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Klinische Forschung
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Publications Schmid Yasmin

A non-hallucinogenic LSD analog with therapeutic potential for mood disorders.

Lewis V; Bonniwell EM; Lanham JK; Ghaffari A; Sheshbaradaran H; Cao AB; Calkins MM; Bautista-Carro MA; Arsenault E; Telfer A; Taghavi-Abkuh FF; Malcolm NJ; El Sayegh F; Abizaid A; Schmid Y; Morton K; Halberstadt AL; Aguilar-Valles A; McCorvy JD. Cell Reports. 2023.

Krampfanfall nach schwerer Asthmaexazerbation

Stucky S; Müller O; Schmid Y; Leuppi-Taegtmeyer A. . 2023.

Severity of emergency department presentations due to acute drug toxicity in Europe: a longitudinal analysis over a 6-year period (2014-2019) stratified by sex.

Miró Ò; Burillo-Putze G; Schmid Y; Salgado E; Liechti ME; Dines AM; Giraudon I; Heyerdahl F; Hovda KE; Vallersne OM; Eyer F; Wood DM; Yates C; Dargan PI; Galicia M; Euro-DEN Plus Research Group. European journal of emergency medicine : official journal of the European Society for Emergency Medicine. 2023.

Age- and sex-related differences in clinical presentations due to acute cannabis toxicity at European Emergency Departments

Schmid Y; Galicia M; Vogt SB; Liechti ME; Burillo-Putze G; Dargan PI; Dines A; Giraudon I; Heyerdahl F; Hovda KE; Wood DM; Yates C; Miró O. . 2022.

Clinical effect of ethanol co-use in patients with acute drug toxicity involving the use of central nervous system depressant recreational drugs.

Heier EC; Eyer F; Rabe C; Geith S; Dargan PI; Wood DM; Heyerdahl F; Dines AM; Giraudon I; Erik Hovda K; Yates C; Vallersnes OM; Miró Ò; Liechti ME; Zellner T; Euro-DEN Research Group.. European journal of emergency medicine : official journal of the European Society for Emergency Medicine. 2022.

Differences in clinical features associated with cannabis intoxication in presentations to European emergency departments according to patient age and sex.

Schmid Y; Galicia M; Vogt SB; Liechti ME; Burillo-Putze G; Dargan PI; Dines AM; Giraudon I; Heyerdahl F; Hovda KE; Wood DM; Yates C; Miró Ò; (on behalf of the Euro-DEN Plus Research Group). Clinical Toxicology. 2022.

Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants

Muller F.; Kraus E.; Holze F.; Becker A.; Ley L.; Schmid Y.; Vizeli P.; Liechti M.E.; Borgwardt S.. Psychopharmacology. 2022.

Gastrointestinal bleeding during anticoagulation with direct oral anticoagulants compared to vitamin K antagonists.

Dongre K; Schmid Y; Nussbaum L; Winterhalder C; Bassetti S; Holbro A; Degen L; Leuppi-Taegtmeyer AB. Global cardiology science & practice. 2022.

Investigation of the Pharmacological Properties of 2-Br-LSD, a Non-Hallucinogenic LSD Analog

Halberstadt A; Schmid Y; Bonniwell E; Lanham J; Ghaffari A; Coo A; Sheshbaradaran H; McCorvy J. . 2022.

Acute subjective effects in LSD- and MDMA-assisted psychotherapy.

Schmid Y; Gasser P; Oehen P; Liechti ME. Journal of psychopharmacology (Oxford, England). 2021.

Acute toxicity related to misuse (nonmedical use) of tramadol: Experience of the European Drug Emergencies Network Plus.

Layne KA; Dargan PI; Dines AM; Leaper C; Yates C; Hovda KE; Heyerdahl F; Archer JRH; Giraudon I; Wood DM; Euro-DEN Plus Research Group.. British Journal of Clinical Pharmacology. 2021.

Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis.

Vizeli P; Straumann I; Holze F; Schmid Y; Dolder PC; Liechti ME. Scientific Reports. 2021.

MDMA-related presentations to the emergency departments of the European Drug Emergencies Network plus (Euro-DEN Plus) over the four-year period 2014-2017.

Noseda R; Schmid Y; Scholz I; Liakoni E; Liechti ME; Dargan PI; Wood DM; Dines AM; Yates C; Heyerdahl F; Hovda KE; Giraudon I; Ceschi A; Euro-DEN Research Group. Clinical Toxicology. 2021.

SOP Paracetamolintoxikation

Istampoulouoglou I; Schmid Y. . 2021.

Emergency department presentations related to acute toxicity following recreational use of cannabis products in Switzerland.

Schmid Y; Scholz I; Mueller L; Exadaktylos AK; Ceschi A; Liechti ME; Liakoni E. Drug and alcohol dependence. 2020.

Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults.

Suenderhauf C; Berger B; Puchkov M; Schmid Y; Müller S; Huwyler J; Haschke M; Krähenbühl S; Duthaler U. British Journal of Clinical Pharmacology. 2020.

Psychedelika in der Behandlung von Cluster-Kopfschmerzen

Schmid Y. . 2020.

[Knockout Drugs: Diagnostics in the Emergency Unit and Clinical Practice].

Bühler T; Schmid Y; Liechti ME. Praxis. 2019.

Emergency department presentations related to abuse of prescription and over-the-counter drugs in Switzerland: time trends, sex and age distribution.

Scholz I; Schmid Y; Exadaktylos AK; Haschke M; Liechti ME; Liakoni E. Swiss medical weekly. 2019.

Hypersensitivity reaction with multi-organ failure following re-exposure to rifampicin: case report and review of the literature including WHO spontaneous safety reports.

Brockhaus L; Schmid Y; Rast AC; Rätz Bravo AE; Hofmeier KS; Leuppi-Taegtmeyer AB. BMC pharmacology & toxicology. 2019.

Microdosed midazolam for the determination of cytochrome P450 3A activity: Development and clinical evaluation of a buccal film.

Kiene K; Hayasi N; Burhenne J; Uchitomi R; Sünderhauf C; Schmid Y; Haschke M; Haefeli WE; Krähenbühl S; Mikus G; Inada H; Huwyler J. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2019.

Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions.

Leuppi-Taegtmeyer A; Duthaler U; Hammann F; Schmid Y; Dickenmann M; Amico P; Jehle AW; Kalbermatter S; Lenherr C; Meyer Zu Schwabedissen HE; Haschke M; Liechti ME; Krähenbühl S. Nephrology Dialysis Transplantation. 2019.

Seizures as a complication of recreational drug use: Analysis of the Euro-DEN Plus data-set.

Wolfe CE; Wood DM; Dines A; Whatley BP; Yates C; Heyerdahl F; Hovda KE; Giraudon I; Dargan PI; Euro-DEN Research Group.. Neurotoxicology. 2019.

Sex differences in the pharmacology of itch therapies-a narrative review.

Schmid Y; Navarini A; Thomas ZM; Pfleiderer B; Krähenbühl S; Mueller SM. Current opinion in pharmacology. 2019.

Acute Effects of Methylphenidate, Modafinil, and MDMA on Negative Emotion Processing.

Schmidt A; Müller F; Dolder PC; Schmid Y; Zanchi D; Egloff L; Liechti ME; Borgwardt S. The international journal of neuropsychopharmacology. 2018.

Acute LSD effects on response inhibition neural networks

Schmidt A.; Muller F.; Lenz C.; Dolder P.C.; Schmid Y.; Zanchi D.; Lang U.E.; Liechti M.E.; Borgwardt S.. Psychological medicine. 2018.

Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects.

Dolder PC; Müller F; Schmid Y; Borgwardt SJ; Liechti ME. Psychopharmacology. 2018.

Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes.

Boxler MI; Streun GL; Liechti ME; Schmid Y; Kraemer T; Steuer AE. Journal of Proteome Research. 2018.

Long-lasting subjective effects of LSD in normal subjects.

Schmid Y; Liechti ME. Psychopharmacology. 2018.

Acute effects of LSD on amygdala activity during processing of fearful stimuli in healthy subjects

Mueller F.; Lenz C.; Dolder P.C.; Harder S.; Schmid Y.; Lang U.E.; Liechti M.E.; Borgwardt S.. Translational Psychiatry. 2017.

Alcohol acutely enhances decoding of positive emotions and emotional concern for positive stimuli and facilitates the viewing of sexual images

Dolder P.C.; Holze F.; Liakoni E.; Harder S.; Schmid Y.; Liechti M.E.. Psychopharmacology. 2017.

Alterations of consciousness and mystical-type experiences after acute LSD in humans.

Liechti ME; Dolder PC; Schmid Y. Psychopharmacology. 2017.

Comparative Effects of Methylphenidate, Modafinil, and MDMA on Response Inhibition Neural Networks in Healthy Subjects.

Schmidt A; Müller F; Dolder PC; Schmid Y; Zanchi D; Liechti ME; Borgwardt S. The international journal of neuropsychopharmacology. 2017.

Development and validation of an ultra-fast and sensitive microflow liquid chromatography-tandem mass spectrometry (MFLC-MS/MS) method for quantification of LSD and its metabolites in plasma and application to a controlled LSD administration study in humans.

Steuer AE; Poetzsch M; Stock L; Eisenbeiss L; Schmid Y; Liechti ME; Kraemer T. Drug Testing and Analysis. 2017.

First Time View on Human Metabolome Changes after a Single Intake of 3,4-Methylenedioxymethamphetamine in Healthy Placebo-Controlled Subjects.

Boxler MI; Liechti ME; Schmid Y; Kraemer T; Steuer AE. Journal of Proteome Research. 2017.

Pharmacogenetics of 3,4-methylenedioxymethamphetamine (MDMA): cytochrome P450 polymorphisms moderate pharmacokinetics and pharmacodynamic effects of MDMA in healthy subjects.

Vizeli P; Schmid Y; Liechti ME. . 2017.

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects.

Vizeli P; Schmid Y; Prestin K; Meyer Zu Schwabedissen HE; Liechti ME. European Neuropsychopharmacology. 2017.

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects.

Dolder PC; Schmid Y; Steuer AE; Kraemer T; Rentsch KM; Hammann F; Liechti ME. Clinical Pharmacokinetics. 2017.

Pharmacokinetics and pharmacodynamics of two doses of oral LSD in healthy subjects.

Liechti ME; Schmid Y; Rentsch KM; Hammann F; Dolder PC. . 2017.

Acute dose-response of LSD in healthy subjects

Dolder PC; Schmid Y; Borgwardt SJ; Rentsch KM; Liechti ME. . 2016.

Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects

Strajhar P.; Schmid Y.; Liakoni E.; Dolder P.C.; Rentsch K.M.; Kratschmar D.V.; Odermatt A.; Liechti M.E.. Journal of Neuroendocrinology. 2016.

CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of MDMA in a controlled study in healthy subjects

Schmid Y; Vizeli P; Hysek CM; Prestin K; Meyer zu Schwabedissen HE; Liechti ME. . 2016.

Cytochrome 2D6 function moderates the pharmacokinetics and pharmacodynamics of MDMA in healthy subjects

Schmid, Y.; Vizeli, P.; Hysek, C.; Prestin, K.; zu Schwabedissen, H. Meyer; Liechti, M.. European Neuropsychopharmacology. 2016.

Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans.

Steuer AE; Schmidhauser C; Tingelhoff EH; Schmid Y; Rickli A; Kraemer T; Liechti ME. PLoS ONE. 2016.

LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality.

Dolder PC; Schmid Y; Müller F; Borgwardt S; Liechti ME. Neuropsychopharmacology. 2016.

Pharmacokinetics and concentration-effect relationship of oral LSD in humans

Dolder P.C.; Schmid Y.; Haschke M.; Rentsch K.M.; Liechti M.E.. The international journal of neuropsychopharmacology. 2016.

Acute autonomic and psychotropic effects of LSD in healthy subject in a placebo-controlled study

Schmid Y; Dolder PC; Liechti ME. . 2015.

Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects.

Schmid Y; Enzler F; Gasser P; Grouzmann E; Preller KH; Vollenweider FX; Brenneisen R; Müller F; Borgwardt S; Liechti ME. Biological psychiatry. 2015.

Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans.

Steuer AE; Schmidhauser C; Schmid Y; Rickli A; Liechti ME; Kraemer T. Drug Metabolism and Disposition. 2015.

Effects of methylphenidate and MDMA on appraisal of erotic stimuli and intimate relationships.

Schmid Y; Hysek CM; Preller KH; Bosch OG; Bilderbeck AC; Rogers RD; Quednow BB; Liechti ME. European Neuropsychopharmacology. 2015.

Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects.

Schmid Y; Rickli A; Schaffner A; Duthaler U; Grouzmann E; Hysek CM; Liechti ME. The Journal of pharmacology and experimental therapeutics. 2015.

Pharmacology of LSD in humans.

Dolder PC; Schmid Y; Rentsch K; Liechti ME. . 2015.

Acute effects of 3,4-methylenedioxymethamphetamine and methylphenidate on circulating steroid levels in healthy subjects.

Seibert J; Hysek CM; Penno CA; Schmid Y; Kratschmar DV; Liechti ME; Odermatt A. Neuroendocrinology. 2014.

Acute effects of methylphenidate in healthy subjects alone and in combination with MDMA

Schmid Y; Hysek CM; Liechti ME. . 2014.

Differential effects of MDMA and methylphenidate on social cognition.

Schmid Y; Hysek CM; Simmler LD; Crockett MJ; Quednow BB; Liechti ME. Journal of psychopharmacology (Oxford, England). 2014.

Effects of methylphenidate and MDMA (ecstasy) on appraisal of erotic stimuli

Schmid Y; Quednow BB; Liechti ME. . 2014.

MDMA enhances emotional empathy and prosocial behavior.

Hysek CM; Schmid Y; Simmler LD; Domes G; Heinrichs M; Eisenegger C; Preller KH; Quednow BB; Liechti ME. Social cognitive and affective neuroscience. 2014.

Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination.

Hysek CM; Simmler LD; Schillinger N; Meyer N; Schmid Y; Donzelli M; Grouzmann E; Liechti ME. The international journal of neuropsychopharmacology. 2014.

Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans: Lost in translation

Hysek C.M.; Schmid Y.; Rickli A.; Liechti M.E.. British Journal of Pharmacology. 2013.

Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans.

Hysek C; Schmid Y; Rickli A; Simmler LD; Donzelli M; Grouzmann E; Liechti ME. British Journal of Pharmacology. 2012.