A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients.

Todea AR; Melie-Garcia L; Barakovic M; Cagol A; Rahmanzadeh R; Galbusera R; Lu PJ; Weigel M; Ruberte E; Radue EW; Schaedelin S; Benkert P; Oezguer Y; Sinnecker T; Müller S; Achtnichts L; Vehoff J; Disanto G; Findling O; Chan A; Salmen A; Pot C; Lalive P; Bridel C; Zecca C; Derfuss T; Remonda L; Wagner F; Vargas M; Du Pasquier R; Pravata E; Weber J; Gobbi C; Leppert D; Wuerfel J; Kober T; Marechal B; Corredor-Jerez R; Psychogios M; Lieb J; Kappos L; Cuadra MB; Kuhle J; Granziera C; Swiss MS Cohort Study. Journal of magnetic resonance imaging : JMRI. 2023.

An investigation of the association between focal damage and global network properties in cognitively impaired and cognitively preserved patients with multiple sclerosis.

Wenger AL; Barakovic M; Bosticardo S; Schaedelin S; Daducci A; Schiavi S; Weigel M; Rahmanzadeh R; Lu PJ; Cagol A; Kappos L; Kuhle J; Calabrese P; Granziera C. Frontiers in neuroscience. 2023.

Anterior horn atrophy in the cervical spinal cord: A new biomarker in progressive multiple sclerosis.

Tsagkas C; Huck-Horvath A; Cagol A; Haas T; Barakovic M; Amann M; Ruberte E; Melie-Garcia L; Weigel M; Pezold S; Schlaeger R; Kuhle J; Sprenger T; Kappos L; Bieri O; Cattin P; Granziera C; Parmar K. Multiple sclerosis (Houndmills, Basingstoke, England). 2023.

Fully Automatic Method for Reliable Spinal Cord Compartment Segmentation in Multiple Sclerosis

Tsagkas C.; Horvath-Huck A.; Haas T.; Amann M.; Todea A.; Altermatt A.; Muller J.; Cagol A.; Leimbacher M.; Barakovic M.; Weigel M.; Pezold S.; Sprenger T.; Kappos L.; Bieri O.; Granziera C.; Cattin P.; Parmar K.. AJNR. American journal of neuroradiology. 2023.

Hemiparkinsonism caused by a lateral sphenoid wing meningioma, with tractography analysis: illustrative case.

Saemann A; Busch S; Taub E; Westermann B; Granziera C; Guzman R; Mariani L; Soleman J; Rychen J. Journal of neurosurgery. Case lessons. 2023.

Longitudinal assessment of cervical spinal cord compartments in multiple sclerosis.

Tsagkas C; Huck-Horvath A; Cagol A; Haas T; Amann M; Barakovic M; Ruberte E; Melie-Garcia L; Weigel M; Pezold S; Schlaeger R; Kuhle J; Sprenger T; Kappos L; Bieri O; Cattin P; Granziera C; Parmar K. Multiple sclerosis and related disorders. 2023.

One for all, all for one: neuro-HIV multidisciplinary platform for the assessment and management of neurocognitive complaints in people living with HIV.

Damas J; Darling KEA; Bidlingmeyer P; Nadin-Debluë I; Bieler M; Vollino L; Sokolov AA; Berney A; Maccaferri G; Filippidis P; Viala B; Granziera C; Dunet V; Du Pasquier R; Cavassini M. HIV medicine. 2023.

Optical coherence tomography reflects clinically relevant gray matter damage in patients with multiple sclerosis.

Cagol A; Fuertes NC; Stoessel M; Barakovic M; Schaedelin S; D'Souza M; Würfel J; Brandt AU; Kappos L; Sprenger T; Naegelin Y; Kuhle J; Granziera C; Papadopoulou A. Journal of neurology. 2023.

Personalized maps of T1 relaxometry abnormalities provide correlates of disability in multiple sclerosis patients.

Chen X; Schädelin S; Lu PJ; Ocampo-Pineda M; Weigel M; Barakovic M; Ruberte E; Cagol A; Marechal B; Kober T; Kuhle J; Kappos L; Melie-Garcia L; Granziera C. NeuroImage. Clinical. 2023.

Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis.

Meier S; Willemse EAJ; Schaedelin S; Oechtering J; Lorscheider J; Melie-Garcia L; Cagol A; Barakovic M; Galbusera R; Subramaniam S; Barro C; Abdelhak A; Thebault S; Achtnichts L; Lalive P; Müller S; Pot C; Salmen A; Disanto G; Zecca C; D'Souza M; Orleth A; Khalil M; Buchmann A; Du Pasquier R; Yaldizli Ö; Derfuss T; Berger K; Hermesdorf M; Wiendl H; Piehl F; Battaglini M; Fischer U; Kappos L; Gobbi C; Granziera C; Bridel C; Leppert D; Maleska Maceski A; Benkert P; Kuhle J. JAMA neurology. 2023.

Time to Change the Current Clinical Classification of Multiple Sclerosis?

Granziera C; Derfuss T; Kappos L. JAMA neurology. 2023.

Understanding the Role of the Choroid Plexus in Multiple Sclerosis as an MRI Biomarker of Disease Activity.

Müller J; Noteboom S; Granziera C; Schoonheim MM. . 2023.

A comparative assessment of myelin-sensitive measures in multiple sclerosis patients and healthy subjects.

Rahmanzadeh R; Weigel M; Lu PJ; Melie-Garcia L; Nguyen TD; Cagol A; La Rosa F; Barakovic M; Lutti A; Wang Y; Bach Cuadra M; Radue EW; Gaetano L; Kappos L; Kuhle J; Magon S; Granziera C. NeuroImage. Clinical. 2022.

A New Advanced MRI Biomarker for Remyelinated Lesions in Multiple Sclerosis.

Rahmanzadeh R; Galbusera R; Lu PJ; Bahn E; Weigel M; Barakovic M; Franz J; Nguyen TD; Spincemaille P; Schiavi S; Daducci A; La Rosa F; Absinta M; Sati P; Bach Cuadra M; Radue EW; Leppert D; Kuhle J; Kappos L; Brück W; Reich DS; Stadelmann C; Wang Y; Granziera C. Annals of neurology. 2022.

Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis.

Cagol A; Schaedelin S; Barakovic M; Benkert P; Todea RA; Rahmanzadeh R; Galbusera R; Lu PJ; Weigel M; Melie-Garcia L; Ruberte E; Siebenborn N; Battaglini M; Radue EW; Yaldizli Ö; Oechtering J; Sinnecker T; Lorscheider J; Fischer-Barnicol B; Müller S; Achtnichts L; Vehoff J; Disanto G; Findling O; Chan A; Salmen A; Pot C; Bridel C; Zecca C; Derfuss T; Lieb JM; Remonda L; Wagner F; Vargas MI; Du Pasquier R; Lalive PH; Pravatà E; Weber J; Cattin PC; Gobbi C; Leppert D; Kappos L; Kuhle J; Granziera C. JAMA neurology. 2022.

Brain atrophy measurement over a MRI scanner change in multiple sclerosis.

Sinnecker T; Schädelin S; Benkert P; Ruberte E; Amann M; Lieb JM; Naegelin Y; Müller J; Kuhle J; Derfuss T; Kappos L; Wuerfel J; Granziera C; Yaldizli Ö. NeuroImage. Clinical. 2022.

Brain cortical alterations in COVID-19 patients with neurological symptoms.

Sanabria-Diaz G; Etter MM; Melie-Garcia L; Lieb JM; Psychogios MN; Hutter G; Granziera C. Frontiers in neuroscience. 2022.

Bundle myelin fraction (BMF) mapping of different white matter connections using microstructure informed tractography.

Schiavi S; Lu PJ; Weigel M; Lutti A; Jones DK; Kappos L; Granziera C; Daducci A. NeuroImage. 2022.

Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder: A Retrospective, Cross-sectional Analysis.

Müller J; Sinnecker T; Wendebourg MJ; Schläger R; Kuhle J; Schädelin S; Benkert P; Derfuss T; Cattin P; Jud C; Spiess F; Amann M; Lincke T; Barakovic M; Cagol A; Tsagkas C; Parmar K; Pröbstel AK; Reimann S; Asseyer S; Duchow A; Brandt A; Ruprecht K; Hadjikhani N; Fukumoto S; Watanabe M; Masaki K; Matsushita T; Isobe N; Kira JI; Kappos L; Würfel J; Granziera C; Paul F; Yaldizli Ö. Neurology(R) neuroimmunology & neuroinflammation. 2022.

Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues.

La Rosa F; Wynen M; Al-Louzi O; Beck ES; Huelnhagen T; Maggi P; Thiran JP; Kober T; Shinohara RT; Sati P; Reich DS; Granziera C; Absinta M; Bach Cuadra M. NeuroImage. Clinical. 2022.

CSF chitinase 3-like 1 is associated with iron rims in patients with a first demyelinating event.

Comabella M; Clarke MA; Schaedelin S; Tintoré M; Pareto D; Fissolo N; Pinteac R; Granziera C; Sastre-Garriga J; Benkert P; Auger C; Kuhle J; Montalban X; Rovira A. Multiple sclerosis (Houndmills, Basingstoke, England). 2022.

Development and implementation of new diagnostic technologies in neurology.

Granziera C; Woelfle T; Kappos L. Nature reviews. Neurology. 2022.

Fluid and White Matter Suppression: New Sensitive 3 T Magnetic Resonance Imaging Contrasts for Cortical Lesion Detection in Multiple Sclerosis.

Müller J; La Rosa F; Beaumont J; Tsagkas C; Rahmanzadeh R; Weigel M; Bach Cuadra M; Gambarota G; Granziera C. Investigative radiology. 2022.

Incorporating outlier information into diffusion-weighted MRI modeling for robust microstructural imaging and structural brain connectivity analyses.

Sairanen V; Ocampo-Pineda M; Granziera C; Schiavi S; Daducci A. NeuroImage. 2022.

Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS.

Oechtering J; Lincke T; Schaedelin S; Décard BF; Maceski A; Orleth A; Meier S; Willemse E; Buchmann A; Khalil M; Derfuss T; Benkert P; Heijnen I; Regeniter A; Müller S; Achtnichts L; Lalive P; Salmen A; Pot C; Gobbi C; Kappos L; Granziera C; Leppert D; Schlaeger R; Lieb JM; Kuhle J; Swiss MS Cohort Study. Annals of neurology. 2022.

Learn to Ignore: Domain Adaptation for Multi-site MRI Analysis

Wolleb J.; Sandkuhler R.; Bieder F.; Barakovic M.; Hadjikhani N.; Papadopoulou A.; Yaldizli O.; Kuhle J.; Granziera C.; Cattin P.C.. . 2022.

Longitudinal changes of deep gray matter shape in multiple sclerosis.

Tsagkas C; Geiter E; Gaetano L; Naegelin Y; Amann M; Parmar K; Papadopoulou A; Wuerfel J; Kappos L; Sprenger T; Granziera C; Mallar Chakravarty M; Magon S. NeuroImage. Clinical. 2022.

Microstructure-Weighted Connectomics in Multiple Sclerosis.

Bosticardo S; Schiavi S; Schaedelin S; Lu PJ; Barakovic M; Weigel M; Kappos L; Kuhle J; Daducci A; Granziera C. Brain connectivity. 2022.

Multimodal Investigation of Neuroinflammation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers.

Sari H; Galbusera R; Bonnier G; Lin Y; Alshelh Z; Torrado-Carvajal A; Mukerji SS; Ratai EM; Gandhi RT; Chu JT; Akeju O; Orhurhu V; Salvatore AN; Sherman J; Kwon DS; Walker B; Rosen B; Price JC; Pollak LE; Loggia ML; Granziera C. Neurology(R) neuroimmunology & neuroinflammation. 2022.

Multiple sclerosis cortical lesion detection with deep learning at ultra-high-field MRI.

La Rosa F; Beck ES; Maranzano J; Todea RA; van Gelderen P; de Zwart JA; Luciano NJ; Duyn JH; Thiran JP; Granziera C; Reich DS; Sati P; Bach Cuadra M. NMR in Biomedicine. 2022.

Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis.

Meaton I; Altokhis A; Allen CM; Clarke MA; Sinnecker T; Meier D; Enzinger C; Calabrese M; De Stefano N; Pitiot A; Giorgio A; Schoonheim MM; Paul F; Pawlak MA; Schmidt R; Granziera C; Kappos L; Montalban X; Rovira À; Wuerfel J; Evangelou N. Multiple sclerosis (Houndmills, Basingstoke, England). 2022.

Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis.

Galbusera R; Bahn E; Weigel M; Schaedelin S; Franz J; Lu PJ; Barakovic M; Melie-Garcia L; Dechent P; Lutti A; Sati P; Reich DS; Nair G; Brück W; Kappos L; Stadelmann C; Granziera C. Brain pathology (Zurich, Switzerland). 2022.

Regional Cerebellar Volume Loss Predicts Future Disability in Multiple Sclerosis Patients.

Parmar K; Fonov VS; Naegelin Y; Amann M; Wuerfel J; Collins DL; Gaetano L; Magon S; Sprenger T; Kappos L; Granziera C; Tsagkas C. Cerebellum (London, England). 2022.

Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study.

Benkert P; Meier S; Schaedelin S; Manouchehrinia A; Yaldizli Ö; Maceski A; Oechtering J; Achtnichts L; Conen D; Derfuss T; Lalive PH; Mueller C; Müller S; Naegelin Y; Oksenberg JR; Pot C; Salmen A; Willemse E; Kockum I; Blennow K; Zetterberg H; Gobbi C; Kappos L; Wiendl H; Berger K; Sormani MP; Granziera C; Piehl F; Leppert D; Kuhle J; NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group. The Lancet. Neurology. 2022.

Serum NfL levels in the first five years predict 10-year thalamic fraction in patients with MS

Lokhande H.; Rosso M.; Tauhid S.; Chu R.; Healy B.C.; Saxena S.; Barro C.; Paul A.; Polgar-Turcsanyi M.; Anderson M.; Glanz B.I.; Kropshofer H.; Granziera C.; Leppert D.; Kappos L.; Kuhle J.; Weiner H.L.; Bakshi R.; Chitnis T.. Multiple sclerosis journal - experimental, translational and clinical. 2022.

Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study

Etter M.M.; Martins T.A.; Kulsvehagen L.; Possnecker E.; Duchemin W.; Hogan S.; Sanabria-Diaz G.; Muller J.; Chiappini A.; Rychen J.; Eberhard N.; Guzman R.; Mariani L.; Melie-Garcia L.; Keller E.; Jelcic I.; Pargger H.; Siegemund M.; Kuhle J.; Oechtering J.; Eich C.; Tzankov A.; Matter M.S.; Uzun S.; Yaldizli O.; Lieb J.M.; Psychogios M.-N.; Leuzinger K.; Hirsch H.H.; Granziera C.; Probstel A.-K.; Hutter G.. Nature Communications. 2022.

Smouldering multiple sclerosis: the 'real MS'.

Giovannoni G; Popescu V; Wuerfel J; Hellwig K; Iacobaeus E; Jensen MB; García-Domínguez JM; Sousa L; De Rossi N; Hupperts R; Fenu G; Bodini B; Kuusisto HM; Stankoff B; Lycke J; Airas L; Granziera C; Scalfari A. Therapeutic advances in neurological disorders. 2022.

Spinal cord gray matter atrophy is associated with functional decline in post-polio syndrome

Wendebourg M.J.; Weigel M.; Richter L.; Gocheva V.; Hafner P.; Orsini A.-L.; Crepulja V.; Schmidt S.; Huck A.; Oechtering J.; Blatow M.; Haas T.; Granziera C.; Kappos L.; Cattin P.; Bieri O.; Fischer D.; Schlaeger R.. European journal of neurology. 2022.

Alcohol consumption and neurocognitive deficits in people with well-treated HIV in Switzerland

Darling K.E.A.; Locatelli I.; Benghalem N.; Nadin I.; Calmy A.; Gutbrod K.; Hauser C.; Brugger P.; Hasse B.; Kovari H.; Kunze U.; Stoeckle M.; Fux C.; Rossi S.; Di Benedetto C.; Fruh S.; Schmid P.; Tarr P.E.; Daeppen J.-B.; Pasquier R.D.; Cavassini M.; Metral M.; Simioni S.; Monsch A.U.; Schneitter M.; Schwind M.; Pignatti R.; Clarke S.; Assal F.; Derfuss T.; von Arx S.; Jelcic I.; Sacco L.; Bertschi M.; Hundsberger T.; Lecompte T.D.; Cusini A.; Bernasconi E.; Bruno A.; Scherrer A.; Vallet Y.; Alves D.; Decosterd L.; Granziera C.; Krueger G.; Meuli R.; Vargas M.; Aebi-Popp K.; Anagnostopoulos A.; Battegay M.; Boni J.; Braun D.L.; Bucher H.C.; Ciuffi A.; Dollenmaier G.; Egger M.; Elzi L.; Fehr J.; Fellay J.; Furrer H.; Gunthard H.F.; Haerry D.; Hirsch H.H.; Hoffmann M.; Hosli I.; Huber M.; Kahlert C.R.; Kaiser L.; Keiser O.; Klimkait T.; Kouyos R.D.; Ledergerber B.; Martinetti G.; Martinez de Tejada B.; Marzolini C.; Metzner K.J.; Muller N.; Nicca D.; Paioni P.; Pantaleo G.; Perreau M.; Rauch A.; Rudin C.; Speck R.; Stockle M.; Trkola A.; Vernazza P.; Wandeler G.; Yerly S.. PLoS One. 2021.

A multimodal investigation of neuroinflammation in aviremic HIV patients on antiretroviral therapy and HIV elite controllers.

Sari H.; Galbusera R.; Bonnier G.; Lin Y.; Alshelh Z.; Torrado-Carvajal A.; Mukerji S.S.; Ratai EM; Gandhi R.T.; Chu JT; Akeju O; Orhurhu V.; Salvatore A.N.; Sherman J.; Kwon, D.S.; Walker B.; Rosen B.; Price J.C.; Pollak L.E.; Loggia M.; Granziera C.. . 2021.

Bundle-Specific Axon Diameter Index as a New Contrast to Differentiate White Matter Tracts.

Barakovic M; Girard G; Schiavi S; Romascano D; Descoteaux M; Granziera C; Jones DK; Innocenti GM; Thiran JP; Daducci A. Frontiers in neuroscience. 2021.

Central nervous system atrophy predicts future dynamics of disability progression in a real-world multiple sclerosis cohort.

Tsagkas C; Naegelin Y; Amann M; Papadopoulou A; Barro C; Chakravarty MM; Gaetano L; Wuerfel J; Kappos L; Kuhle J; Granziera C; Sprenger T; Magon S; Parmar K. European journal of neurology. 2021.

Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis.

Maggi P; Kuhle J; Schädelin S; van der Meer F; Weigel M; Galbusera R; Mathias A; Lu PJ; Rahmanzadeh R; Benkert P; La Rosa F; Bach Cuadra M; Sati P; Théaudin M; Pot C; van Pesch V; Leppert D; Stadelmann C; Kappos L; Du Pasquier R; Reich DS; Absinta M; Granziera C. Neurology. 2021.

Classification of multiple sclerosis based on patterns of CNS regional atrophy covariance.

Tsagkas C; Parmar K; Pezold S; Barro C; Chakravarty MM; Gaetano L; Naegelin Y; Amann M; Papadopoulou A; Wuerfel J; Kappos L; Kuhle J; Sprenger T; Granziera C; Magon S. Human brain mapping. 2021.

Enhancing reliability of structural brain connectivity with outlier adjusted tractogram filtering

Sairanen V.; Ocampo-Pineda M.; Granziera C.; Schiavi S.; Daducci A.. . 2021.

GAMER MRI: Gated-attention mechanism ranking of multi-contrast MRI in brain pathology.

Lu PJ; Yoo Y; Rahmanzadeh R; Galbusera R; Weigel M; Ceccaldi P; Nguyen TD; Spincemaille P; Wang Y; Daducci A; La Rosa F; Bach Cuadra M; Sandkühler R; Nael K; Doshi A; Fayad ZA; Kuhle J; Kappos L; Odry B; Cattin P; Gibson E; Granziera C. NeuroImage. Clinical. 2021.

GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation.

Lu PJ; Barakovic M; Weigel M; Rahmanzadeh R; Galbusera R; Schiavi S; Daducci A; La Rosa F; Bach Cuadra M; Sandkühler R; Kuhle J; Kappos L; Cattin P; Granziera C. Frontiers in neuroscience. 2021.

Imaging multiple sclerosis pathology at 160 μm isotropic resolution by human whole-brain ex vivo magnetic resonance imaging at 3 T

Weigel M.; Dechent P.; Galbusera R.; Bahn E.; Nair G.; Lu P.-J.; Kappos L.; Bruck W.; Stadelmann C.; Granziera C.. Scientific Reports. 2021.

Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis.

Oechtering J; Schaedelin S; Benkert P; Müller S; Achtnichts L; Vehoff J; Disanto G; Findling O; Fischer-Barnicol B; Orleth A; Chan A; Pot C; Barakovic M; Rahmanzadeh R; Galbusera R; Heijnen I; Lalive PH; Wuerfel J; Subramaniam S; Aeschbacher S; Conen D; Naegelin Y; Maceski A; Meier S; Berger K; Wiendl H; Lincke T; Lieb J; Yaldizli Ö; Sinnecker T; Derfuss T; Regeniter A; Zecca C; Gobbi C; Kappos L; Granziera C; Leppert D; Kuhle J; Swiss Multiple Sclerosis Cohort Study. Annals of neurology. 2021.

Model-informed machine learning for multi-component T(2) relaxometry.

Yu T; Canales-Rodríguez EJ; Pizzolato M; Piredda GF; Hilbert T; Fischi-Gomez E; Weigel M; Barakovic M; Bach Cuadra M; Granziera C; Kober T; Thiran JP. MEDICAL IMAGE ANALYSIS. 2021.

MPRAGE to MP2RAGE UNI translation via generative adversarial network improves the automatic tissue and lesion segmentation in multiple sclerosis patients.

La Rosa F; Yu T; Barquero G; Thiran JP; Granziera C; Bach Cuadra M. Computers in Biology and Medicine. 2021.

Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging.

Rahmanzadeh R; Lu PJ; Barakovic M; Weigel M; Maggi P; Nguyen TD; Schiavi S; Daducci A; La Rosa F; Schaedelin S; Absinta M; Reich DS; Sati P; Wang Y; Bach Cuadra M; Radue EW; Kuhle J; Kappos L; Granziera C. Brain : a journal of neurology. 2021.

Normalization of Spinal Cord Total Cross-Sectional and Gray Matter Areas as Quantified With Radially Sampled Averaged Magnetization Inversion Recovery Acquisitions.

Kesenheimer EM; Wendebourg MJ; Weigel M; Weidensteiner C; Haas T; Richter L; Sander L; Horvath A; Barakovic M; Cattin P; Granziera C; Bieri O; Schlaeger R. Frontiers in neurology. 2021.

Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis

Granziera C.; Wuerfel J.; Barkhof F.; Calabrese M.; De Stefano N.; Enzinger C.; Evangelou N.; Filippi M.; Geurts J.J.G.; Reich D.S.; Rocca M.A.; Ropele S.; Rovira A.; Sati P.; Toosy A.T.; Vrenken H.; Gandini Wheeler-Kingshott C.A.M.; Kappos L.. Brain : a journal of neurology. 2021.

Resolving bundle-specific intra-axonal T(2) values within a voxel using diffusion-relaxation tract-based estimation.

Barakovic M; Tax CMW; Rudrapatna U; Chamberland M; Rafael-Patino J; Granziera C; Thiran JP; Daducci A; Canales-Rodríguez EJ; Jones DK. NeuroImage. 2021.

The association between depressive symptoms and neurocognitive impairment in people with well-treated HIV in Switzerland

Santos G.; Locatelli I.; Metral M.; Berney A.; Nadin I.; Calmy A.; Tarr P.; Gutbrod K.; Hauser C.; Brugger P.; Kovari H.; Kunze U.; Stoeckle M.; Fruh S.; Schmid P.; Rossi S.; Di Benedetto C.; Du Pasquier R.; Darling K.; Cavassini M.; Simioni S.; Monsch A.U.; Schneitter M.; Schwind M.; Pignatti R.; Clarke S.; Assal F.; Derfuss T.; von Arx S.; Eisele G.; Sacco L.; Bertschi M.; Hundsberger T.; Lecompte T.D.; Cusini A.; Weber R.; Hasse B.; Fux C.; Bernasconi E.; Scherrer A.; Vallet Y.; Alves D.; Decosterd L.; Granziera C.; Krueger G.; Meuli R.; Vargas M.; Aebi-Popp K.; Anagnostopoulos A.; Battegay M.; Boni J.; Braun D.L.; Bucher H.C.; Calmy A.; Cavassini M.; Ciuffi A.; Dollenmaier G.; Egger M.; Elzi L.; Fehr J.; Fellay J.; Furrer H.; Gunthard H.F.; Haerry D.; Hirsch H.H.; Hoffmann M.; Hosli I.; Huber M.; Kahlert C.R.; Kaiser L.; Keiser O.; Klimkait T.; Kouyos R.D.; Kovari H.; Ledergerber B.; Martinetti G.; de Tejada B.M.; Marzolini C.; Metzner K.J.; Muller N.; Nicca D.; Paioni P.; Pantaleo G.; Perreau M.; Rauch A.; Rudin C.; Schmid P.; Speck R.; Stockle M.; Trkola A.; Vernazza P.; Wandeler G.; Yerly S.. International Journal of STD and AIDS. 2021.

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?

Schilling K.G.; Rheault F.; Petit L.; Hansen C.B.; Nath V.; Yeh F.-C.; Girard G.; Barakovic M.; Rafael-Patino J.; Yu T.; Fischi-Gomez E.; Pizzolato M.; Ocampo-Pineda M.; Schiavi S.; Canales-Rodriguez E.J.; Daducci A.; Granziera C.; Innocenti G.; Thiran J.-P.; Mancini L.; Wastling S.; Cocozza S.; Petracca M.; Pontillo G.; Mancini M.; Vos S.B.; Vakharia V.N.; Duncan J.S.; Melero H.; Manzanedo L.; Sanz-Morales E.; Pena-Melian A.; Calamante F.; Attye A.; Cabeen R.P.; Korobova L.; Toga A.W.; Vijayakumari A.A.; Parker D.; Verma R.; Radwan A.; Sunaert S.; Emsell L.; De Luca A.; Leemans A.; Bajada C.J.; Haroon H.; Azadbakht H.; Chamberland M.; Genc S.; Tax C.M.W.; Yeh P.-H.; Srikanchana R.; Mcknight C.D.; Yang J.Y.-M.; Chen J.; Kelly C.E.; Yeh C.-H.; Cochereau J.; Maller J.J.; Welton T.; Almairac F.; Seunarine K.K.; Clark C.A.; Zhang F.; Makris N.; Golby A.; Rathi Y.; O'Donnell L.J.; Xia Y.; Aydogan D.B.; Shi Y.; Fernandes F.G.; Raemaekers M.; Warrington S.; Michielse S.; Ramirez-Manzanares A.; Concha L.; Aranda R.; Meraz M.R.; Lerma-Usabiaga G.; Roitman L.; Fekonja L.S.; Calarco N.; Joseph M.; Nakua H.; Voineskos A.N.; Karan P.; Grenier G.; Legarreta J.H.; Adluru N.; Nair V.A.; Prabhakaran V.; Alexander A.L.; Kamagata K.; Saito Y.; Uchida W.; Andica C.; Abe M.; Bayrak R.G.; Wheeler-Kingshott C.A.M.G.; D'Angelo E.; Palesi F.; Savini G.; Rolandi N.; Guevara P.; Houenou J.; Lopez-Lopez N.; Mangin J.-F.; Poupon C.; Roman C.; Vazquez A.; Maffei C.; Arantes M.; Andrade J.P.; Silva S.M.; Calhoun V.D.; Caverzasi E.; Sacco S.; Lauricella M.; Pestilli F.; Bullock D.; Zhan Y.; Brignoni-Perez E.; Lebel C.; Reynolds J.E.; Nestrasil I.; Labounek R.; Lenglet C.; Paulson A.; Aulicka S.; Heilbronner S.R.; Heuer K.; Chandio B.Q.; Guaje J.; Tang W.; Garyfallidis E.; Raja R.; Anderson A.W.; Landman B.A.; Descoteaux M.. NeuroImage. 2021.

Ultrahigh field in vivo characterization of microstructural abnormalities in the orbitofrontal cortex and amygdala in autism

Fischi-Gomez E.; Bonnier G.; Ward N.; Granziera C.; Hadjikhani N.. The European journal of neuroscience. 2021.

Brain Network Analyses in Clinical Neuroscience.

Sokolov, A. A.; Granziera C.; Fischi Gomez E., Pretig M.G.; Ryvlin P.; Van de Ville D.; Friston K.J. . 2020.

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis.

Maggi P; Fartaria MJ; Jorge J; La Rosa F; Absinta M; Sati P; Meuli R; Du Pasquier R; Reich DS; Cuadra MB; Granziera C; Richiardi J; Kober T. NMR in Biomedicine. 2020.

Evolution of Cortical and White Matter Lesion Load in Early-Stage Multiple Sclerosis: Correlation With Neuroaxonal Damage and Clinical Changes.

Todea RA; Lu PJ; Fartaria MJ; Bonnier G; Du Pasquier R; Krueger G; Bach Cuadra M; Psychogios MN; Kappos L; Kuhle J; Granziera C. Frontiers in neurology. 2020.

Extra-Axial Inflammatory Signal in Parameninges in Migraine with Visual Aura.

Hadjikhani N; Albrecht DS; Mainero C; Ichijo E; Ward N; Granziera C; Zürcher NR; Akeju O; Bonnier G; Price J; Hooker JM; Napadow V; Nahrendorf M; Loggia ML; Moskowitz MA. Annals of neurology. 2020.

Gadolinium should always be used to assess disease activity in MS - Yes.

Granziera C; Reich DS. Multiple sclerosis (Houndmills, Basingstoke, England). 2020.

How helpful are the European AIDS Clinical Society cognitive screening questions in predicting cognitive impairment in an aging, well-treated HIV-positive population?

Metral M.; Nadin I.; Locatelli; I.; Tarr P.E.; Calmy A.; Kovari H.; Brugger P.; Cusini A.; Gutbrod K.; Schmid P.; Schwind M.; Kunze U.; Di Benedetto C.; Pignatti R.; Du Pasquier R.; Darling K.E.A.; Cavassini M.; Cavassini M.; Pasquier R.D.; Metral M.; Simioni S.; Brugger P.; Gutbrod K.; Monsch A.U.; Kunze U.; Schneitter M.; Nadin I.; Fruh S.; Schwind M.; Pignatti R.; Clarke; S.; Assal F.; Derfuss T.; von Arx S.; Eisele G.; Sacco L.; Bertschi M.; Hundsberger T.; Pasquier R.D.; Calmy A.; Doco Lecompte T.; Hauser C.; Cusini A.; Weber R.; Kovari H.; Hasse B.; Stoeckle M.; Fux C.A.; Bernasconi E.; Di Benedetto C.; Bruno A.; Schmid P.; Darling K.; Cavassini M.; Scherrer A.; Scherrer A.; Vallet Y.; Alves D.; Locatelli; I.; Decosterd L.; Granziera C.; Krueger G.; Meuli R.; Vargas M.; Aebi-Popp K.; Anagnostopoulos A.; Battegay M.; Bernasconi E.; Boni J.; Braun D.L.; Bucher H.C.; Calmy A.; Cavassini M.; Ciuffi A.; Dollenmaier G.; Egger M.; Elzi L.; Fehr J.; Fellay J.; Furrer H.; Fux C.A.; Gunthard H.F.; Haerry D.; Hasse B.; Hirsch H.H.; Hoffmann M.; Hosli I.; Huber M.; Kahlert C.R.; Kaiser L.; Keiser O.; Klimkait T.; Kouyos R.D.; Kovari H.; Ledergerber B.; Martinetti G.; Martinez de Tejada B.; Marzolini C.; Metzner K.J.; Muller N.; Nicca D.; Paioni P.; Pantaleo G.; Perreau M.; Rauch A.; Rudin C.; Scherrer A.U.; Schmid P.; Speck R.; Stockle M.; Trkola A.; Vernazza P.; Wandeler G.; Weber R.; Yerly S.. HIV medicine. 2020.

Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies

Sander L.; Horvath A.; Pezold S.; Andermatt S.; Amann M.; Sinnecker T.; Wendebourg M.J.; Kesenheimer E.; Yaldizli O.; Kappos L.; Granziera C.; Wuerfel J.; Cattin P.; Schlaeger R.. Frontiers in neuroscience. 2020.

Laminar analysis of the cerebellar cortex shows widespread damage in early MS patients: A pilot study at 7T MRI.

Galbusera R; Parmar K; Boillat Y; Fartaria MJ; Todea AR; Brien KO; Smolinski A; Kappos L; van der Zwaag W; Granziera C. Multiple sclerosis journal - experimental, translational and clinical. 2020.

Method and system for monitoring a biological process.

Fartaria M.J.; Mortamet B.; Kober T. Bach-Cuadra M.; Granziera C.. . 2020.

Multiple sclerosis cortical and WM lesion segmentation at 3T MRI: a deep learning method based on FLAIR and MP2RAGE.

La Rosa F; Abdulkadir A; Fartaria MJ; Rahmanzadeh R; Lu PJ; Galbusera R; Barakovic M; Thiran JP; Granziera C; Cuadra MB. NeuroImage-Clinical. 2020.

New and enlarging white matter lesions adjacent to the ventricle system and thalamic atrophy are independently associated with lateral ventricular enlargement in multiple sclerosis.

Sinnecker T; Ruberte E; Schädelin S; Canova V; Amann M; Naegelin Y; Penner IK; Müller J; Kuhle J; Décard B; Derfuss T; Kappos L; Granziera C; Wuerfel J; Magon S; Yaldizli Ö. Journal of neurology. 2020.

Quantitative brain relaxation atlases for personalized detection and characterization of brain pathology.

Piredda GF; Hilbert T; Granziera C; Bonnier G; Meuli R; Molinari F; Thiran JP; Kober T. Magnetic Resonance in Medicine. 2020.

Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis

Cristina Granziera; Jens Wuerfel; Frederik Barkhof; Massimiliano Calabrese; Nicola De Stefano; Christian Enzinger; Nikos Evangelou; Massimo Filippi; Jeroen J.G. Geurt; Daniel S. Reich; Maria A. Rocca; Stefan Ropele; Àlex Rovira; Pascal Sati; Ahmed T. Toosy; Hugo Vrenken; Claudia A. M. Gandini Wheeler-Kingshott; Ludwig Kappos. . 2020.

RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis.

Barquero G; La Rosa F; Kebiri H; Lu PJ; Rahmanzadeh R; Weigel M; Fartaria MJ; Kober T; Théaudin M; Du Pasquier R; Sati P; Reich DS; Absinta M; Granziera C; Maggi P; Bach Cuadra M. NeuroImage-Clinical. 2020.

The Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study: baseline participant profile

Metral M.; Darling K.E.A.; Locatelli I.; Nadin I.; Santos G.; Brugger P.; Kovari H.; Cusini A.; Gutbrod K.; Tarr P.E.; Calmy A.; Lecompte T.D.; Assal F.; Monsch A.U.; Kunze U.; Stoeckle M.; Schwind M.; Schmid P.; Pignatti R.; Di Benedetto C.; Du Pasquier R.; Cavassini M.; Cavassini M.; Du Pasquier R.; Metral M.; Simioni S.; Brugger P.; Gutbrod K.; Monsch A.U.; Kunze U.; Schneitter M.; Nadin I.; Fruh S.; Schwind M.; Pignatti R.; Clarke S.; Assal F.; Derfuss T.; von Arx S.; Eisele G.; Sacco L.; Bertschi M.; Hundsberger T.; Du Pasquier R.; Calmy A.; Hauser C.; Cusini A.; Weber R.; Kovari H.; Hasse B.; Stoeckle M.; Fux C.; Bernasconi E.; Di Benedetto C.; Bruno A.; Schmid P.; Darling K.; Cavassini M.; Scherrer A.; Scherrer A.; Vallet Y.; Alves D.; Locatelli I.; Decosterd L.; Granziera C.; Krueger G.; Meuli R.; Vargas M.. HIV medicine. 2020.

Accurate, rapid and reliable, fully automated MRI brainstem segmentation for application in multiple sclerosis and neurodegenerative diseases.

Sander L; Pezold S; Andermatt S; Amann M; Meier D; Wendebourg MJ; Sinnecker T; Radue EW; Naegelin Y; Granziera C; Kappos L; Wuerfel J; Cattin P; Schlaeger R; Alzheimer's Disease Neuroimaging Initiative. Human brain mapping. 2019.

A fully automated approach for differential diagnosis support in multiple sclerosis based on the central vein sign

Fartaria, M. J.; Maggi, P.; Sati, P.; Reich, D. S.; Granziera, C.; Du Pasquier, R.; Meuli, R.; Cuadra, M. Bach; Richiardi, J.; Kober, T.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

An evaluation of axonal and myelin damage in multiple sclerosis lesions in living patients using myelin water and multi-shell diffusion MRI

Rahmanzadeh, R.; Lu, P. -J.; Weigel, M.; Nguyen, T. D.; Schiavi, S.; Wang, Y.; Radue, E. -W.; Kuhle, J.; Kappos, L.; Granziera, C.. European Journal of Neurology . 2019.

Automated Detection and Segmentation of Multiple Sclerosis Lesions Using Ultra-High-Field MP2RAGE.

Fartaria MJ; Sati P; Todea A; Radue EW; Rahmanzadeh R; OʼBrien K; Reich DS; Bach Cuadra M; Kober T; Granziera C. Investigative radiology. 2019.

Axonal and myelin injury in white matter and cortex of relapsing-remitting and progressive multiple sclerosis patients: a combined myelin water and multi-shell diffusion MRI study

Rahmanzadeh, R.; Lu, P. -J.; Weigel, M.; Galbusera, R.; Nguyen, T. D.; Schiavi, S.; Wang, Y.; La Rosa, F.; Cuadra, M. Bach; Radue, E. -W.; Kuhle, J.; Kappos, L.; Granziera, C.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

Axonal damage explains part of and extends beyond the diffuse pathology evidenced by T1 mapping in normal-appearing white matter of multiple sclerosis patients

Rahmanzadeh, R.; Lu, P. -J.; Weigel, M.; Galbusera, R.; La Rosa, F.; Cuadra, M. Bach; Schiavi, S.; Radue, E. -W.; Kuhle, J.; Kappos, L.; Granziera, C.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

Can diffusion MRI reveal stroke-induced microstructural changes in GM?

Brusini L.; Galazzo I.B.; Zucchelli M.; Granziera C.; Menegaz G.. . 2019.

Cerebellar cortical laminar analysis of T1 relaxation times at 7T MRI shows widespread cerebellar cortex damage in early relapsing-remitting MS patients but no correlation with clinical deficits

Galbusera, R.; Parmar, K.; Boillat, Y.; O'Brien, K.; Kappos, L.; Van der Zwaag, W.; Granziera, C.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

Classification of multiple sclerosis patients based on patterns of volume loss in the CNS

Tsagkas, C.; Parmar, K.; Pezold, S.; Barro, C.; Chakravarty, M. M.; Gaetano, L.; Naegelin, Y.; Amann, M.; Papadopoulou, A.; Wuerfel, J.; Kappos, L.; Kuhle, J.; Sprenger, T.; Granziera, C.; Magon, S.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

Cortical laminar assessment of T1 and T2*in the cerebellum of MS patients and controls at 7T MRI

Galbusera, R.; Boillat, Y.; Brien, K. O'; Kappos, L.; Van der Zwaag, W.; Granziera, C.. European Journal of Neurology . 2019.

Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland.

Santos GMA; Locatelli I; Métral M; Calmy A; Lecompte TD; Nadin I; Hauser C; Cusini A; Hasse B; Kovari H; Tarr P; Stoeckle M; Fux C; Di Benedetto C; Schmid P; Darling KEA; Du Pasquier R; Cavassini M; Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) Study Group.. Open forum infectious diseases. 2019.

Deep learning analysis applied to multi-parametric advanced MRI shows higher myelin content and neurite density in juxtacortical lesions compared to periventricular lesions

Lu, P. -J.; Rahmanzadeh, R.; Galbusera, R.; Odry, B.; Weigel, M.; La Rosa, F.; Cuadra, M. Bach; Nguyen, T.; Wang, Y.; Daducci, A.; Kuhle, J.; Cattin, P.; Kappos, L.; Granziera, C.. Multiple sclerosis (Houndmills, Basingstoke, England). 2019.

Imaging of neuroinflammation in migraine with aura: A [(11)C]PBR28 PET/MRI study.

Albrecht DS; Mainero C; Ichijo E; Ward N; Granziera C; Zürcher NR; Akeju O; Bonnier G; Price J; Hooker JM; Napadow V; Loggia ML; Hadjikhani N. Neurology. 2019.

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis.

Fartaria MJ; Kober T; Granziera C; Bach Cuadra M. NeuroImage-Clinical. 2019.

Personalized pathology maps to quantify diffuse and focal brain damage.

Bonnier G; Fischi-Gomez E; Roche A; Hilbert T; Kober T; Krueger G; Granziera C. NeuroImage-Clinical. 2019.

Shallow vs deep learning architectures for white matter lesion segmentation in the early stages of multiple sclerosis

La Rosa F.; Fartaria M.J.; Kober T.; Richiardi J.; Granziera C.; Thiran J.-P.; Cuadra M.B.. . 2019.

Central Slab versus Whole Brain to Measure Brain Atrophy in Multiple Sclerosis.

Ruberte E; Sinnecker T; Amann M; Gaetano L; Naegelin Y; Penner IK; Kuhle J; Derfuss T; Kappos L; Granziera C; Wuerfel J; Yaldizli Ö. European Neurology. 2018.

Correction to In Vivo Imaging of Human Neuroinflammation.

Albrecht DS; Granziera C; Hooker JM; Loggia ML. ACS Chemical Neuroscience. 2018.

Future Brain and Spinal Cord Volumetric Imaging in the Clinic for Monitoring Treatment Response in MS.

Sinnecker T; Granziera C; Wuerfel J; Schlaeger R. Current treatment options in neurology. 2018.

On the Viability of Diffusion MRI-Based Microstructural Biomarkers in Ischemic Stroke.

Boscolo Galazzo I; Brusini L; Obertino S; Zucchelli M; Granziera C; Menegaz G. Frontiers in neuroscience. 2018.

Partial volume-aware assessment of multiple sclerosis lesions.

Fartaria MJ; Todea A; Kober T; O'brien K; Krueger G; Meuli R; Granziera C; Roche A; Bach Cuadra M. NeuroImage-Clinical. 2018.

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis.

Barro C; Benkert P; Disanto G; Tsagkas C; Amann M; Naegelin Y; Leppert D; Gobbi C; Granziera C; Yaldizli Ö; Michalak Z; Wuerfel J; Kappos L; Parmar K; Kuhle J. Brain : a journal of neurology. 2018.

Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI.

Boillat Y; Bazin PL; O'Brien K; Fartaria MJ; Bonnier G; Krueger G; van der Zwaag W; Granziera C. NeuroImage. 2018.

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE.

Fartaria MJ; OʼBrien K; Şorega A; Bonnier G; Roche A; Falkovskiy P; Krueger G; Kober T; Bach Cuadra M; Granziera C. Investigative radiology. 2017.

Aspect pronostiques et prédictifs de la réponse au traitement : la recherche de marqueurs IRM.

Granziera C.; Fischi E.; Maarouf A.; Pelletier J.. . 2017.

Rivastigmine decreases brain damage in HIV patients with mild cognitive deficits.

Perrotta G; Bonnier G; Meskaldji DE; Romascano D; Aydarkhanov R; Daducci A; Simioni S; Cavassini M; Metral M; Lazeyras F; Meuli R; Krueger G; Du Pasquier RA; Granziera C. Annals of Clinical and Translational Neurology. 2017.

The Combined Quantification and Interpretation of Multiple Quantitative Magnetic Resonance Imaging Metrics Enlightens Longitudinal Changes Compatible with Brain Repair in Relapsing-Remitting Multiple Sclerosis Patients.

Bonnier G; Maréchal B; Fartaria MJ; Falkowskiy P; Marques JP; Simioni S; Schluep M; Du Pasquier R; Thiran JP; Krueger G; Granziera C. Frontiers in neurology. 2017.

A New Approach for Deep Gray Matter Analysis Using Partial-Volume Estimation.

Bonnier G; Kober T; Schluep M; Du Pasquier R; Krueger G; Meuli R; Granziera C; Roche A. PLoS One. 2016.