

[Is procalcitonin determination for control of antibiotic therapy in acute respiratory infections of value?].

Schütz P; Müller B; Briel M. Praxis. 2013.

Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers.

Akl EA; Johnston BC; Alonso-Coello P; Neumann I; Ebrahim S; Briel M; Cook DJ; Guyatt GH. PLoS One. 2013.

A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol.

Alonso-Coello P; Carrasco-Labra A; Brignardello-Petersen R; Neumann I; Akl EA; Sun X; Johnston BC; Briel M; Busse JW; Glujovsky D; Granados CE; Iorio A; Irfan A; Martínez García L; Mustafa RA; Ramirez-Morera A; Solà I; Tikkinen KA; Ebrahim S; Vandvik PO; Zhang Y; Selva A; Sanabria AJ; Zazueta OE; Vernooij RW; Schünemann HJ; Guyatt GH. Systematic reviews. 2013.

A protocol for a systematic review on the impact of unpublished studies and studies published in the gray literature in meta-analyses.

Schmucker C; Bluemle A; Briel M; Portalupi S; Lang B; Motschall E; Schwarzer G; Bassler D; Mueller KF; von Elm E; Meerpohl JJ; OPEN Consortium.. Systematic reviews. 2013.

A systematic review of nonabsorbable, absorbable, and steroid-impregnated spacers following endoscopic sinus surgery.

Zhao X; Grewal A; Briel M; Lee JM. International Forum of Allergy & Rhinology. 2013.

Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials.

Gloy VL; Briel M; Bhatt DL; Kashyap SR; Schauer PR; Mingrone G; Bucher HC; Nordmann AJ. BMJ (Clinical research ed.). 2013.

BARIATRIC SURGERY VERSUS NON-SURGICAL TREATMENT FOR OBESITY: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Gloy, V. L.; Briel, M.; Bhatt, D.; Kashyap, S.; Schauer, P.; Mingrone, G.; Bucher, H. C.; Nordmann, A. J.. Cardiology. 2013.

Blockade of the renin-angiotensin-aldosterone system (RAAS) for primary prevention of non-valvular atrial fibrillation: a systematic review and meta analysis of randomized controlled trials.

Khatib R; Joseph P; Briel M; Yusuf S; Healey J. International Journal of Cardiology. 2013.

Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections.

Schuetz P; Briel M; Mueller B. JAMA. 2013.

Commentaries on 'Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections' with a response from the review authors

Sabhaney V.; Enarson P.; Irwin A.D.; Carrol E.D.; Schuetz P.; Briel M.; Bucher H.C.; Mueller B.. Evidence-based child health : a Cochrane review journal. 2013.

Defining publication bias: protocol for a systematic review of highly cited articles and proposal for a new framework.

Müller KF; Briel M; D'Amario A; Kleijnen J; Marusic A; Wager E; Antes G; von Elm E; Lang B; Motschall E; Gloy V; Schwarzer G; Altman D; Meerpohl JJ; Bassler D. Systematic reviews. 2013.

Detecting, quantifying and adjusting for publication bias in meta-analyses: protocol of a systematic review on methods.

Mueller KF; Meerpohl JJ; Briel M; Antes G; von Elm E; Lang B; Gloy V; Motschall E; Schwarzer G; Bassler D. Systematic reviews. 2013.

Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design.

Prutsky GJ; Domecq JP; Erwin PJ; Briel M; Montori VM; Akl EA; Meerpohl JJ; Bassler D; Schandelmaier S; Walter SD; Zhou Q; Coello PA; Moja L; Walter M; Thorlund K; Glasziou P; Kunz R; Ferreira-Gonzalez I; Busse J; Sun X; Kristiansen A; Kasenda B; Qasim-Agha O; Pagano G; Pardo-Hernandez H; Urrutia G; Murad MH; Guyatt G. Trials. 2013.

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

Schuetz P; Müller B; Christ-Crain M; Stolz D; Tamm M; Bouadma L; Luyt CE; Wolff M; Chastre J; Tubach F; Kristoffersen KB; Burkhardt O; Welte T; Schroeder S; Nobre V; Wei L; Bhatnagar N; Bucher HC; Briel M. Evidence-based child health : a Cochrane review journal. 2013.

Publication bias in animal research: a systematic review protocol.

Briel M; Müller KF; Meerpohl JJ; von Elm E; Lang B; Motschall E; Gloy V; Lamontagne F; Schwarzer G; Bassler D; OPEN Consortium.. Systematic reviews. 2013.

Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis.

Bala MM; Akl EA; Sun X; Bassler D; Mertz D; Mejza F; Vandvik PO; Malaga G; Johnston BC; Dahm P; Alonso-Coello P; Diaz-Granados N; Srinathan SK; Hassouneh B; Briel M; Busse JW; You JJ; Walter SD; Altman DG; Guyatt GH. Journal of clinical epidemiology. 2013.

Reflections on meta-analyses involving trials stopped early for benefit: is there a problem and if so, what is it?

Bassler D; Montori VM; Briel M; Glasziou P; Walter SD; Ramsay T; Guyatt G. STATISTICAL METHODS IN MEDICAL RESEARCH. 2013.

Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.

Leuppi JD; Schuetz P; Bingisser R; Bodmer M; Briel M; Drescher T; Duerring U; Henzen C; Leibbrandt Y; Maier S; Miedinger D; Müller B; Scherr A; Schindler C; Stoeckli R; Viatte S; von Garnier C; Tamm M; Rutishauser J. JAMA. 2013.

Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study.

Marincek N; Jörg AC; Brunner P; Schindler C; Koller MT; Rochlitz C; Müller-Brand J; Maecke HR; Briel M; Walter MA. Journal of Translational Medicine. 2013.

Substitutes of structural and non-structural autologous bone grafts in hindfoot arthrodeses and osteotomies: a systematic review.

Müller MA; Frank A; Briel M; Valderrabano V; Vavken P; Entezari V; Mehrkens A. BMC MUSCULOSKELETAL DISORDERS. 2013.

Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.

Alberton M; Wu P; Druyts E; Briel M; Mills EJ. QJM : monthly journal of the Association of Physicians. 2012.

Cohort study of somatostatin-based radiopeptide therapy with [(90)Y-DOTA]-TOC versus [(90)Y-DOTA]-TOC plus [(177)Lu-DOTA]-TOC in neuroendocrine cancers.

Villard L; Romer A; Marincek N; Brunner P; Koller MT; Schindler C; Ng QK; Mäcke HR; Müller-Brand J; Rochlitz C; Briel M; Walter MA. Journal of Clinical Oncology. 2012.

Credibility of claims of subgroup effects in randomised controlled trials: systematic review.

Sun X; Briel M; Busse JW; You JJ; Akl EA; Mejza F; Bala MM; Bassler D; Mertz D; Diaz-Granados N; Vandvik PO; Malaga G; Srinathan SK; Dahm P; Johnston BC; Alonso-Coello P; Hassouneh B; Walter SD; Heels-Ansdell D; Bhatnagar N; Altman DG; Guyatt GH. BMJ (Clinical research ed.). 2012.

Dipeptidyl Peptidase-4 Inhibitors May Reduce the Risk of Major Adverse Cardiovascular Events and All-cause Mortality In Patients With Type 2 Diabetes: Meta-analyses Oof Randomized Controlled Trials

Sun, Xin; Hazzan, Afeez A.; Bala, Malgorzata; Russe, Jason W.; Johnston, Bradley C.; Carrasco-Labra, Alonso; Jankowski, Milosz; Neumann, Ignacio; Ferreira-Gonzalez, Ignacio; Fernandez-Balsells, Merce; Rios, Lorena; Bassler, Dirk; Briel, Matthias; Lopes, Luciane; Nordmann, Alain; Tikkinen, Kari A.; Ismaila, Nofisat; Zhou, Qi; Mukherjee, Jayanti; Frederich, Robert; Iqbal, Nayyar; Walter, Stephen; Guyatt, Gordon. Circulation. 2012.

Fibrates for primary prevention of cardiovascular disease events.

Nordmann AJ; Ferreira-González I; Kasenda B; Saccilotto R; Bassler D; Bhatnagar N; Briel M. The Cochrane database of systematic reviews. 2012.

Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature.

Alshurafa M; Briel M; Akl EA; Haines T; Moayyedi P; Gentles SJ; Rios L; Tran C; Bhatnagar N; Lamontagne F; Walter SD; Guyatt GH. PLoS One. 2012.

Learning from failure - Rationale and design for a study about discontinuation of randomized trials (DISCO study)

Kasenda B.; Von Elm E.B.; You J.; Blumle A.; Tomonaga Y.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.; Stegert M.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.; Mertz D.; Akl E.A.; Bassler D.; Busse J.W.; Ferreira-Gonzalez I.; Lamontagne F.; Nordmann A.; Rosenthal R.; Schandelmaier S.; Sun X.; Vandvik P.O.; Johnston B.C.; Walter M.A.; Burnand B.; Schwenkglenks M.; Bucher H.C.; Guyatt G.H.; Briel M.. BMC Medical Research Methodology. 2012.

Meta-analyses: what they can and cannot do.

Nordmann AJ; Kasenda B; Briel M. Swiss Medical Weekly. 2012.

Mould-active compared with fluconazole prophylaxis to prevent invasive fungal diseases in cancer patients receiving chemotherapy or haematopoietic stem-cell transplantation: a systematic review and meta-analysis of randomised controlled trials

Ethier, M. C.; Science, M.; Beyene, J.; Briel, M.; Lehrnbecher, T.; Sung, L.. British journal of cancer. 2012.

Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review.

Akl EA; Briel M; You JJ; Sun X; Johnston BC; Busse JW; Mulla S; Lamontagne F; Bassler D; Vera C; Alshurafa M; Katsios CM; Zhou Q; Cukierman-Yaffe T; Gangji A; Mills EJ; Walter SD; Cook DJ; Schünemann HJ; Altman DG; Guyatt GH. BMJ (Clinical research ed.). 2012.

Problems of stopping trials early.

Guyatt GH; Briel M; Glasziou P; Bassler D; Montori VM. BMJ (Clinical research ed.). 2012.

Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis.

Schuetz P; Briel M; Christ-Crain M; Stolz D; Bouadma L; Wolff M; Luyt CE; Chastre J; Tubach F; Kristoffersen KB; Wei L; Burkhardt O; Welte T; Schroeder S; Nobre V; Tamm M; Bhatnagar N; Bucher HC; Mueller B. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2012.

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

Schuetz P; Müller B; Christ-Crain M; Stolz D; Tamm M; Bouadma L; Luyt CE; Wolff M; Chastre J; Tubach F; Kristoffersen KB; Burkhardt O; Welte T; Schroeder S; Nobre V; Wei L; Bhatnagar N; Bucher HC; Briel M. Cochrane Database of Systematic Reviews. 2012.

Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid.

Akl EA; Sun X; Busse JW; Johnston BC; Briel M; Mulla S; You JJ; Bassler D; Lamontagne F; Vera C; Alshurafa M; Katsios CM; Heels-Ansdell D; Zhou Q; Mills E; Guyatt GH. Journal of clinical epidemiology. 2012.

Statins: pleiotropic, but less than previously thought.

Nordmann AJ; Briel M. European heart journal. 2012.

The dangers of stopping a trial too early.

Briel M; Bassler D; Wang AT; Guyatt GH; Montori VM. The Journal of bone and joint surgery. American volume. 2012.

The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis.

Fuchs M; Briel M; Daikeler T; Walker UA; Rasch H; Berg S; Ng QK; Raatz H; Jayne D; Kötter I; Blockmans D; Cid MC; Prieto-González S; Lamprecht P; Salvarani C; Karageorgaki Z; Watts R; Luqmani R; Müller-Brand J; Tyndall A; Walter MA. European journal of nuclear medicine and molecular imaging. 2012.

Updated evidence on early statin therapy for acute coronary syndromes: meta-analysis of 18 randomized trials involving over 14,000 patients.

Briel M; Vale N; Schwartz GG; de Lemos JA; Colivicchi F; den Hartog FR; Ostadal P; Macin SM; Liem A; Mills E; Bhatnagar N; Bucher HC; Nordmann AJ. International Journal of Cardiology. 2012.

Economic evaluation of reamed versus unreamed intramedullary nailing in patients with closed and open tibial fractures: results from the study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures (SPRINT).

SPRINT Investigators.; Briel M; Sprague S; Heels-Ansdell D; Guyatt G; Bhandari M; Blackhouse G; Sanders D; Schemitsch E; Swiontkowski M; Tornetta P 3rd; Walter SD; Goeree R. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2011.

Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170,255 patients from 76 randomized trials.

Mills EJ; Wu P; Chong G; Ghement I; Singh S; Akl EA; Eyawo O; Guyatt G; Berwanger O; Briel M. QJM : monthly journal of the Association of Physicians. 2011.

Intensive statin therapy compared with moderate dosing for prevention of cardiovascular events: a meta-analysis of &gt;40 000 patients.

Mills EJ; O'Regan C; Eyawo O; Wu P; Mills F; Berwanger O; Briel M. European heart journal. 2011.

Meta-analysis comparing Mediterranean to low-fat diets for modification of cardiovascular risk factors.

Nordmann AJ; Suter-Zimmermann K; Bucher HC; Shai I; Tuttle KR; Estruch R; Briel M. The American journal of medicine. 2011.

Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms.

Schuetz P; Chiappa V; Briel M; Greenwald JL. Archives of internal medicine. 2011.

Randomisation to protect against selection bias in healthcare trials

Odgaard-Jensen J.; Vist G.E.; Timmer A.; Kunz R.; Akl E.A.; Schunemann H.; Briel M.; Nordmann A.J.; Pregno S.; Oxman A.D.. Cochrane Database of Systematic Reviews. 2011.

Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine cancers.

Imhof A; Brunner P; Marincek N; Briel M; Schindler C; Rasch H; Mäcke HR; Rochlitz C; Müller-Brand J; Walter MA. Journal of Clinical Oncology. 2011.

Statins for acute coronary syndrome.

Vale N; Nordmann AJ; Schwartz GG; de Lemos J; Colivicchi F; den Hartog F; Ostadal P; Macin SM; Liem AH; Mills E; Bhatnagar N; Bucher HC; Briel M. Cochrane Database of Systematic Reviews. 2011.

The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review

Sun, Xin; Briel, Matthias; Busse, Jason W.; You, John J.; Akl, Elie A.; Mejza, Filip; Bala, Malgorzata M.; Bassler, Dirk; Mertz, Dominik; Diaz-Granados, Natalia; Vandvik, Per Olav; Malaga, German; Srinathan, Sadeesh K.; Dahm, Philipp; Johnston, Bradley C.; Alonso-Coello, Pablo; Hassouneh, Basil; Truong, Jessica; Dattani, Neil D.; Walter, Stephen D.; Heels-Ansdell, Diane; Bhatnagar, Neera; Altman, Douglas G.; Guyatt, Gordon H.. BMJ (Clinical research ed.). 2011.

Vasopressor administration and sepsis: a survey of Canadian intensivists.

Lamontagne F; Cook DJ; Adhikari NKJ; Briel M; Duffett M; Kho ME; Burns KEA; Guyatt G; Turgeon AF; Zhou Q; Meade MO. Journal of critical care. 2011.

Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: a meta-analysis of randomized controlled trials.

Lamontagne F; Briel M; Guyatt GH; Cook DJ; Bhatnagar N; Meade M. Journal of critical care. 2010.

Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.

Briel M; Meade M; Mercat A; Brower RG; Talmor D; Walter SD; Slutsky AS; Pullenayegum E; Zhou Q; Cook D; Brochard L; Richard JC; Lamontagne F; Bhatnagar N; Stewart TE; Guyatt G. JAMA. 2010.

Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction.

Briel M. Evidence-based nursing. 2010.

Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses.

Sun X; Briel M; Walter SD; Guyatt GH. BMJ (Clinical research ed.). 2010.

Short versus conventional term glucocorticoid therapy in acute exacerbation of chronic obstructive pulmonary disease - the "REDUCE" trial.

Schuetz P; Leuppi JD; Tamm M; Briel M; Bingisser R; Dürring U; Müller B; Schindler C; Viatte S; Rutishauser J. Swiss Medical Weekly. 2010.

Stopping randomized trials early for benefit and estimation of treatment effects: Systematic review and meta-regression analysis

Bassler D.; Briel M.; Montori V.M.; Lane M.; Glasziou P.; Zhou Q.; Heels-Ansdell D.; Walter S.D.; Guyatt G.H.; Flynn D.N.; Elamin M.B.; Murad M.H.; Abu Elnour N.O.; Lampropulos J.F.; Sood A.; Mullan R.J.; Erwin P.J.; Bankhead C.R.; Perera R.; Culebro C.R.; You J.J.; Mulla S.M.; Kaur J.; Nerenberg K.A.; Schunemann H.; Cook D.J.; Lutz K.; Ribic C.M.; Vale N.; Malaga G.; Akl E.A.; Ferreira-Gonzalez I.; Alonso-Coello P.; Urrutia G.; Kunz R.; Bucher H.C.; Nordmann A.J.; Raatz H.; Da Silva S.A.; Tuche F.; Strahm B.; Djulbegovic B.; Adhikari N.K.J.; Mills E.J.; Gwadry-Sridhar F.; Kirpalani H.; Soares H.P.; Karanicolas P.J.; Burns K.E.A.; Vandvik P.O.; Coto-Yglesias F.; Chrispim P.P.M.; Ramsay T.. JAMA. 2010.

Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis.

Lamontagne F; Briel M; Duffett M; Fox-Robichaud A; Cook DJ; Guyatt G; Lesur O; Meade MO. Critical care medicine. 2010.

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis.

Briel M; Ferreira-Gonzalez I; You JJ; Karanicolas PJ; Akl EA; Wu P; Blechacz B; Bassler D; Wei X; Sharman A; Whitt I; Alves da Silva S; Khalid Z; Nordmann AJ; Zhou Q; Walter SD; Vale N; Bhatnagar N; O'Regan C; Mills EJ; Bucher HC; Montori VM; Guyatt GH. BMJ (Clinical research ed.). 2009.

Choice of data extraction tools for systematic reviews depends on resources and review complexity.

Elamin MB; Flynn DN; Bassler D; Briel M; Alonso-Coello P; Karanicolas PJ; Guyatt GH; Malaga G; Furukawa TA; Kunz R; Schünemann H; Murad MH; Barbui C; Cipriani A; Montori VM. Journal of clinical epidemiology. 2009.

Cost-effectiveness of drug-eluting stents in a US Medicare setting:a cost-utility analysis with 3-year clinical follow-up data.

Bischof M; Briel M; Bucher HC; Nordmann A. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2009.

LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact.

Akl EA; Briel M; You JJ; Lamontagne F; Gangji A; Cukierman-Yaffe T; Alshurafa M; Sun X; Nerenberg KA; Johnston BC; Vera C; Mills EJ; Bassler D; Salazar A; Bhatnagar N; Busse JW; Khalid Z; Walter S; Cook DJ; Schünemann HJ; Altman DG; Guyatt GH. Trials. 2009.

Prescribed medications and pharmacy interventions for acute respiratory tract infections in Swiss primary care.

Hersberger KE; Botomino A; Sarkar R; Tschudi P; Bucher HC; Briel M. Journal of clinical pharmacy and therapeutics. 2009.

Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2).

Briel M; Lane M; Montori VM; Bassler D; Glasziou P; Malaga G; Akl EA; Ferreira-Gonzalez I; Alonso-Coello P; Urrutia G; Kunz R; Culebro CR; da Silva SA; Flynn DN; Elamin MB; Strahm B; Murad MH; Djulbegovic B; Adhikari NK; Mills EJ; Gwadry-Sridhar F; Kirpalani H; Soares HP; Abu Elnour NO; You JJ; Karanicolas PJ; Bucher HC; Lampropulos JF; Nordmann AJ; Burns KE; Mulla SM; Raatz H; Sood A; Kaur J; Bankhead CR; Mullan RJ; Nerenberg KA; Vandvik PO; Coto-Yglesias F; Schünemann H; Tuche F; Chrispim PP; Cook DJ; Lutz K; Ribic CM; Vale N; Erwin PJ; Perera R; Zhou Q; Heels-Ansdell D; Ramsay T; Walter SD; Guyatt GH. Trials. 2009.

Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.

Sun X; Briel M; Busse JW; Akl EA; You JJ; Mejza F; Bala M; Diaz-Granados N; Bassler D; Mertz D; Srinathan SK; Vandvik PO; Malaga G; Alshurafa M; Dahm P; Alonso-Coello P; Heels-Ansdell DM; Bhatnagar N; Johnston BC; Wang L; Walter SD; Altman DG; Guyatt GH. Trials. 2009.

Drug-eluting stents from a Medicare payer perspective: Cost-utility analysis with 4-year clinical meta-analysis data

Bischof, M.; Briel, M.; Bucher, H. C.; Nordmann, A.. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2008.

Early stopping of randomized clinical trials for overt efficacy is problematic.

Bassler D; Montori VM; Briel M; Glasziou P; Guyatt G. Journal of clinical epidemiology. 2008.

Hemodynamic performance of stentless versus stented valves: a systematic review and meta-analysis.

Payne DM; Koka HP; Karanicolas PJ; Chu MW; Nagpal AD; Briel M; Schünemann HJ; Lonn EM. JOURNAL OF CARDIAC SURGERY. 2008.

Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care.

Briel M; Schuetz P; Mueller B; Young J; Schild U; Nusbaumer C; Périat P; Bucher HC; Christ-Crain M. Archives of internal medicine. 2008.

Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections

Schuetz P.; Briel M.; Christ-Crain M.; Wolbers M.; Stolz D.; Tamm M.; Bucher H.; Muller B.. Cochrane Database of Systematic Reviews. 2008.

The master-question: meta-analyses and stopped-early randomized trials - a problem? - Reply

Bassler, Dirk; Ferreira-Gonzalez, Ignacio; Briel, Matthias; Cook, Deborah J.; Devereaux, P. J.; Heels-Ansdell, Diane; Kirpalani, Haresh; Meade, Maureen O.; Montori, Victor M.; Rozenberg, Anna; Schunemann, Holger J.; Guyatt, Gordon H.. Journal of clinical epidemiology. 2008.

Cost-effectiveness of drug eluting stents in a US setting: cost-utility analysis with a decision analytic model using meta-analysis data with 3 year follow-up

Nordmann, A. J.; Bischof, M.; Briel, M.; Bucher, H. C.. European heart journal. 2007.

Effects of antithyroid drugs on radioiodine treatment: systematic review and meta-analysis of randomised controlled trials.

Walter MA; Briel M; Christ-Crain M; Bonnema SJ; Connell J; Cooper DS; Bucher HC; Müller-Brand J; Müller B. BMJ (Clinical research ed.). 2007.

Shared-decision making in general practice: do patients with respiratory tract infections actually want it?

Briel M; Young J; Tschudi P; Hugenschmidt C; Bucher HC; Langewitz W. Swiss Medical Weekly. 2007.

Systematic reviewers neglect bias that results from trials stopped early for benefit.

Bassler D; Ferreira-Gonzalez I; Briel M; Cook DJ; Devereaux PJ; Heels-Ansdell D; Kirpalani H; Meade MO; Montori VM; Rozenberg A; Schünemann HJ; Guyatt GH. Journal of clinical epidemiology. 2007.

The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer.

Karanicolas PJ; Davies E; Kunz R; Briel M; Koka HP; Payne DM; Smith SE; Hsu HP; Lin PW; Bloechle C; Paquet KJ; Guyatt GH. Annals of surgical oncology. 2007.

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection.

Briel M; Bucher HC; Boscacci R; Furrer H. Cochrane Database of Systematic Reviews. 2006.

Communication training and antibiotic use in acute respiratory tract infections. A cluster randomised controlled trial in general practice.

Briel M; Langewitz W; Tschudi P; Young J; Hugenschmidt C; Bucher HC. Swiss Medical Weekly. 2006.

Definition of low-fat diets - In reply

Nordmann, Alain J.; Yancy, William S., Jr.; Keller, Ulrich; Briel, Matthias; Bucher, Heiner C.. Archives of internal medicine. 2006.

Economic evaluation of drug eluting stents: Cost-utility analysis

Bischof, M.; Briel, M.; Bucher, H. C.; Nordmann, A.. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2006.

Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: a meta-analysis of randomized controlled trials.

Briel M; Schwartz GG; Thompson PL; de Lemos JA; Blazing MA; van Es GA; Kayikçioglu M; Arntz HR; den Hartog FR; Veeger NJ; Colivicchi F; Dupuis J; Okazaki S; Wright RS; Bucher HC; Nordmann AJ. JAMA. 2006.

Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: a systematic review and collaborative meta-analysis of randomized trials

Briel, M.; Schwartz, G. G.; Bucher, H. C.; Nordmann, A. J.. European heart journal. 2006.

Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials.

Nordmann AJ; Nordmann A; Briel M; Keller U; Yancy WS Jr; Brehm BJ; Bucher HC. Archives of internal medicine. 2006.

Lack of efficacy and cost-effectiveness of drug-eluting stents: reply

Nordmann, Alain J.; Briel, Matthias; Bucher, Heiner C.. European heart journal. 2006.

Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis.

Nordmann AJ; Briel M; Bucher HC. European heart journal. 2006.

Prevalence and influence of diagnostic tests for acute respiratory tract infections in primary care.

Briel M; Young J; Tschudi P; Hersberger KE; Hugenschmidt C; Langewitz W; Bucher HC. Swiss Medical Weekly. 2006.

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection: a meta-analysis of randomised controlled trials.

Briel M; Boscacci R; Furrer H; Bucher HC. BMC Infectious Diseases. 2005.

Effect of different antilipidemic agents and diets on mortality: a systematic review.

Studer M; Briel M; Leimenstoll B; Glass TR; Bucher HC. Archives of internal medicine. 2005.

Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671].

Briel M; Christ-Crain M; Young J; Schuetz P; Huber P; Périat P; Bucher HC; Müller B. BMC family practice. 2005.

Randomized trials stopped early for benefit: a systematic review.

Montori VM; Devereaux PJ; Adhikari NK; Burns KE; Eggert CH; Briel M; Lacchetti C; Leung TW; Darling E; Bryant DM; Bucher HC; Schünemann HJ; Meade MO; Cook DJ; Erwin PJ; Sood A; Sood R; Lo B; Thompson CA; Zhou Q; Mills E; Guyatt GH. JAMA. 2005.

Statin therapy for prevention and treatment of acute and chronic cardiovascular disease: update on recent trials and metaanalyses.

Briel M; Nordmann AJ; Bucher HC. CURRENT OPINION IN LIPIDOLOGY. 2005.

Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials.

Briel M; Studer M; Glass TR; Bucher HC. The American journal of medicine. 2004.

Cystic fibrosis and CFTR.

Greger R; Schreiber R; Mall M; Wissner A; Hopf A; Briel M; Bleich M; Warth R; Kunzelmann K. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2001.

Cl- transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na+ channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC.

Briel M; Greger R; Kunzelmann K. The Journal of physiology. 1998.

No evidence for direct activation of the cystic fibrosis transmembrane conductance regulator by 8-cyclopentyl-1,3-dipropylxanthine.

Kunzelmann K; Briel M; Schreiber R; Ricken S; Nitschke R; Greger R. Cellular Physiology and Biochemistry. 1998.

KVLQT channels are inhibited by the K+ channel blocker 293B.

Bleich M; Briel M; Busch AE; Lang HJ; Gerlach U; Gögelein H; Greger R; Kunzelmann K. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 1997.

The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca2+ activated Cl- conductance of Xenopus oocytes.

Kunzelmann K; Mall M; Briel M; Hipper A; Nitschke R; Ricken S; Greger R. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 1997.