Departement
Klinische Forschung
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Publications Martin Ivan

An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes.

Viswanathan S; Blanc KL; Ciccocioppo R; Dagher G; Filiano AJ; Galipeau J; Krampera M; Krieger L; Lalu MM; Nolta J; Rodriguez Pardo VM; Shi Y; Tarte K; Weiss DJ; Martin I. Cytotherapy. 2023.

Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity.

García-García A; Pigeot S; Martin I. Bioactive Materials. 2023.

Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies.

Muthu S; Korpershoek JV; Novais EJ; Tawy GF; Hollander AP; Martin I. Nature reviews. Rheumatology. 2023.

Good Manufacturing Practice-compliant change of raw material in the manufacturing process of a clinically used advanced therapy medicinal product-a comparability study.

Wixmerten A; Miot S; Bittorf P; Wolf F; Feliciano S; Hackenberg S; Häusner S; Krenger W; Haug M; Martin I; Pullig O; Barbero A. Cytotherapy. 2023.

Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc.

Kasamkattil J; Gryadunova A; Schmid R; Gay-Dujak MHP; Dasen B; Hilpert M; Pelttari K; Martin I; Schären S; Barbero A; Krupkova O; Mehrkens A. Frontiers in Bioengineering and Biotechnology. 2023.

Mini- and macro-scale direct perfusion bioreactors with optimized flow for engineering 3D tissues.

Born G; Plantier E; Nannini G; Caimi A; Mazzoleni A; Asnaghi MA; Muraro MG; Scherberich A; Martin I; García-García A. Biotechnology journal. 2023.

T-cadherin is a novel regulator of pericyte function during angiogenesis.

Dasen B; Pigeot S; Born GM; Verrier S; Rivero O; Dittrich PS; Martin I; Filippova M. American journal of physiology. Cell physiology. 2023.

Toward 3D Bioprinting of Osseous Tissue of Predefined Shape Using Single-Matrix Cell-Bioink Constructs.

Gu Y; Pigeot S; Ahrens L; Tribukait-Riemenschneider F; Sarem M; Wolf F; García-García A; Barbero A; Martin I; Shastri VP. Advanced Healthcare Materials. 2023.

A composite, off-the-shelf osteoinductive material for large, vascularized bone flap prefabrication.

Kouba L; Bürgin J; Born G; Perale G; Schaefer DJ; Scherberich A; Pigeot S; Martin I. Acta Biomaterialia. 2022.

An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells Committee editorial on overcoming limitations in clinical trials of mesenchymal stromal cell therapy for coronavirus disease-19: time for a global registry

Weiss D.J.; Filiano A.; Galipeau J.; Khoury M.; Krampera M.; Lalu M.; Blanc K.L.; Nolta J.; Phinney D.G.; Rocco P.R.M.; Shi Y.; Tarte K.; Viswanathan S.; Martin I.. Cytotherapy. 2022.

Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies.

Chawla S; Mainardi A; Majumder N; Dönges L; Kumar B; Occhetta P; Martin I; Egloff C; Ghosh S; Bandyopadhyay A; Barbero A. Cells. 2022.

Efficacy of bioreactor-activated bone substitute with bone marrow nuclear cells on fusion rate and fusion mass microarchitecture in sheep.

Ding M; Koroma KE; Wendt D; Martin I; Martinetti R; Jespersen S; Schrøder HD; Overgaard S. Journal of Biomedical Materials Research - Part B Applied Biomaterials. 2022.

Engineering of Tracheal Grafts Based on Recellularization of Laser-Engraved Human Airway Cartilage Substrates.

Baranovskii D; Demner J; Nürnberger S; Lyundup A; Redl H; Hilpert M; Pigeot S; Krasheninnikov M; Krasilnikova O; Klabukov I; Parshin V; Martin I; Lardinois D; Barbero A. Cartilage. 2022.

Genipin-crosslinked collagen scaffolds inducing chondrogenesis: a mechanical and biological characterization.

Scialla S; Gullotta F; Izzo D; Palazzo B; Scalera F; Martin I; Sannino A; Gervaso F. Journal of Biomedical Materials Research - Part A. 2022.

In Vitro and Ectopic In Vivo Studies toward the Utilization of Rapidly Isolated Human Nasal Chondrocytes for Single-Stage Arthroscopic Cartilage Regeneration Therapy.

Lehoczky G; Trofin RE; Vallmajo-Martin Q; Chawla S; Pelttari K; Mumme M; Haug M; Egloff C; Jakob M; Ehrbar M; Martin I; Barbero A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022.

Perfusion-Based Bioreactor Culture and Isothermal Microcalorimetry for Preclinical Drug Testing with the Carbonic Anhydrase Inhibitor SLC-0111 in Patient-Derived Neuroblastoma.

Huo Z; Bilang R; Supuran CT; von der Weid N; Bruder E; Holland-Cunz S; Martin I; Muraro MG; Gros SJ. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022.

Repair of a Rat Mandibular Bone Defect by Hypertrophic Cartilage Grafts Engineered From Human Fractionated Adipose Tissue.

Cheng C; Chaaban M; Born G; Martin I; Li Q; Schaefer DJ; Jaquiery C; Scherberich A. Frontiers in Bioengineering and Biotechnology. 2022.

Spheroid-Based Tissue Engineering Strategies for Regeneration of the Intervertebral Disc.

Kasamkattil J; Gryadunova A; Martin I; Barbero A; Schären S; Krupkova O; Mehrkens A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022.

T-cadherin Expressing Cells in the Stromal Vascular Fraction of Human Adipose Tissue: Role in Osteogenesis and Angiogenesis.

Guerrero J; Dasen B; Frismantiene A; Pigeot S; Ismail T; Schaefer DJ; Philippova M; Resink TJ; Martin I; Scherberich A. Stem Cells Translational Medicine. 2022.

Biomimetic human bone marrow tissues: models to study hematopoiesis and platforms for drug testing

Garcia-Garcia A.; Martin I.. Molecular and Cellular Oncology. 2021.

Case Report: Reconstruction of a Large Maxillary Defect With an Engineered, Vascularized, Prefabricated Bone Graft.

Ismail T; Haumer A; Lunger A; Osinga R; Kaempfen A; Saxer F; Wixmerten A; Miot S; Thieringer F; Beinemann J; Kunz C; Jaquiéry C; Weikert T; Kaul F; Scherberich A; Schaefer DJ; Martin I. Frontiers in Oncology. 2021.

Chronic inflammation and extracellular matrix-specific autoimmunity following inadvertent periarticular influenza vaccination.

Hirsiger JR; Tamborrini G; Harder D; Bantug GR; Hoenger G; Recher M; Marx C; Li QZ; Martin I; Hess C; Scherberich A; Daikeler T; Berger CT. Journal of Autoimmunity. 2021.

Comparison of Human Articular Cartilage Tissue and Chondrocytes Isolated from Peripheral versus Central Regions of Traumatic Lesions.

Acevedo L; Iselin L; Berkelaar MHM; Salzmann GM; Wolf F; Feliciano S; Vogel N; Pagenstert G; Martin I; Pelttari K; Barbero A; Arnold MP. Cartilage. 2021.

Consensus International Council for Commonality in Blood Banking Automation–International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells

Viswanathan S.; Ciccocioppo R.; Galipeau J.; Krampera M.; Le Blanc K.; Martin I.; Moniz K.; Nolta J.; Phinney D.G.; Shi Y.; Szczepiorkowski Z.M.; Tarte K.; Weiss D.J.; Ashford P.. Cytotherapy. 2021.

Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches

Garcia-Garcia A.; Klein T.; Born G.; Hilpert M.; Scherberich A.; Lengerke C.; Skoda R.C.; Bourgine P.E.; Martin I.. Proceedings of the National Academy of Sciences of the United States of America. 2021.

Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization.

Power L; Acevedo L; Yamashita R; Rubin D; Martin I; Barbero A. Osteoarthritis and Cartilage. 2021.

Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects.

Acevedo Rua L; Mumme M; Manferdini C; Darwiche S; Khalil A; Hilpert M; Buchner DA; Lisignoli G; Occhetta P; von Rechenberg B; Haug M; Schaefer DJ; Jakob M; Caplan A; Martin I; Barbero A; Pelttari K. Science Translational Medicine. 2021.

Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells

Born G.; Nikolova M.; Scherberich A.; Treutlein B.; Garcia-Garcia A.; Martin I.. Journal of Tissue Engineering. 2021.

From Single Batch to Mass Production–Automated Platform Design Concept for a Phase II Clinical Trial Tissue Engineered Cartilage Product

Haeusner S.; Herbst L.; Bittorf P.; Schwarz T.; Henze C.; Mauermann M.; Ochs J.; Schmitt R.; Blache U.; Wixmerten A.; Miot S.; Martin I.; Pullig O.. Frontiers in Medicine. 2021.

Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective.

Mainardi A; Cambria E; Occhetta P; Martin I; Barbero A; Schären S; Mehrkens A; Krupkova O. Frontiers in Bioengineering and Biotechnology. 2021.

Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration.

Pigeot S; Klein T; Gullotta F; Dupard SJ; Garcia Garcia A; García-García A; Prithiviraj S; Lorenzo P; Filippi M; Jaquiery C; Kouba L; Asnaghi MA; Raina DB; Dasen B; Isaksson H; Önnerfjord P; Tägil M; Bondanza A; Martin I; Bourgine PE. Advanced Materials. 2021.

Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition

Galipeau J.; Krampera M.; Leblanc K.; Nolta J.A.; Phinney D.G.; Shi Y.; Tarte K.; Viswanathan S.; Martin I.. Cytotherapy. 2021.

Modeling In Vitro Osteoarthritis Phenotypes in a Vascularized Bone Model Based on a Bone-Marrow Derived Mesenchymal Cell Line and Endothelial Cells.

Pirosa A; Tankus EB; Mainardi A; Occhetta P; Dönges L; Baum C; Rasponi M; Martin I; Barbero A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021.

Nasal Chondrocyte-Based Engineered Grafts for the Repair of Articular Cartilage "Kissing" Lesions: A Pilot Large-Animal Study.

Šećerović A; Pušić M; Kostešić P; Vučković M; Vukojević R; Škokić S; Sasi B; Vukasović Barišić A; Hudetz D; Vnuk D; Matičić D; Urlić I; Mumme M; Martin I; Ivković A. American Journal of Sports Medicine. 2021.

Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation.

Gryadunova A; Kasamkattil J; Gay MHP; Dasen B; Pelttari K; Mironov V; Martin I; Schären S; Barbero A; Krupkova O; Mehrkens A. Acta Biomaterialia. 2021.

Optimization of hyaluronic acid-tyramine/silk-fibroin composite hydrogels for cartilage tissue engineering and delivery of anti-inflammatory and anabolic drugs.

Ziadlou R; Rotman S; Teuschl A; Salzer E; Barbero A; Martin I; Alini M; Eglin D; Grad S. Materials Science and Engineering C. 2021.

The Survey on Cellular and Tissue-Engineered Therapies in Europe in 2016 and 2017.

Gay MHP; Baldomero H; Farge-Bancel D; Robey PG; Rodeo S; Passweg J; Müller-Gerbl M; Martin I. Tissue engineering. Part A. 2021.

Thymus Extracellular Matrix-Derived Scaffolds Support Graft-Resident Thymopoiesis and Long-Term In Vitro Culture of Adult Thymic Epithelial Cells

Asnaghi M.A.; Barthlott T.; Gullotta F.; Strusi V.; Amovilli A.; Hafen K.; Srivastava G.; Oertle P.; Toni R.; Wendt D.; Hollander G.A.; Martin I.. Advanced Functional Materials. 2021.

Advanced Bioink for 3D Bioprinting of Complex Free-Standing Structures with High Stiffness.

Gu Y; Schwarz B; Forget A; Barbero A; Martin I; Shastri VP. Bioengineering. 2020.

Anti-Inflammatory and Chondroprotective Effects of Vanillic Acid and Epimedin C in Human Osteoarthritic Chondrocytes.

Ziadlou R; Barbero A; Martin I; Wang X; Qin L; Alini M; Grad S. Biomolecules. 2020.

Biomarker Signatures of Quality for Engineering Nasal Chondrocyte-Derived Cartilage.

Asnaghi MA; Power L; Barbero A; Haug M; Köppl R; Wendt D; Martin I. Frontiers in Bioengineering and Biotechnology. 2020.

Blockage of bone morphogenetic protein signalling counteracts hypertrophy in a human osteoarthritic micro-cartilage model.

Chawla S; Berkelaar MHM; Dasen B; Halleux C; Guth-Gundel S; Kramer I; Ghosh S; Martin I; Barbero A; Occhetta P. Journal of cell science. 2020.

Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential.

Khoury M; Rocco PRM; Phinney DG; Krampera M; Martin I; Viswanathan S; Nolta JA; LeBlanc K; Galipeau J; Weiss DJ. Cytotherapy. 2020.

Dispersion of ceramic granules within human fractionated adipose tissue to enhance endochondral bone formation.

Huang RL; Guerrero J; Senn AS; Kappos EA; Liu K; Li Q; Dufrane D; Schaefer DJ; Martin I; Scherberich A. Acta Biomaterialia. 2020.

Editorial: Clinical Translation and Commercialisation of Advanced Therapy Medicinal Products

Martin I.; Bayon Y.; Yu T.T.L.; Vertes A.A.. Frontiers in Bioengineering and Biotechnology. 2020.

Expanded cells, bone marrow, adipose tissue: what is (not) allowed in Switzerland: Focus: cartilage regeneration and arthrosis Expandierte Zellen, Knochenmark, Fettgewebe: Was ist in der Schweiz (nicht) erlaubt?: Fokus: Knorpelregeneration und Arthrose

Mumme M.; Wixmerten A.; Steinwachs M.; Martin I.. Arthroskopie. 2020.

Extracellular Matrix Production by Mesenchymal Stromal Cells in Hydrogels Facilitates Cell Spreading and Is Inhibited by FGF-2.

Horton ER; Vallmajo-Martin Q; Martin I; Snedeker JG; Ehrbar M; Blache U. Advanced Healthcare Materials. 2020.

Human dental pulp stem cells exhibit enhanced properties in comparison to human bone marrow stem cells on neurites outgrowth.

Pagella P; Miran S; Neto E; Martin I; Lamghari M; Mitsiadis TA. FASEB Journal. 2020.

Intra-individual comparison of human nasal chondrocytes and debrided knee chondrocytes: Relevance for engineering autologous cartilage grafts.

Lehoczky G; Wolf F; Mumme M; Gehmert S; Miot S; Haug M; Jakob M; Martin I; Barbero A. Clinical hemorheology and microcirculation. 2020.

Orthotopic bone formation by streamlined engineering and devitalization of human hypertrophic cartilage

Pigeot S.; Bourgine P.E.; Claude J.; Scotti C.; Papadimitropoulos A.; Todorov A.; Epple C.; Peretti G.M.; Martin I.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020.

Platelet-rich plasma and stromal vascular fraction cells for the engineering of axially vascularized osteogenic grafts.

Ismail T; Lunger A; Haumer A; Todorov A; Menzi N; Schweizer T; Bieback K; Bürgin J; Schaefer DJ; Martin I; Scherberich A. Journal of Tissue Engineering and Regenerative Medicine. 2020.

Reply to comment on: Mumme M, et al. Tissue engineering for paediatric patients. Swiss Med Wkly. 2019.149.w20032.

Mumme M; Wixmerten A; Martin I. . 2020.

Sensing tissue engineered cartilage quality with Raman spectroscopy and statistical learning for the development of advanced characterization assays.

Power LJ; Fasolato C; Barbero A; Wendt DJ; Wixmerten A; Martin I; Asnaghi MA. Biosensors and Bioelectronics. 2020.

Welcome to ISCT 2020 Paris Virtual.

Chabannon C; Ciccocioppo R; Martin I. . 2020.

Bioreactor-manufactured cartilage grafts repair acute and chronic osteochondral defects in large animal studies.

Vukasovic A; Asnaghi MA; Kostesic P; Quasnichka H; Cozzolino C; Pusic M; Hails L; Trainor N; Krause C; Figallo E; Filardo G; Kon E; Wixmerten A; Maticic D; Pellegrini G; Kafienah W; Hudetz D; Smith T; Martin I; Ivkovic A; Wendt D. CELL PROLIFERATION. 2019.

Challenges for mesenchymal stromal cell therapies

Martin I.; Galipeau J.; Kessler C.; Blanc K.L.; Dazzi F.. Science Translational Medicine. 2019.

Challenges Toward the Identification of Predictive Markers for Human Mesenchymal Stromal Cells Chondrogenic Potential.

Stüdle C; Occhetta P; Geier F; Mehrkens A; Barbero A; Martin I. Stem Cells Translational Medicine. 2019.

Erratum to “Engineered humanized bone organs maintain human hematopoiesis in vivo”: (Experimental Hematology (2018) 61 (45–51.e5), (S0301472X18300389), (10.1016/j.exphem.2018.01.004))

Fritsch K.; Pigeot S.; Feng X.; Bourgine P.E.; Schroeder T.; Martin I.; Manz M.G.; Takizawa H.. Experimental Hematology. 2019.

Extracellular Matrices to Modulate the Innate Immune Response and Enhance Bone Healing.

García-García A; Martin I. Frontiers in Immunology. 2019.

Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs.

Bourgine PE; Fritsch K; Pigeot S; Takizawa H; Kunz L; Kokkaliaris KD; Coutu DL; Manz MG; Martin I; Schroeder T. iScience. 2019.

Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model.

Occhetta P; Mainardi A; Votta E; Vallmajo-Martin Q; Ehrbar M; Martin I; Barbero A; Rasponi M. Nature Biomedical Engineering. 2019.

Improved Adipocyte Viability in Autologous Fat Grafting With Ascorbic Acid-Supplemented Tumescent Solution.

Lunger A; Ismail T; Todorov A; Buergin J; Lunger F; Oberhauser I; Haug M; Kalbermatten DF; Largo RD; Martin I; Scherberich A; Schaefer DJ. Annals of plastic surgery. 2019.

Magnetic nanocomposite hydrogels and static magnetic field stimulate the osteoblastic and vasculogenic profile of adipose-derived cells.

Filippi M; Dasen B; Guerrero J; Garello F; Isu G; Born G; Ehrbar M; Martin I; Scherberich A. Biomaterials. 2019.

Maintenance of primary human colorectal cancer microenvironment using a perfusion bioreactor-based 3D culture system.

59. Manfredonia C, Muraro MG, Hirt C, Mele V, Governa V, Papadimitropoulos A, Däster S, Soysal SD; Droeser RA; Mechera R; Oertli D; Rosso R; Bolli M; Zettl A; Terracciano LM; Spagnoli GC; Martin I; Iezzi G. . 2019.

Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature.

Viswanathan S; Shi Y; Galipeau J; Krampera M; Leblanc K; Martin I; Nolta J; Phinney DG; Sensebe L. Cytotherapy. 2019.

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments.

Blache U; Horton ER; Xia T; Schoof EM; Blicher LH; Schönenberger A; Snedeker JG; Martin I; Erler JT; Ehrbar M. Life Science Alliance. 2019.

Nose to back: Compatibility of nasal chondrocytes with environmental conditions mimicking a degenerated intervertebral disc

Gay M.H.P.; Mehrkens A.; Rittmann M.; Haug M.; Barbero A.; Martin I.; Schaeren S.. European Cells and Materials. 2019.

Organs by design: Can bioprinting meet self-organization?

Martin I.; Malda J.; Rivron N.C.. Current Opinion in Organ Transplantation. 2019.

Prefabrication of a large pedicled bone graft by engineering the germ for de novo vascularization and osteoinduction.

Epple C; Haumer A; Ismail T; Lunger A; Scherberich A; Schaefer DJ; Martin I. Biomaterials. 2019.

Raman spectroscopy quality controls for GMP compliant manufacturing of tissue engineered cartilage

Power L.; Wixmerten A.; Wendt D.; Barbero A.; Martin I.. . 2019.

Regulation of Inflammatory Response in Human Osteoarthritic Chondrocytes by Novel Herbal Small Molecules.

Ziadlou R; Barbero A; Stoddart MJ; Wirth M; Li Z; Martin I; Wang XL; Qin L; Alini M; Grad S. International Journal of Molecular Sciences. 2019.

Roadmap and challenges for investigator initiated clinical trials with advanced therapy medicinal products (ATMPs)

Wixmerten A.; Miot S.; Martin I.. . 2019.

Tissue engineering for paediatric patients.

Mumme M; Wixmerten A; Miot S; Barbero A; Kaempfen A; Saxer F; Gehmert S; Krieg A; Schaefer DJ; Jakob M; Martin I. Swiss medical weekly. 2019.

An In Vitro Bone Model to Investigate the Role of Triggering Receptor Expressed on Myeloid Cells-2 in Bone Homeostasis

Rossi E.; Mracsko E.; Papadimitropoulos A.; Allafi N.; Reinhardt D.; Mehrkens A.; Martin I.; Knuesel I.; Scherberich A.. Tissue Eng Part C Methods. 2018.

Biomechanical evaluation of hMSCs-based engineered cartilage for chondral tissue regeneration

Gullotta F.; Izzo D.; Scalera F.; Palazzo B.; Martin I.; Sannino A.; Gervaso F.. Journal of the Mechanical Behavior of Biomedical Materials. 2018.

Chondrogenic differentiation of human chondrocytes cultured in the absence of ascorbic acid.

Asnaghi MA; Duhr R; Quasnichka H; Hollander AP; Kafienah W; Martin I; Wendt D. Journal of Tissue Engineering and Regenerative Medicine. 2018.

Decoration of RGD-mimetic porous scaffolds with engineered and devitalized extracellular matrix for adipose tissue regeneration.

Rossi E; Guerrero J; Aprile P; Tocchio A; Kappos EA; Gerges I; Lenardi C; Martin I; Scherberich A. Acta Biomaterialia. 2018.

Delivery of cellular factors to regulate bone healing

Haumer A.; Bourgine P.E.; Occhetta P.; Born G.; Tasso R.; Martin I.. Advanced Drug Delivery Reviews. 2018.

Developmentally inspired programming of adult human mesenchymal stromal cells toward stable chondrogenesis

Occhetta P.; Pigeot S.; Rasponi M.; Dasen B.; Mehrkens A.; Ullrich T.; Kramer I.; Guth-Gundel S.; Barbero A.; Martin I.. Proceedings of the National Academy of Sciences of the United States of America. 2018.

Ectopic bone formation by aggregated mesenchymal stem cells from bone marrow and adipose tissue: A comparative study

Fennema E.M.; Tchang L.A.H.; Yuan H.; van Blitterswijk C.A.; Martin I.; Scherberich A.; de Boer J.. Journal of Tissue Engineering and Regenerative Medicine. 2018.

Engineered humanized bone organs maintain human hematopoiesis in vivo

Fritsch K.; Pigeot S.; Feng X.; Bourgine P.E.; Schroeder T.; Martin I.; Manz M.G.; Takizawa H.. Experimental Hematology. 2018.

Engineering Human Bone Marrow Proxies.

Bourgine PE; Martin I; Schroeder T. Cell Stem Cell. 2018.

Fractionated human adipose tissue as a native biomaterial for the generation of a bone organ by endochondral ossification.

Guerrero J; Pigeot S; Müller J; Schaefer DJ; Martin I; Scherberich A. Acta Biomaterialia. 2018.

From Tissue Engineering to Regenerative Surgery.

Martin I; Jakob M; Schaefer DJ. eBioMedicine. 2018.

Hyperstimulation of CaSR in human MSCs by biomimetic apatite inhibits endochondral ossification via temporal down-regulation of PTH1R

Sarem M.; Heizmann M.; Barbero A.; Martin I.; Prasad Shastri V.. Proceedings of the National Academy of Sciences of the United States of America. 2018.

Improved tendon healing using bFGF, BMP-12 and TGFβ1 in a rat model.

Majewski M; Heisterbach P; Jaquiéry C; Dürselen L; Todorov A; Martin I; Evans CH; Müller SA. European Cells and Materials. 2018.

Interplay between stiffness and degradation of architectured gelatin hydrogels leads to differential modulation of chondrogenesis in vitro and in vivo

Sarem M.; Arya N.; Heizmann M.; Neffe A.T.; Barbero A.; Gebauer T.P.; Martin I.; Lendlein A.; Shastri V.P.. Acta Biomaterialia. 2018.

In vitro biomimetic engineering of a human hematopoietic niche with functional properties.

Bourgine PE; Klein T; Paczulla AM; Shimizu T; Kunz L; Kokkaliaris KD; Coutu DL; Lengerke C; Skoda R; Schroeder T; Martin I. Proceedings of the National Academy of Sciences of the United States of America. 2018.

Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels.

Devaud YR; Avilla-Royo E; Trachsel C; Grossmann J; Martin I; Lutolf MP; Ehrbar M. Advanced Healthcare Materials. 2018.

Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating

Loeffler D.; Wang W.; Hopf A.; Hilsenbeck O.; Bourgine P.E.; Rudolf F.; Martin I.; Schroeder T.. Blood. 2018.

Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

Blache U.; Vallmajo-Martin Q.; Horton E.R.; Guerrero J.; Djonov V.; Scherberich A.; Erler J.T.; Martin I.; Snedeker J.G.; Milleret V.; Ehrbar M.. EMBO Reports. 2018.

Pre-transplantational Control of the Post-transplantational Fate of Human Pluripotent Stem Cell-Derived Cartilage.

Lee JY; Matthias N; Pothiawala A; Ang BK; Lee M; Li J; Sun D; Pigeot S; Martin I; Huard J; Huang Y; Nakayama N. Stem Cell Reports. 2018.

Proceedings of the signature series symposium "cellular therapies for orthopaedics and musculoskeletal disease proven and unproven therapies-promise, facts and fantasy," international society for cellular therapies, montreal, canada, may 2, 2018.

Piuzzi NS; Dominici M; Long M; Pascual-Garrido C; Rodeo S; Huard J; Guicheux J; McFarland R; Goodrich LR; Maddens S; Robey PG; Bauer TW; Barrett J; Barry F; Karli D; Chu CR; Weiss DJ; Martin I; Jorgensen C; Muschler GF. Cytotherapy. 2018.

Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues.

Stüdle C; Vallmajó-Martín Q; Haumer A; Guerrero J; Centola M; Mehrkens A; Schaefer DJ; Ehrbar M; Barbero A; Martin I. Biomaterials. 2018.

The survey on cellular and tissue-engineered therapies in Europe and neighboring Eurasian countries in 2014 and 2015

Ireland H.; Gay M.H.P.; Baldomero H.; De Angelis B.; Baharvand H.; Lowdell M.W.; Passweg J.; Martin I.. Cytotherapy. 2018.

Wet milling of large quantities of human excision adipose tissue for the isolation of stromal vascular fraction cells.

Menzi N; Osinga R; Todorov A; Schaefer DJ; Martin I; Scherberich A. CYTOTECHNOLOGY. 2018.

Ascorbic acid attenuates senescence of human osteoarthritic osteoblasts

Burger M.G.; Steinitz A.; Geurts J.; Pippenger B.E.; Schaefer D.J.; Martin I.; Barbero A.; Pelttari K.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017.

Bimodal morphological analyses of native and engineered tissues.

Jalili-Firoozinezhad S; Martin I; Scherberich A. Materials Science and Engineering C. 2017.

Contrast-Enhanced Microtomographic Characterisation of Vessels in Native Bone and Engineered Vascularised Grafts Using Ink-Gelatin Perfusion and Phosphotungstic Acid.

Sutter S; Todorov A; Ismail T; Haumer A; Fulco I; Schulz G; Scherberich A; Kaempfen A; Martin I; Schaefer DJ. Contrast media & molecular imaging. 2017.

Engineered, axially-vascularized osteogenic grafts from human adipose-derived cells to treat avascular necrosis of bone in a rat model.

Ismail T; Osinga R; Todorov A Jr; Haumer A; Tchang LA; Epple C; Allafi N; Menzi N; Largo RD; Kaempfen A; Martin I; Schaefer DJ; Scherberich A. Acta Biomaterialia. 2017.

Engineered Extracellular Matrices as Biomaterials of Tunable Composition and Function

Bourgine P.E.; Gaudiello E.; Pippenger B.; Jaquiery C.; Klein T.; Pigeot S.; Todorov A.; Feliciano S.; Banfi A.; Martin I.. Advanced Functional Materials. 2017.

Engineering of an angiogenic niche by perfusion culture of adipose-derived stromal vascular fraction cells.

Cerino G; Gaudiello E; Muraro MG; Eckstein F; Martin I; Scherberich A; Marsano A. Scientific Reports. 2017.

Extracellular matrix and α 5 β 1 integrin signaling control the maintenance of bone formation capacity by human adipose-derived stromal cells

Di Maggio N.; Martella E.; Frismantiene A.; Resink T.J.; Schreiner S.; Lucarelli E.; Jaquiery C.; Schaefer D.J.; Martin I.; Scherberich A.. Scientific Reports. 2017.

Low osmolality and shear stress during liposuction impair cell viability in autologous fat grafting.

Ismail T; Bürgin J; Todorov A; Osinga R; Menzi N; Largo RD; Haug M; Martin I; Scherberich A; Schaefer DJ. Journal of Plastic, Reconstructive and Aesthetic Surgery. 2017.

Monocytes Seeded on Engineered Hypertrophic Cartilage Do Not Enhance Endochondral Ossification Capacity

Todorov A.; Scotti C.; Barbero A.; Scherberich A.; Papadimitropoulos A.; Martin I.. Tissue engineering. Part A. 2017.

Nasal chondrocytes as a neural crest-derived cell source for regenerative medicine.

Pelttari K; Mumme M; Barbero A; Martin I. Current Opinion in Biotechnology. 2017.

Ontogenic Identification and Analysis of Mesenchymal Stromal Cell Populations during Mouse Limb and Long Bone Development

Nusspaumer G.; Jaiswal S.; Barbero A.; Reinhardt R.; Ishay Ronen D.; Haumer A.; Lufkin T.; Martin I.; Zeller R.. Stem Cell Reports. 2017.

Perfusion bioreactor-based cryopreservation of 3D human mesenchymal stromal cell tissue grafts

Petrenko Y.A.; Petrenko A.Y.; Martin I.; Wendt D.. CRYOBIOLOGY. 2017.

Pericytes Accelerate the in vivo Angiogenesis in mm-Thick Engineered Tissues

Marsano, Anna; Cerino, Giulia; Gaudiello, Emanuele; Muraro, Manuele Giuseppe; Martin, Ivan; Eckstein, Friedrich; Scherberich, Arnaud. Journal of vascular research. 2017.

Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications

Jalili-Firoozinezhad S.; Mohamadzadeh Moghadam M.H.; Ghanian M.H.; Ashtiani M.K.; Alimadadi H.; Baharvand H.; Martin I.; Scherberich A.. RSC Advances. 2017.

Pooled thrombin-activated platelet-rich plasma: a substitute for fetal bovine serum in the engineering of osteogenic/vasculogenic grafts

Tchang L.A.; Pippenger B.E.; Todorov A.; Wolf F.; Burger M.G.; Jaquiery C.; Bieback K.; Martin I.; Schaefer D.J.; Scherberich A.. Journal of Tissue Engineering and Regenerative Medicine. 2017.

Scaffold Composition Determines the Angiogenic Outcome of Cell-Based Vascular Endothelial Growth Factor Expression by Modulating Its Microenvironmental Distribution.

Gaudiello E; Melly L; Cerino G; Boccardo S; Jalili-Firoozinezhad S; Xu L; Eckstein F; Martin I; Kaufmann BA; Banfi A; Marsano A. Advanced Healthcare Materials. 2017.

Synthetic niche substrates engineered via two-photon laser polymerization for the expansion of human mesenchymal stromal cells

Nava M.M.; Di Maggio N.; Zandrini T.; Cerullo G.; Osellame R.; Martin I.; Raimondi M.T.. Journal of Tissue Engineering and Regenerative Medicine. 2017.

Vascular endothelial growth factor sequestration enhances in vivo cartilage formation

Medeiros Da Cunha C.M.; Perugini V.; Bernegger P.; Centola M.; Barbero A.; Guildford A.L.; Santin M.; Banfi A.; Martin I.; Marsano A.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017.

A relativity concept in mesenchymal stromal cell manufacturing

Martin I.; De Boer J.; Sensebe L.. Cytotherapy. 2016.

Biologically and mechanically driven design of an RGD-mimetic macroporous foam for adipose tissue engineering applications

Rossi E.; Gerges I.; Tocchio A.; Tamplenizza M.; Aprile P.; Recordati C.; Martello F.; Martin I.; Milani P.; Lenardi C.. Biomaterials. 2016.

Cartilage Repair in the Inflamed Joint: Considerations for Biological Augmentation Toward Tissue Regeneration.

Scotti C; Gobbi A; Karnatzikos G; Martin I; Shimomura K; Lane JG; Peretti GM; Nakamura N. Tissue Engineering Part B-Reviews. 2016.

Characterization of vasculogenic potential of human adipose-derived endothelial cells in a three-dimensional vascularized skin substitute

Klar A.S.; Guven S.; Zimoch J.; Zapiorkowska N.A.; Biedermann T.; Bottcher-Haberzeth S.; Meuli-Simmen C.; Martin I.; Scherberich A.; Reichmann E.; Meuli M.. Pediatric surgery international. 2016.

Dual Role of Mesenchymal Stem Cells Allows for Microvascularized Bone Tissue-Like Environments in PEG Hydrogels

Blache U.; Metzger S.; Vallmajo-Martin Q.; Martin I.; Djonov V.; Ehrbar M.. Advanced Healthcare Materials. 2016.

Engineered mesenchymal cell-based patches as controlled VEGF delivery systems to induce extrinsic angiogenesis.

Boccardo S; Gaudiello E; Melly L; Cerino G; Ricci D; Martin I; Eckstein F; Banfi A; Marsano A. Acta Biomaterialia. 2016.

Engineered miniaturized models of musculoskeletal diseases

Bersini S.; Arrigoni C.; Lopa S.; Bongio M.; Martin I.; Moretti M.. Drug Discovery Today. 2016.

Engineering small-scale and scaffold-based bone organs via endochondral ossification using adult progenitor cells

Scotti C.; Tonnarelli B.; Papadimitropoulos A.; Piccinini E.; Todorov A.; Centola M.; Barbero A.; Martin I.. Methods in Molecular Biology. 2016.

Fat-derived stromal vascular fraction cells enhance the bone forming capacity of devitalized engineered hypertrophic cartilage matrix

Todorov A; Kreutz M; Haumer A; Scotti C; Barbero A; Bourgine PE; Scherberich A; Jaquiery C; Martin I. . 2016.

Fat-Derived Stromal Vascular Fraction Cells Enhance the Bone-Forming Capacity of Devitalized Engineered Hypertrophic Cartilage Matrix.

Todorov A; Kreutz M; Haumer A; Scotti C; Barbero A; Bourgine PE; Scherberich A; Jaquiery C; Martin I. Stem Cells Translational Medicine. 2016.

Future of cellular therapies in orthopaedics: Different views, one common challenge

Martin I.; Duhr R.. Journal of Orthopaedic Research. 2016.

Generationofaboneorganby humanadipose-derived stromal cells through endochondral ossification

Osinga R.; Di Maggio N.; Todorov A.; Allafi N.; Barbero A.; Laurent F.; Schaefer D.J.; Martin I.; Scherberich A.. Stem Cells Translational Medicine. 2016.

Implantation of Stromal Vascular Fraction Progenitors at Bone Fracture Sites: From a Rat Model to a First-in-Man Study.

Saxer F; Scherberich A; Todorov A; Studer P; Miot S; Schreiner S; Güven S; Tchang LA; Haug M; Heberer M; Schaefer DJ; Rikli D; Martin I; Jakob M. Stem Cells. 2016.

In Memoriam: Paolo Bianco

Martin I.; Centola M.; Piccinini E.. Current Stem Cell Reports. 2016.

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials.

Galipeau J; Krampera M; Barrett J; Dazzi F; Deans RJ; DeBruijn J; Dominici M; Fibbe WE; Gee AP; Gimble JM; Hematti P; Koh MB; LeBlanc K; Martin I; McNiece IK; Mendicino M; Oh S; Ortiz L; Phinney DG; Planat V; Shi Y; Stroncek DF; Viswanathan S; Weiss DJ; Sensebe L. Cytotherapy. 2016.

Learn, simplify and implement: developmental re-engineering strategies for cartilage repai.

Occhetta P; Stüdle C; Barbero A; Martin I. Swiss medical weekly. 2016.

Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational first-in-human trial.

Mumme M; Barbero A; Miot S; Wixmerten A; Feliciano S; Wolf F; Asnaghi AM; Baumhoer D; Bieri O; Kretzschmar M; Pagenstert G; Haug M; Schaefer DJ; Martin I; Jakob M. The Lancet. 2016.

Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype

Muller S.; Acevedo L.; Wang X.; Karim M.Z.; Matta A.; Mehrkens A.; Schaeren S.; Feliciano S.; Jakob M.; Martin I.; Barbero A.; Erwin W.M.. Arthritis Research and Therapy. 2016.

Regenerative potential of tissue engineered nasal chondrocytes in goat articular cartilage defects

Mumme M; Steinitz A; Nuss KM; Klein T; Feliciano S; Kronen P; Jakon M; von Rechenberg B; Martin I; Barbero A; Pelttari K. . 2016.

Regenerative Potential of Tissue-Engineered Nasal Chondrocytes in Goat Articular Cartilage Defects.

Mumme M; Steinitz A; Nuss KM; Klein K; Feliciano S; Kronen P; Jakob M; von Rechenberg B; Martin I; Barbero A; Pelttari K. Tissue engineering. Part A. 2016.

Spontaneous in vivo chondrogenesis of bone marrow-derived mesenchymal progenitor cells by blocking vascular endothelial growth factor signaling

Marsano A.; Medeiros Da Cunha C.M.; Ghanaati S.; Gueven S.; Centola M.; Tsaryk R.; Barbeck M.; Stuedle C.; Barbero A.; Helmrich U.; Schaeren S.; Kirkpatrick J.C.; Banfi A.; Martin I.. Stem Cells Translational Medicine. 2016.

The Survey on Cellular and Engineered Tissue Therapies in Europe in 2013

Martin I.; Ireland H.; Baldomero H.; Dominici M.; Saris D.B.; Passweg J.. Tissue engineering. Part A. 2016.

Three dimensional multi-cellular muscle-like tissue engineering in perfusion-based bioreactors

Cerino G.; Gaudiello E.; Grussenmeyer T.; Melly L.; Massai D.; Banfi A.; Martin I.; Eckstein F.; Grapow M.; Marsano A.. Biotechnology and Bioengineering. 2016.

Animal models for meniscus repair and regeneration

Deponti D.; Giancamillo A.D.; Scotti C.; Peretti G.M.; Martin I.. Journal of Tissue Engineering and Regenerative Medicine. 2015.

An improved cartilage digestion method for research and clinical applications.

Centola M; Tonnarelli B; Hendriks J; van den Doel M; Feliciano S; Papadimitropoulos A; Piccinini E; Geurts J; Martin I; Barbero A. Tissue engineering. Part C, Methods. 2015.

Anti-inflammatory/tissue repair macrophages enhance the cartilage-forming capacity of human bone marrow-derived mesenchymal stromal cells.

Sesia SB; Duhr R; Medeiros da Cunha C; Todorov A; Schaeren S; Padovan E; Spagnoli G; Martin I; Barbero A. Journal of cellular physiology. 2015.

A potential role of homeobox transcription factors in osteoarthritis.

Pelttari K; Barbero A; Martin I. Annals of Translational Medicine. 2015.

Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".

Hirt C; Papadimitropoulos A; Muraro MG; Mele V; Panopoulos E; Cremonesi E; Ivanek R; Schultz-Thater E; Droeser RA; Mengus C; Heberer M; Oertli D; Iezzi G; Zajac P; Eppenberger-Castori S; Tornillo L; Terracciano L; Martin I; Spagnoli GC. Biomaterials. 2015.

Bone-forming capacity of adult human nasal chondrocytes.

Pippenger BE; Ventura M; Pelttari K; Feliciano S; Jaquiery C; Scherberich A; Walboomers XF; Barbero A; Martin I. Journal of cellular and molecular medicine. 2015.

Cartilage graft engineering by co-culturing primary human articular chondrocytes with human bone marrow stromal cells.

Sabatino MA; Santoro R; Gueven S; Jaquiery C; Wendt DJ; Martin I; Moretti M; Barbero A. Journal of Tissue Engineering and Regenerative Medicine. 2015.

Effects of intersyringe processing on adipose tissue and its cellular components: implications in autologous fat grafting.

Osinga R; Menzi NR; Tchang LAH; Caviezel D; Kalbermatten DF; Martin I; Schaefer DJ; Scherberich A; Largo RD. Plastic and reconstructive surgery. 2015.

Engineered decellularized matrices to instruct bone regeneration processes

Papadimitropoulos A.; Scotti C.; Bourgine P.; Scherberich A.; Martin I.. Bone. 2015.

Engraftment of prevascularized, tissue engineered constructs in a novel rabbit segmental bone defect model

Kaempfen A.; Todorov A.; Guven S.; Largo R.D.; Jaquiery C.; Scherberich A.; Martin I.; Schaefer D.J.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2015.

Erratum: Borderud SP, Li Y, Burkhalter JE, Sheffer CE and Ostroff JS. Electronic cigarette use among patients with cancer: Characteristics of electronic cigarette users and their smoking cessation outcomes. Cancer. doi: 10.1002/ cncr.28811.

Manfredonia C; Muraro MG; Hirt C; Mele V; Governa V; Papadimitropoulos A; Däster S; Soysal SD; Droeser RA; Mechera R; Oertli D; Rosso R; Bolli M; Zettl A; Terracciano LM; Spagnoli GC; Martin I; Iezzi G. Cancer. 2015.

Facile fabrication of egg white macroporous sponges for tissue regeneration.

Jalili-Firoozinezhad S; Rajabi-Zeleti S; Mohammadi P; Gaudiello E; Bonakdar S; Solati-Hashjin M; Marsano A; Aghdami N; Scherberich A; Baharvand H; Martin I. Advanced Healthcare Materials. 2015.

Generation and characterization of osteochondral grafts with human nasal chondrocytes.

Barandun M; Iselin LD; Santini F; Pansini M; Scotti C; Baumhoer D; Bieri O; Studler U; Wirz D; Haug M; Jakob M; Schaefer DJ; Martin I; Barbero A. Journal of Orthopaedic Research. 2015.

High-throughput microfluidic platform for 3D cultures of mesenchymal stem cells, towards engineering developmental processes

Occhetta P.; Centola M.; Tonnarelli B.; Redaelli A.; Martin I.; Rasponi M.. Scientific Reports. 2015.

Modular poly(ethylene glycol) matrices for the controlled 3D-localized osteogenic differentiation of mesenchymal stem cells

Metzger S.; Lienemann P.S.; Ghayor C.; Weber W.; Martin I.; Weber F.E.; Ehrbar M.. Advanced Healthcare Materials. 2015.

Novel Perfused Compression Bioreactor System as an in vitro Model to Investigate Fracture Healing.

Hoffmann W; Feliciano S; Martin I; de Wild M; Wendt D. Frontiers in Bioengineering and Biotechnology. 2015.

Tendon healing: an overview of physiology, biology, and pathology of tendon healing and systematic review of state of the art in tendon bioengineering

Muller S.A.; Todorov A.; Heisterbach P.E.; Martin I.; Majewski M.. Knee Surgery, Sports Traumatology, Arthroscopy. 2015.

The survey on cellular and engineered tissue therapies in Europe in 2012.

Martin I; Ireland H; Baldomero H; Passweg J. Tissue engineering. Part A. 2015.

Tissue engineering strategies to study cartilage development, degeneration and regeneration.

Bhattacharjee M; Coburn J; Centola M; Murab S; Barbero A; Kaplan DL; Martin I; Ghosh S. Advanced Drug Delivery Reviews. 2015.

"In vitro" 3D models of tumor-immune system interaction.

Hirt C; Papadimitropoulos A; Mele V; Muraro MG; Mengus C; Iezzi G; Terracciano L; Martin I; Spagnoli GC. Advanced Drug Delivery Reviews. 2014.

Adult human neural crest-derived cells for articular cartilage repair

Pelttari K.; Pippenger B.; Mumme M.; Feliciano S.; Scotti C.; Mainil-Varlet P.; Procino A.; Von Rechenberg B.; Schwamborn T.; Jakob M.; Cillo C.; Barbero A.; Martin I.. Science Translational Medicine. 2014.

Atomic force microscopy to investigate spatial patterns of response to interleukin-1beta in engineered cartilage tissue elasticity

Penuela L.; Wolf F.; Raiteri R.; Wendt D.; Martin I.; Barbero A.. Journal of Biomechanics. 2014.

Bioreactors: Enabling Technologies for Research and Manufacturing

Asnaghi M.A.; Smith T.; Martin I.; Wendt D.. . 2014.

Cell therapy for bone repair: Narrowing the gap between vision and practice

Stegemann J.P.; Verrier S.; Gebhard F.; Laschke M.W.; Martin I.; Simpson H.; Miclau T.. European Cells and Materials. 2014.

Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survival.

Bourgine P; Le Magnen C; Pigeot S; Geurts J; Scherberich A; Martin I. Stem cell research. 2014.

Effect of Purmorphamine on Osteogenic Differentiation of Human Mesenchymal Stem Cells in a Three-Dimensional Dynamic Culture System

Faghihi F.; Papadimitropoulos A.; Martin I.; Eslaminejad M.B.. Cellular and Molecular Bioengineering. 2014.

Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial.

Fulco I; Miot S; Haug MD; Barbero A; Wixmerten A; Feliciano S; Wolf F; Jundt G; Marsano A; Farhadi J; Heberer M; Jakob M; Schaefer DJ; Martin I. The Lancet. 2014.

Engineered tissues as customized organ germs

Martin I.. Tissue engineering. Part A. 2014.

Expansion of human mesenchymal stromal cells from fresh bone marrow in a 3D scaffold-based system under direct perfusion.

Papadimitropoulos A; Piccinini E; Brachat S; Braccini A; Wendt D; Barbero A; Jacobi C; Martin I. PLoS ONE. 2014.

Manufacturing Challenges in Regenerative Medicine

Martin, Ivan; Simmons, Paul J.; Williams, David F.. SCI TRANSL MED. 2014.

Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β.

Mele V; Muraro MG; Calabrese D; Pfaff D; Amatruda N; Amicarella F; Kvinlaug B; Bocelli-Tyndall C; Martin I; Resink TJ; Heberer M; Oertli D; Terracciano L; Spagnoli GC; Iezzi G. International Journal of Cancer. 2014.

Non-adherent mesenchymal progenitors from adipose tissue stromal vascular fraction

Mehrkens A.; Di Maggio N.; Gueven S.; Schaefer D.; Scherberich A.; Banfi A.; Martin I.. Tissue engineering. Part A. 2014.

Osteoblastic differentiation of wharton jelly biopsy specimens and their mesenchymal stromal cells after serum-free culture

Mueller A.A.; Forraz N.; Gueven S.; Degoul G.A.O.; Pagnon-Minot A.; Hartmann D.; Martin I.; Scherberich A.; McGuckin C.. Plastic and reconstructive surgery. 2014.

Osteoinductivity of engineered cartilaginous templates devitalized by inducible apoptosis.

Bourgine PE; Scotti C; Pigeot S; Tchang LA; Todorov A; Martin I. Proceedings of the National Academy of Sciences of the United States of America. 2014.

Rapid prototyped porous nickel–titanium scaffolds as bone substitutes

Hoffmann W.; Bormann T.; Rossi A.; Muller B.; Schumacher R.; Martin I.; de Wild M.; Wendt D.. Journal of Tissue Engineering. 2014.

Re-engineering development to instruct tissue regeneration.

Tonnarelli B; Centola M; Barbero A; Zeller R; Martin I. Current topics in developmental biology. 2014.

TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms.

Scharenberg MA; Pippenger BE; Sack R; Zingg D; Ferralli J; Schenk S; Martin I; Chiquet-Ehrismann R. Journal of cell science. 2014.

The survey on cellular and engineered tissue therapies in Europe in 2011.

Martin I; Baldomero H; Bocelli-Tyndall C; Emmert MY; Hoerstrup SP; Ireland H; Passweg J; Tyndall A. Tissue engineering. Part A. 2014.

Tissue-engineered dermo-epidermal skin grafts prevascularized with adipose-derived cells

Klar A.S.; Guven S.; Biedermann T.; Luginbuhl J.; Bottcher-Haberzeth S.; Meuli-Simmen C.; Meuli M.; Martin I.; Scherberich A.; Reichmann E.. Biomaterials. 2014.

A collagen network phase improves cell seeding of open-pore structure scaffolds under perfusion.

Papadimitropoulos A; Riboldi SA; Tonnarelli B; Piccinini E; Woodruff MA; Hutmacher DW; Martin I. Journal of Tissue Engineering and Regenerative Medicine. 2013.

Engineering of a functional bone organ through endochondral ossification.

Scotti C; Piccinini E; Takizawa H; Todorov A; Bourgine P; Papadimitropoulos A; Barbero A; Manz MG; Martin I. Proceedings of the National Academy of Sciences of the United States of America. 2013.

Meniscus repair and regeneration: Review on current methods and research potential

Scotti C.; Hirschmann M.T.; Antinolfi P.; Martin I.; Peretti G.M.. European Cells and Materials. 2013.

MSCs: Science and trials

Phinney D.G.; Galipeau J.; Krampera M.; Martin I.; Shi Y.; Sensebe L.. Nature Medicine. 2013.

MSCs: science and trials.

Phinney,Donald G; Galipeau,Jacques; Krampera,Mauro; Martin,Ivan; Shi,Yufang; Sensebe,Luc. Nature Medicine. 2013.

Osteogenic graft vascularization and bone resorption by VEGF-expressing human mesenchymal progenitors

Helmrich U.; Di Maggio N.; Guven S.; Groppa E.; Melly L.; Largo R.D.; Heberer M.; Martin I.; Scherberich A.; Banfi A.. Biomaterials. 2013.

Priming 3D cultures of human mesenchymal stromal cells toward cartilage formation via developmental pathways

Centola M.; Tonnarelli B.; Scharen S.; Glaser N.; Barbero A.; Martin I.. Stem Cells and Development. 2013.

Scaffold-based delivery of a clinically relevant anti-angiogenic drug promotes the formation of in vivo stable cartilage

Centola M.; Abbruzzese F.; Scotti C.; Barbero A.; Vadala G.; Denaro V.; Martin I.; Trombetta M.; Rainer A.; Marsano A.. Tissue engineering. Part A. 2013.

The role of 3D structure and protein conformation on the innate andadaptive immune responses to silk-based biomaterials

Bhattacharjee M.; Schultz-Thater E.; Trella E.; Miot S.; Das S.; Loparic M.; Ray A.R.; Martin I.; Spagnoli G.C.; Ghosh S.. Biomaterials. 2013.

Tissue decellularization by activation of programmed cell death

Bourgine P.E.; Pippenger B.E.; Todorov A.; Tchang L.; Martin I.. Biomaterials. 2013.

Toward clinical application of tissue-engineered cartilage.

Fulco I; Largo RD; Miot S; Wixmerten A; Martin I; Schaefer DJ; Haug MD. Facial plastic surgery : FPS. 2013.

Cell-based tissue engineering approaches for disc regeneration

Miot S.; Marsano A.; Martin I.. . 2012.

Developmental engineering of a bone organ with human adult mesenchymal stem cells

Scotti C.; Piccinini E.; Papadimitropoulos A.; Bourgine P.; Todorov A.; Barbero A.; Martin I.. European Cells and Materials. 2012.

EBMT registry of nonhematopoietic stem cells and regenerative therapy (cellular and engineered tissue therapies in Europe)

Baldomero H.; Martin I.; Le Blanc K.; Cornelissen J.; Passweg J.; Niederwieser D.. . 2012.

Effects of a perfusion bioreactor activated novel bone substitute in spine fusion in sheep.

Sørensen JR; Koroma KE; Ding M; Wendt D; Jespersen S; Juhl MV; Theilgaard N; Martin I; Overgaard S. European Spine Journal. 2012.

Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation.

Acharya C; Adesida A; Zajac P; Mumme M; Riesle J; Martin I; Barbero A. Journal of cellular physiology. 2012.

Enhancing the biological performance of synthetic polymeric materials by decoration with engineered, decellularized extracellular matrix.

Sadr N; Pippenger BE; Scherberich A; Wendt D; Mantero S; Martin I; Papadimitropoulos A. Biomaterials. 2012.

Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c.

Di Maggio N; Mehrkens A; Papadimitropoulos A; Schaeren S; Heberer M; Banfi A; Martin I. Stem Cells. 2012.

Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification.

Helmrich U; Marsano A; Melly L; Wolff T; Christ L; Heberer M; Scherberich A; Martin I; Banfi A. Tissue engineering. Part C, Methods. 2012.

IL-1β modulates in vitro remodeling and in vivo bone formation by endochondral primed human bone marrow mesenchymal stromal cells

Mumme M.; Scotti C.; Hoffmann W.; Papadimitropoulos A.; Todorov A.; Gueven S.; Jakob M.; Wendt D.; Martin I.; Barbero A.. European Cells and Materials. 2012.

Influence of in vitro maturation of engineered cartilage on the outcome of osteochondral repair in a goat model

Miot S.; Brehm W.; Dickinson S.; Sims T.; Wixmerten A.; Longinotti C.; Hollander A.P.; Mainil-Varlet P.; Martin I.. European Cells and Materials. 2012.

Influence of in vitro maturation of engineered cartilage on the outcome of osteochondral repair in a goat model.

Miot S; Brehm W; Dickinson S; Sims T; Wixmerten A; Longinotti C; Hollander AP; Mainil-Varlet P; Martin I. European Cells and Materials. 2012.

Interleukin-1β modulates endochondral ossification by human adult bone marrow stromal cells.

Mumme M; Scotti C; Papadimitropoulos A; Todorov A; Hoffmann W; Bocelli-Tyndall C; Jakob M; Wendt D; Martin I; Barbero A. European Cells and Materials. 2012.

Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2

Mehrkens A.; Saxer F.; Guven S.; Hoffmann W.; Muller A.M.; Jakob M.; Weber F.E.; Martin I.; Scherberich A.. European Cells and Materials. 2012.

Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells.

Sensebé L; Tarte K; Galipeau J; Krampera M; Martin I; Phinney DG; Shi Y; MSC Committee of the International Society for Cellular Therapy. Cell Stem Cell. 2012.

On-line monitoring of oxygen as a non-destructive method to quantify cells in engineered 3D tissue constructs.

Santoro R; Krause C; Martin I; Wendt D. Journal of Tissue Engineering and Regenerative Medicine. 2012.

Oriented lamellar silk fibrous scaffolds to drive cartilage matrix orientation: Towards annulus fibrosus tissue engineering

Bhattacharjee M.; Miot S.; Gorecka A.; Singha K.; Loparic M.; Dickinson S.; Das A.; Bhavesh N.S.; Ray A.R.; Martin I.; Ghosh S.. Acta Biomaterialia. 2012.

Perspective on the evolution of cell-based bone tissue engineering strategies

Jakob M.; Saxer F.; Scotti C.; Schreiner S.; Studer P.; Scherberich A.; Heberer M.; Martin I.. European Surgical Research. 2012.

Proposed evolution of bone tissue engineering strategies

Martin I.; Jakob M.; Papadimitropoulos A.; Scotti C.; Wendt D.; Scherberich A.. European Cells and Materials. 2012.

Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1β and low oxygen.

Scotti C; Osmokrovic A; Wolf F; Miot S; Peretti GM; Barbero A; Martin I. Tissue engineering. Part A. 2012.

Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes.

Vonwil D; Trüssel A; Haupt O; Gobaa S; Barbero A; Shastri VP; Martin I. Drug delivery and translational research. 2012.

The survey on cellular and engineered tissue therapies in Europe in 2010.

Martin I; Baldomero H; Bocelli-Tyndall C; Passweg J; Saris D; Tyndall A. Tissue engineering. Part A. 2012.

Tissue engineering for total meniscal substitution: animal study in sheep model--results at 12 months.

Kon E; Filardo G; Tschon M; Fini M; Giavaresi G; Marchesini Reggiani L; Chiari C; Nehrer S; Martin I; Salter DM; Ambrosio L; Marcacci M. Tissue engineering. Part A. 2012.

Validation of an automated procedure to isolate human adipose tissue-derived cells by using the sepax® technology

Guven S.; Karagianni M.; Schwalbe M.; Schreiner S.; Farhadi J.; Bula S.; Bieback K.; Martin I.; Scherberich A.. Tissue Eng Part C Methods. 2012.

A 3D in vitro bone organ model using human progenitor cells

Papadimitropoulos A.; Scherberich A.; Guven S.; Theilgaard N.; Crooijmans H.J.A.; Santini F.; Scheffler K.; Zallone A.; Martin I.. European Cells and Materials. 2011.

Antimicrobial porous surfaces for Ti implants

Hoffmann W.; Koser J.; de Wild M.; Martin I.; Schlottig F.; Jung C.; Pieles U.. European Cells and Materials. 2011.

Autologous tissue-engineered osteochondral graft for talus osteochondral lesions: State-of-the-art and future perspectives

Scotti C.; Leumann A.; Candrian C.; Barbero A.; Croci D.; Schaefer D.J.; Jakob M.; Valderrabano V.; Martin I.. Techniques in Foot and Ankle Surgery. 2011.

Dynamic formation of oriented patches in chondrocyte cell cultures.

Grote MJ; Palumberi V; Wagner B; Barbero A; Martin I. Journal of Mathematical Biology. 2011.

Engineered cartilage maturation regulates cytokine production and interleukin-1β response.

Francioli S; Cavallo C; Grigolo B; Martin I; Barbero A. Clinical Orthopaedics and Related Research. 2011.

Engineering of large osteogenic grafts with rapid engraftment capacity using mesenchymal and endothelial progenitors from human adipose tissue

Guven S.; Mehrkens A.; Saxer F.; Schaefer D.J.; Martinetti R.; Martin I.; Scherberich A.. Biomaterials. 2011.

Ex situ bioengineering of bioartificial endocrine glands: a new frontier in regenerative medicine of soft tissue organs.

Toni R; Tampieri A; Zini N; Strusi V; Sandri M; Dallatana D; Spaletta G; Bassoli E; Gatto A; Ferrari A; Martin I. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2011.

In vitro platforms for tissue engineering: implications for basic research and clinical translation.

Rouwkema J; Gibbs S; Lutolf MP; Martin I; Vunjak-Novakovic G; Malda J. Journal of Tissue Engineering and Regenerative Medicine. 2011.

In vivo chondrogenesis by using anti-angiogenic peptides

Marsano A.; Perugini V.; Centola M.; Guven S.; Banfi A.; Meikle S.T.; Guildford A.L.; Santin M.; Martin I.. . 2011.

Natural/synthetic porous scaffold designs and properties for fibro-cartilaginous tissue engineering

Borzacchiello A.; Gloria A.; Mayol L.; Dickinson S.; Miot S.; Martin I.; Ambrosio L.. JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS. 2011.

Real-time measurements of human chondrocyte heat production during in vitro proliferation.

Santoro R; Braissant O; Müller B; Wirz D; Daniels AU; Martin I; Wendt D. Biotechnology and Bioengineering. 2011.

The influence of the scaffold design on the distribution of adhering cells after perfusion cell seeding.

Melchels FP; Tonnarelli B; Olivares AL; Martin I; Lacroix D; Feijen J; Wendt DJ; Grijpma DW. Biomaterials. 2011.

The survey on cellular and engineered tissue therapies in Europe in 2009.

Martin I; Baldomero H; Bocelli-Tyndall C; Slaper-Cortenbach I; Passweg J; Tyndall A. Tissue engineering. Part A. 2011.

Tissue engineering of annulus fibrosus: Can silk fibres offer a solution for lower back pain?

Bhattacharjee M.; Miot S.; Spagnoli G.; Martin I.; Ghosh S.; Ray A.R.. Proceedings of the Indian National Science Academy. 2011.

Toward modeling the bone marrow niche using scaffold-based 3D culture systems.

Di Maggio N; Piccinini E; Jaworski M; Trumpp A; Wendt DJ; Martin I. Biomaterials. 2011.

Adipose tissue-derived progenitors for engineering osteogenic and vasculogenic grafts

Scherberich A.; Muller A.M.; Schafer D.J.; Banfi A.; Martin I.. Journal of cellular physiology. 2010.

Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages

Strobel S.; Loparic M.; Wendt D.; Schenk A.D.; Candrian C.; Lindberg R.L.P.; Moldovan F.; Barbero A.; Martin I.. Arthritis Research and Therapy. 2010.

An RGD-restricted substrate interface is sufficient for the adhesion, growth and cartilage forming capacity of human chondrocytes.

Vonwil D; Schuler M; Barbero A; Ströbel S; Wendt D; Textor M; Aebi U; Martin I. European Cells and Materials. 2010.

Are ankle chondrocytes from damaged fragments a suitable cell source for cartilage repair?

Candrian C; Miot S; Wolf F; Bonacina E; Dickinson S; Wirz D; Jakob M; Valderrabano V; Barbero A; Martin I. Osteoarthritis and Cartilage. 2010.

A survey on cellular and engineered tissue therapies in europe in 2008.

Martin I; Baldomero H; Tyndall A; Niederwieser D; Gratwohl A. Tissue engineering. Part A. 2010.

A transient 3D-CFD model incorporating biological processes for use in tissue engineering

Kruhne U.; Wendt D.; Martin I.; Juhl M.V.; Clyens S.; Theilgaard N.. Micro and Nanosystems. 2010.

Bioreactor based engineering of large-scale human cartilage grafts for joint resurfacing.

Santoro R; Olivares AL; Brans G; Wirz D; Longinotti C; Lacroix D; Martin I; Wendt D. Biomaterials. 2010.

Bioreactor systems in regenerative medicine

Martin I.; Riboldi S.A.; Wendt D.. . 2010.

Ceramic granules coated with fibrin sealant as a scaffold for perfusion bioreactor in bone tissue engineering

Piccinini E.; Wendt D.; Scherberich A.; Martin I.. European Cells and Materials. 2010.

Ceramic Materials Lead To Underestimated DNA Quantifications: A Method For Reliable Measurements

Piccinini E.; Sadr N.; Martin I.. European Cells and Materials. 2010.

Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy (Nature Nanotechnology (2009) 4 (186-192)

Stolz M.; Gottardi R.; Raiteri R.; Miot S.; Martin I.; Imer R.; Staufer U.; Raducanu A.; Duggelin M.; Baschong W.; Daniels A.U.; Friederich N.F.; Aszodi A.; Aebi U.. Nature Nanotechnology. 2010.

Effect of bone sialoprotein coating of ceramic and synthetic polymer materials on in vitro osteogenic cell differentiation and in vivo bone formation

Schaeren S.; Jaquiery C.; Wolf F.; Papadimitropoulos A.; Barbero A.; Schultz-Thater E.; Heberer M.; Martin I.. Journal of Biomedical Materials Research - Part A. 2010.

Effect of three-dimensional expansion and cell seeding density on the cartilage-forming capacity of human articular chondrocytes in type II collagen sponges.

Francioli SE; Candrian C; Martin K; Heberer M; Martin I; Barbero A. Journal of Biomedical Materials Research - Part A. 2010.

Engineering human cell-based, functionally integrated osteochondral grafts by biological bonding of engineered cartilage tissues to bony scaffolds.

Scotti C; Wirz D; Wolf F; Schaefer DJ; Bürgin V; Daniels AU; Valderrabano V; Candrian C; Jakob M; Martin I; Barbero A. Biomaterials. 2010.

Fibroblast growth factor 2 and platelet-derived growth factor, but not platelet lysate, induce proliferation-dependent, functional class II major histocompatibility complex antigen in human mesenchymal stem cells

Bocelli-Tyndall C.; Zajac P.; Di Maggio N.; Trella E.; Benvenuto F.; Iezzi G.; Scherberich A.; Barbero A.; Schaeren S.; Pistoia V.; Spagnoli G.; Vukcevic M.; Martin I.; Tyndall A.. Arthritis Care and Research. 2010.

Generation of human nasal chondrocytes engineered to express soluble VEGF receptor-2 for cartilage tissue engineering

Marsano A.; Bernegger P.; Helmrich U.; Schaeren S.; Miot S.; Barbero A.; Martin I.; Banfi A.. European Cells and Materials. 2010.

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction.

Miot S; Gianni-Barrera R; Pelttari K; Acharya C; Mainil-Varlet P; Juelke H; Jaquiery C; Candrian C; Barbero A; Martin I. Tissue engineering. Part C, Methods. 2010.

Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite.

Loparic M; Wirz D; Daniels AU; Raiteri R; Vanlandingham MR; Guex G; Martin I; Aebi U; Stolz M. Biophysical Journal. 2010.

Modalities of interaction between human primary chondrocytes and mesenchymal progenitor cells responsible for enhanced in vitro cartilage formation

Acharya C.; Adesida A.; Zajac P.; Schaeren S.; Jakob M.; Riesle J.; Barbero A.; Martin I.. European Cells and Materials. 2010.

Orderly osteochondral regeneration in a sheep model using a novel nano-composite multilayered biomaterial.

Kon E; Delcogliano M; Filardo G; Fini M; Giavaresi G; Francioli S; Martin I; Pressato D; Arcangeli E; Quarto R; Sandri M; Marcacci M. Journal of Orthopaedic Research. 2010.

Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model

Kon E.; Filardo G.; Delcogliano M.; Fini M.; Salamanna F.; Giavaresi G.; Martin I.; Marcacci M.. BMC Musculoskeletal Disorders. 2010.

Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering

Scotti C.; Tonnarelli B.; Papadimitropoulos A.; Scherberich A.; Schaeren S.; Schauerte A.; Lopez-Rios J.; Zeller R.; Barbero A.; Martin I.. Proceedings of the National Academy of Sciences of the United States of America. 2010.

SnapShot: Bioreactors systems in tissue engineering (TE) & regenerative medicine (RM).

Martin I.; Riboldi S.A.; Jakob M.; Wendt D.. Biomaterials. 2010.

SnapShot: Bioreactors systems in tissue engineering (TE) & regenerative medicine (RM).

Martin I; Riboldi SA; Jakob M; Wendt D. Biomaterials. 2010.

Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes

Vonwil D.; Barbero A.; Trussel A.; Haupt O.; Martin I.. European Cells and Materials. 2010.

Towards an intraoperative engineering of osteogenic and vasculogenic grafts from the stromal vascular fraction of human adipose tissue

Muller A.M.; Mehrkens A.; Schafer D.J.; Jaquiery C.; Guven S.; Lehmicke M.; Martinetti R.; Farhadi I.; Jakob M.; Scherberich A.; Martin I.. European Cells and Materials. 2010.

An in vitro model of bone organ starting from progenitor cell populations

Papadimitropoulos A.; Mehrkens A.; Theilgaard N.; Scherberich A.; Martin I.. European Cells and Materials. 2009.

A novel bioreactor with mechanical stimulation for skeletal tissue engineering

Petrovic M.; Mitrakovic D.; Bugarski B.; Vonwil D.; Martin I.; Obradovic B.. Chemical Industry & Chemical Engineering Quarterly. 2009.

A novel implantation technique for engineered osteo-chondral grafts.

Candrian C; Barbero A; Bonacina E; Francioli S; Hirschmann MT; Milz S; Valderrabano V; Heberer M; Martin I; Jakob M. Knee Surgery, Sports Traumatology, Arthroscopy. 2009.

Bioreactor-based roadmap for the translation of tissue engineering strategies into clinical products.

Martin I; Smith T; Wendt D. TRENDS IN BIOTECHNOLOGY. 2009.

Bioreactors in tissue engineering: scientific challenges and clinical perspectives.

Wendt D; Riboldi SA; Cioffi M; Martin I. Advances in Biochemical Engineering-Biotechnology. 2009.

Bioreactor systems in regenerative medicine: From basic science to biomanufacturing

Piccinini E.; Wendt D.; Martin I.. . 2009.

Do we really need cartilage tissue engineering?

Pelttari K.; Wixmerten A.; Martin I.. Swiss Medical Weekly. 2009.

Do we really need cartilage tissue engineering?

Pelttari K; Wixmerten A; Martin I. Swiss Medical Weekly. 2009.

Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy.

Stolz M; Gottardi R; Raiteri R; Miot S; Martin I; Imer R; Staufer U; Raducanu A; Düggelin M; Baschong W; Daniels AU; Friederich NF; Aszodi A; Aebi U. Nature Nanotechnology. 2009.

Intra-individual comparison of human ankle and knee chondrocytes in vitro: relevance for talar cartilage repair.

Candrian C; Bonacina E; Frueh JA; Vonwil D; Dickinson S; Wirz D; Heberer M; Jakob M; Martin I; Barbero A. Osteoarthritis and Cartilage. 2009.

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications.

Montjovent MO; Bocelli-Tyndall C; Scaletta C; Scherberich A; Mark S; Martin I; Applegate LA; Pioletti DP. Tissue engineering. Part A. 2009.

In vivo formation of bone tissue by adult human mesenchymal stem cells depends on the stage of in vitro chondrogenic differentiation

Scotti C.; Papadimitropoulos A.; Tonnarelli B.; Scherberich A.; Barbero A.; Martin I.. European Cells and Materials. 2009.

Platelet lysate as a serum substitute for 2d static and 3d perfusion culture of stromal vascular fraction cells from human adipose tissue

Muller A.M.; Davenport M.; Verrier S.; Droeser R.; Alini M.; Bocelli-Tyndall C.; Schaefer D.J.; Martin I.; Scherberich A.. Tissue engineering. Part A. 2009.

Potential and bottlenecks of bioreactors in 3D cell culture and tissue manufacturing.

Wendt D; Riboldi SA; Cioffi M; Martin I. Advanced Materials. 2009.

Radiographic evaluation of frontal talar edge configuration for osteochondral plug transplantation.

Leumann A; Wiewiorski M; Egelhof T; Rasch H; Magerkurth O; Candrian C; Schaefer DJ; Martin I; Jakob M; Valderrabano V. Clinical anatomy (New York, N.Y.). 2009.

The multipotency of luteinizing granulosa cells collected from mature ovarian follicles

Kossowska-Tomaszczuk K.; De Geyter C.; De Geyter M.; Martin I.; Holzgreve W.; Scherberich A.; Zhang H.. Stem Cells. 2009.

A low percentage of autologous serum can replace bovine serum to engineer human nasal cartilage

Wolf F.; Haug M.; Farhadi J.; Candrian C.; Martin I.; Barbero A.. European Cells and Materials. 2008.

Assessment of nerve damage using a novel ultrasonic device for bone cutting.

Schaeren S; Jaquiéry C; Heberer M; Tolnay M; Vercellotti T; Martin I. Journal of Oral and Maxillofacial Surgery. 2008.

Assessment of TGF-b3 bioactivity for potential bioreactor applications

Vonwil,D; Wendt,D; Stroebel,S; Wallny,HJ; Gygax,D; Heberer,M; Martin,I. . 2008.

Assessment of the stability of TGFβ3 bioactivity for potential bioreactor applications

Vonwil D.; Wendt D.; Strobel S.; Wallny H.J.; Gygax D.; Heberer M.; Martin I.. BIOCHEMICAL ENGINEERING JOURNAL. 2008.

Bioreactor-based tissue engineering strategies

Martin I.; Riboldi S.; Jakob M.; Wendt D.. European Cells and Materials. 2008.

Bioreactors for Tissue Engineering

Wendt D.; Timmins N.; Malda J.; Janssen F.; Ratcliffe A.; Vunjak-Novakovic G.; Martin I.. . 2008.

Bioreactors in tissue engineering: Scientific challenges and clinical prospectives

Martin I.; Riboldi S.; Wendt D.. . 2008.

Cartilage tissue engineering using pre-aggregated human articular chondrocytes.

Wolf F; Candrian C; Wendt D; Farhadi J; Heberer M; Martin I; Barbero A. European Cells and Materials. 2008.

Comparative study of desktop- and synchrotron radiation-based micro computed tomography analyzing cell-seeded scaffolds in tissue engineering of bone

Papadimitropoulos A.; Friess S.; Beckmann F.; Salmon P.; Riboldi S.; Hutmacher D.; Martin I.; Muller B.. . 2008.

Computational evaluation of oxygen and shear stress distributions in 3D perfusion culture systems: macro-scale and micro-structured models.

Cioffi M; Küffer J; Ströbel S; Dubini G; Martin I; Wendt D. Journal of Biomechanics. 2008.

Defining properties of neural crest-derived progenitor cells from the apex of human developing tooth

Degistirici O.; Jaquiery C.; Schonebeck B.; Siemonsmeier J.; Gotz W.; Martin I.; Thie M.. Tissue engineering. Part A. 2008.

Design of graded biomimetic osteochondral composite scaffolds.

Tampieri A; Sandri M; Landi E; Pressato D; Francioli S; Quarto R; Martin I. Biomaterials. 2008.

Do we really need cartilage tissue engineering?

Martin I.; Barbero A.; Jakob M.; Miot S.. European Cells and Materials. 2008.

Effects of fluid flow and calcium phosphate coating on human bone marrow stromal cells cultured in a defined 2D model system.

Scaglione S; Wendt D; Miggino S; Papadimitropoulos A; Fato M; Quarto R; Martin I. Journal of Biomedical Materials Research - Part A. 2008.

Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading

Candrian C.; Vonwil D.; Barbero A.; Bonacina E.; Miot S.; Farhadi J.; Wirz D.; Dickinson S.; Hollander A.; Jakob M.; Li Z.; Alini M.; Heberer M.; Martin I.. Arthritis and Rheumatism. 2008.

Influence of physiological oxygen levels on human chondrocytes cultured in porous PEGT/PBT scaffolds under perfusion

Tonnarelli B.; Stroebel S.; Martin I.; Wendt D.. . 2008.

Lumican inhibits collagen deposition in tissue engineered cartilage

Kafienah W.; Cheung F.L.; Sims T.; Martin I.; Miot S.; Ruhland C.V.; Roughley P.J.; Hollander A.P.. Matrix biology : journal of the International Society for Matrix Biology. 2008.

New dimensions in tumor immunology: what does 3D culture reveal?

Feder-Mengus C.; Ghosh S.; Reschner A.; Martin I.; Spagnoli G.C.. Trends in molecular medicine. 2008.

Spatial and temporal patterns of bone formation in ectopically pre-fabricated, autologous cell-based engineered bone flaps in rabbits.

Scheufler O; Schaefer DJ; Jaquiery C; Braccini A; Wendt DJ; Gasser JA; Galli R; Pierer G; Heberer M; Martin I. Journal of cellular and molecular medicine. 2008.

The presence of a collagen matrix among the fibers of fused deposition-modeled scaffolds improves their performances upon perfusion seeding

Riboldi S.A.; Wendt D.; Hutmacher D.W.; Martin I.. . 2008.

Tissue engineering for total meniscal substitution: Animal study in sheep model

Kon E.; Chiari C.; Marcacci M.; Delcogliano M.; Salter D.M.; Martin I.; Ambrosio L.; Fini M.; Tschon M.; Tognana E.; Plasenzotti R.; Nehrer S.. Tissue engineering. Part A. 2008.

Weak functional coupling of the melanocortin-1 receptor expressed in human adipocytes.

Hoch M; Hirzel E; Lindinger P; Eberle AN; Linscheid P; Martin I; Peters T; Peterli R. Journal of Receptors and Signal Transduction. 2008.

Bioreactor-based engineering of osteoinductive grafts

Martin I.; Braccini A.; Jakob M.; Jaquiery C.; Scharen S.; Heberer M.; Wendt D.. European Cells and Materials. 2007.

Bone marrow derived mesenchymal stem cells isolated from patients with diabetes mellitus type 1 are able to induce a pancreatic endocrine genes in vitro.

Sebok D; Eberhardt M; Barbero A; Linscheid P; Timper K; Martin I; Keller U; Muller B; Zulewski H. Journal of stem cells & regenerative medicine. 2007.

Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro.

Bocelli-Tyndall C; Bracci L; Spagnoli G; Braccini A; Bouchenaki M; Ceredig R; Pistoia V; Martin I; Tyndall A. Rheumatology (United Kingdom). 2007.

Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes

Marsano A.; Millward-Sadler S.J.; Salter D.M.; Adesida A.; Hardingham T.; Tognana E.; Kon E.; Chiari-Grisar C.; Nehrer S.; Jakob M.; Martin I.. Osteoarthritis and Cartilage. 2007.

Expansion of adult human chondrocytes on an extendable surface: A strategy to reduce passageing-related dedifferentiation

Vonwil D.; Barbero A.; Quinn T.; Martin I.. European Cells and Materials. 2007.

Generation of osteogenic and vasculogenic implants by perfusion culture of adipose tissue-derived cells

Muller A.M.; Galli R.; Jaquiery C.; Farhadi J.; Martin I.; Scherberich A.. European Cells and Materials. 2007.

Growth factors for clinical-scale expansion of human articular chondrocytes: relevance for automated bioreactor systems.

Francioli SE; Martin I; Sie CP; Hagg R; Tommasini R; Candrian C; Heberer M; Barbero A. Tissue engineering. 2007.

Human articular chondrocytes culture.

Barbero A.; Martin I.. Methods in molecular medicine. 2007.

Identification of markers to characterize and sort human articular chondrocytes with enhanced in vitro chondrogenic capacity.

Grogan SP; Barbero A; Diaz-Romero J; Cleton-Jansen AM; Soeder S; Whiteside R; Hogendoorn PC; Farhadi J; Aigner T; Martin I; Mainil-Varlet P. Arthritis and Rheumatism. 2007.

Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005.

Tyndall A; Walker UA; Cope A; Dazzi F; De Bari C; Fibbe W; Guiducci S; Jones S; Jorgensen C; Le Blanc K; Luyten F; McGonagle D; Martin I; Bocelli-Tyndall C; Pennesi G; Pistoia V; Pitzalis C; Uccelli A; Wulffraat N; Feldmann M. Arthritis Research and Therapy. 2007.

Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes

Feder-Mengus C.; Ghosh S.; Weber W.P.; Wyler S.; Zajac P.; Terracciano L.; Oertli D.; Heberer M.; Martin I.; Spagnoli G.C.; Reschner A.. British Journal of Cancer. 2007.

Nanoscale engineering of biomaterial surfaces

Lipski, Anna Marie; Jaquiery, Claude; Choi, Hoon; Eberli, Daniel; Stevens, Molly; Martin, Ivan; Chen, I. -Wei; Shastri, Venkatram Prasad. Advanced Materials. 2007.

Osteochondral tissue engineering.

Martin I; Miot S; Barbero A; Jakob M; Wendt D. Journal of Biomechanics. 2007.

Surface-induced modulation of human mesenchymal progenitor cells. An in vitro model for early implant integration.

Baschong W.; Jaquiery C.; Martin I.; Lambrecht T.J.. Schweizer Monatsschrift für Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia / SSO. 2007.

The osteogenicity of implanted engineered bone constructs is related to the density of clonogenic bone marrow stromal cells

Braccini A.; Wendt D.; Farhadi J.; Schaeren S.; Heberer M.; Martin I.. Journal of Tissue Engineering and Regenerative Medicine. 2007.

The stand-alone T-CUP bioreactor system: Towards the automated manufacture of engineered bone grafts

Riboldi S.A.; Jakob M.; Frueh J.A.; Cueni D.; Pereira P.; Scherberich A.; Martin I.. European Cells and Materials. 2007.

Three-dimensional cell culture and tissue engineering in a T-CUP (tissue culture under perfusion).

Timmins NE; Scherberich A; Früh JA; Heberer M; Martin I; Jakob M. Tissue engineering. 2007.

Three dimensional micro-structure of scaffolds for tissue replacement

Gurel S.; Braccini A.; Martin I.; Beckmann F.; Muller B.. European Cells and Materials. 2007.

Three-dimensional perfusion culture of human adipose tissue-derived endothelial and osteoblastic progenitors generates osteogenic constructs with intrinsic vascularization capacity

Scherberich A.; Galli R.; Jaquiery C.; Farhadi J.; Martin I.. Stem Cells. 2007.

Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: A role for T-cadherin in tumor angiogenesis

Ghosh S.; Joshi M.B.; Ivanov D.; Feder-Mengus C.; Spagnoli G.C.; Martin I.; Erne P.; Resink T.J.. FEBS Letters. 2007.

[Engineering 3D cartilage grafts].

Martin I. Praxis. 2006.

Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes.

Laschke MW; Harder Y; Amon M; Martin I; Farhadi J; Ring A; Torio-Padron N; Schramm R; Rücker M; Junker D; Häufel JM; Carvalho C; Heberer M; Germann G; Vollmar B; Menger MD. Tissue engineering. 2006.

Bioreactors for cartilage tissue engineering

Martin I.; Stroebel S.; Marsano A.; Jakob M.; Wendt D.. European Cells and Materials. 2006.

Bi-zonal cartilaginous tissues engineered in a rotary cell culture system

Marsano A.; Wendt D.; Quinn T.M.; Sims T.J.; Farhadi J.; Jakob M.; Heberer M.; Martin I.. Biorheology. 2006.

Bi-zonal cartilaginous tissues engineered in a rotary cell culture system.

Marsano A; Wendt D; Quinn TM; Sims TJ; Farhadi J; Jakob M; Heberer M; Martin I. Biorheology. 2006.

Bone and cartilage tissue engineering for facial reconstructive surgery.

Farhadi J; Jaquiery C; Haug M; Pierer G; Zeilhofer HF; Martin I. IEEE ENG MED BIOL. 2006.

Cartilage tissue engineering by expanded goat articular chondrocytes.

Miot S; Scandiucci de Freitas P; Wirz D; Daniels AU; Sims TJ; Hollander AP; Mainil-Varlet P; Heberer M; Martin I. Journal of Orthopaedic Research. 2006.

Cartilage tissue engineering for degenerative joint disease.

Nesic D; Whiteside R; Brittberg M; Wendt D; Martin I; Mainil-Varlet P. Advanced Drug Delivery Reviews. 2006.

Engineering of osteoinductive grafts by isolation and expansion of ovine bone marrow stromal cells directly on 3D ceramic scaffolds.

Scaglione S; Braccini A; Wendt D; Jaquiery C; Beltrame F; Quarto R; Martin I. Biotechnology and Bioengineering. 2006.

Expansion on specific substrates regulates the phenotype and differentiation capacity of human articular chondrocytes

Barbero A.; Grogan S.P.; Mainil-Varlet P.; Martin I.. Journal of cellular biochemistry. 2006.

Human articular chondrocytes suppress in vitro proliferation of anti-CD3 activated peripheral blood mononuclear cells

Bocelli-Tyndall C.; Barbero A.; Candrian C.; Ceredig R.; Tyndall A.; Martin I.. Journal of cellular physiology. 2006.

Local compressive and tensile stiffness measured in tissues with regular patterns of hyaline-fibrocartilage regions

Marsano A.; Wendt D.; Raiteri R.; Gottardi R.; Dickinson S.; Hollander A.P.; Wirz D.; Daniels A.U.; Quinn T.M.; Stolz M.; Martin I.. European Cells and Materials. 2006.

Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface

Mahmood T.A.; Miot S.; Frank O.; Martin I.; Riesle J.; Langer R.; van Blitterswijk C.A.. Biomacromolecules. 2006.

Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets.

Eberhardt M; Salmon P; von Mach MA; Hengstler JG; Brulport M; Linscheid P; Seboek D; Oberholzer J; Barbero A; Martin I; Müller B; Trono D; Zulewski H. Biochemical and Biophysical Research Communications. 2006.

Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery.

Farhadi J; Fulco I; Miot S; Wirz D; Haug M; Dickinson SC; Hollander AP; Daniels AU; Pierer G; Heberer M; Martin I. Annals of Surgery. 2006.

Response of adult human articular chondrocytes to a non-fouling RGD-peptide modified surface

Vonwil D.; Schuler M.; Barbero A.; Strobel S.; Textor M.; Aebi U.; Martin I.. European Cells and Materials. 2006.

The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification

Woodfield T.B.F.; Miot S.; Martin I.; Van Blitterswijk C.A.; Riesle J.. Biomaterials. 2006.

Towards tissue engineering of meniscus substitutes: selection of cell source and culture environment.

Marsano A; Vunjak-Novakovic G; Martin I. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2006.

Uniform tissues engineered by seeding and culturing cells in 3D scaffolds under perfusion at defined oxygen tensions

Wendt D.; Stroebel S.; Jakob M.; John G.T.; Martin I.. Biorheology. 2006.

Uniform tissues engineered by seeding and culturing cells in 3D scaffolds under perfusion at defined oxygen tensions.

Wendt D; Stroebel S; Jakob M; John GT; Martin I. Biorheology. 2006.

Use of hydrodynamic forces to engineer cartilaginous tissues resembling the non-uniform structure and function of meniscus.

Marsano A; Wendt D; Raiteri R; Gottardi R; Stolz M; Wirz D; Daniels AU; Salter D; Jakob M; Quinn TM; Martin I. Biomaterials. 2006.

Visual histological grading system for the evaluation of in vitro-generated neocartilage.

Grogan SP; Barbero A; Winkelmann V; Rieser F; Fitzsimmons JS; O'Driscoll S; Martin I; Mainil-Varlet P. Tissue engineering. 2006.

Bioreactor-based engineering of osteochondral grafts: From model systems to tissue manufacturing

Wendt D.; Jakob M.; Martin I.. JOURNAL OF BIOSCIENCE AND BIOENGINEERING. 2005.

British society for matrix biology autumn meeting

Sudre L.; Cheung F.; Kevorkian L.; Young D.A.; Darrah C.; Donell S.T.; Shepstone L.; Porter S.; Brockbank S.; Edwards D.R.; Parker A.E.; Clark I.M.; Boubriak O.A.; Urban J.P.G.; Cui Z.; Tew S.R.; Li Y.; Tweats L.M.; Hawkins R.E.; Hardingham T.E.; Green D.; Partridge K.A.; Leveque I.; Mann S.; Oreffo R.O.C.; Ball S.G.; Kielty C.M.; Qin M.; Tai G.; Polak J.M.; Bishop A.E.; Stolzing A.; Scutt A.; Screen H.R.C.; Shelton J.C.; Bader D.L.; Lee D.A.; Hall A.; Hayes A.; Brown L.; Tubo R.; Caterson B.; Blain E.J.; Gilbert S.J.; Duance V.C.; Davies L.; Blain E.; Duance V.; Shengda Z.; Wu M.-H.; Xu X.; Heywood H.K.; Sims T.; Miot S.; Martin I.; Roughley P.J.; Soranzo C.; Pavesio A.; Hollander A.P.; Yang X.; Webb D.; Blaker J.; Maquet V.; Boccaccini A.R.; Cooper C.; Eves P.; Beck A.J.; Shard A.G.; Gawkrodger D.J.; Mac Neil S.; Rajpar M.H.; Kadler K.E.; Thornton D.J.; Briggs M.D.; Boot-Handford R.P.; Ellis M.J.; Tai C.-C.; Perera S.; Chaudhuri J.B.; Callender P.; Mason D.J.; Colley H.; Mc Arthur S.; Scutt A.; Mirmalek-Sani S.H.; Roach H.I.; Hanley N.A.; Wilson D.I.; MacIntosh A.C.; Crawford A.; Hatton P.V.; Wallis G.; Shah R.; Knowles J.C.; Hunt N.P.; Lewis M.P.; Rippon H.J.; Ali B.E.; De Bank P.A.; Kellam B.; Shakesheff K.M.; Comerford E.J.; Tarlton J.F.; Wales A.; Bailey A.J.; Innes J.F.; Olivier V.; Xie Y.; Descamps M.; Hivart P.; Lu J.; Hardouin P.; Anderson V.; Spiller D.G.; Vaughan-Thomas A.; Eissa S.Z.S.; Faram T.; Birch H.L.; Zeugolis D.; Paul G.; Attenburrow G.; Bhadal N.; Whawell S.A.; Worrall L.K.; Rose F.R.A.J.; Bradshaw T.D.; Stevens M.F.G.; Chuo C.B.; Wiseman M.A.; Phillips J.B.; Brown R.A.; Harrison C.A.; Gossiel F.; Bullock A.J.; Blumsohn A.; Li Z.; Derham B.; Gaissmaier C.; Fritz J.; Krackhardt T.; Flesch I.; Aicher W.K.; Ashammakhi N.; Liu K.-K.; Yang Y.; Ahearne M.; Then K.; El Haj A.; Cheung I.; Wright T.C.; Kostyuk O.; Baria K.E.; Chowdhury T.T.; Sharma A.M.; Bomzon Z.; Kimmel E.; Knight M.M.; Dickinson S.; Pittarello L.; Fish R.S.; Ralphs J.R.; Farjanel J.; Seve S.; Borel A.; Sommer P.; Hulmes D.J.S.; Whiting C.V.; Dalton S.J.; Mitchell D.C.; Kafienah W.; Mistry S.; Hollander A.; Cartmell S.; Magnay J.; Dobson J.; Appleby R.N.; Salter D.M.; Scutt N.; Rolf C.G.; Barry J.J.A.; Nazhat S.N.; Scotchford C.A.; Howdle S.M.; Roberts S.; Gargiulo B.; Evans E.H.; Menage J.; Johnson W.E.B.; Eisenstein S.; Richardson J.B.; Stenfeldt C.; Avery N.C.; Tidswell H.; Crabtree J.; Frazer A.; Fraser S.; Wong M.; Beckett K.; Grobbelaar A.; Mudera V.; Bax D.V.; Cain S.A.; Humphries M.J.; Lomas A.; Oldershaw R.; Murdoch A.; Brennan K.; Redman S.; Haughton L.; Dowthwaite G.; Williams A.; Archer C.W.; Esfandiari E.; Stokes C.R.; Cox T.M.; Evans M.J.; Bailey M.; Hayman A.R.; Day M.J.; Williams R.; Evans D.; Adesida A.; Millwards-Sadler J.; Salter D.; Smith R.; Korda M.; Porter R.; Kalia P.; Wiseman M.; Blunn G.; Goodship A.; McClumpha A.; Horrocks M.; Pabbruwe M.B.; Du X.; Stewart K.; Suciati T.; Lakey R.L.; Pennington C.J.; Cawston T.E.; Palmer L.; Tasman C.; Clare M.; Gidley J.; Sandy J.; Mansell J.; Ellis T.; Burger F.; Lauder R.; Khan I.; Smith M.. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 2005.

Cartilage engineering and microgravity

Toffanin R.; Bader A.; Cogoli A.; Carda C.; Fantazzini P.; Garrido L.; Gomez S.; Hall L.; Martin I.; Murano E.; Poncelet D.; Portner R.. . 2005.

Characterization of transcript levels for matrix molecules and proteases in ruptured human anterior cruciate ligaments

Bramono D.S.; Richmond J.C.; Weitzel P.P.; Chernoff H.; Martin I.; Volloch V.; Jakuba C.M.; Diaz F.; Gandhi J.S.; Kaplan D.L.; Altman G.H.. Connective tissue research. 2005.

Culture of melanoma cells in 3-dimensional architectures results in impaired immunorecognition by cytotoxic T lymphocytes specific for Melan-A/MART-1 tumor-associated antigen.

Ghosh S; Rosenthal R; Zajac P; Weber WP; Oertli D; Heberer M; Martin I; Spagnoli GC; Reschner A. Annals of Surgery. 2005.

Differentiation-dependent up-regulation of BMP-2, TGF-beta1, and VEGF expression by FGF-2 in human bone marrow stromal cells.

Farhadi J; Jaquiery C; Barbero A; Jakob M; Schaeren S; Pierer G; Heberer M; Martin I. Plastic and reconstructive surgery. 2005.

Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells

Von Knoch F.; Jaquiery C.; Kowalsky M.; Schaeren S.; Alabre C.; Martin I.; Rubash H.E.; Shanbhag A.S.. Biomaterials. 2005.

Effects of in vitro preculture on in vivo development of human engineered cartilage in an ectopic model

Moretti M.; Wendt D.; Dickinson S.C.; Sims T.J.; Hollander A.P.; Kelly D.J.; Prendergast P.J.; Heberer M.; Martin I.. Tissue engineering. 2005.

Effects of scaffold composition and architecture on human nasal chondrocyte redifferentiation and cartilaginous matrix deposition

Miot S.; Woodfield T.; Daniels A.U.; Suetterlin R.; Peterschmitt I.; Heberer M.; Van Blitterswijk C.A.; Riesle J.; Martin I.. Biomaterials. 2005.

Experimental and mathematical study of the influence of growth factors on the growth kinetics of adult human articular chondrocytes.

Barbero A; Palumberi V; Wagner B; Sader R; Grote MJ; Martin I. Journal of cellular physiology. 2005.

In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering

Mauney J.R.; Jaquiery C.; Volloch V.; Heberer M.; Martin I.; Kaplan D.L.. Biomaterials. 2005.

In vitro osteogenic differentiation and in vivo bone-forming capacity of human isogenic jaw periosteal cells and bone marrow stromal cells.

Jaquiéry C; Schaeren S; Farhadi J; Mainil-Varlet P; Kunz C; Zeilhofer HF; Heberer M; Martin I. Annals of Surgery. 2005.

Structural characterization and reliable biomechanical assessment of integrative cartilage repair.

Moretti M; Wendt D; Schaefer D; Jakob M; Hunziker EB; Heberer M; Martin I. Journal of Biomechanics. 2005.

Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study

Ghosh S.; Spagnoli G.C.; Martin I.; Ploegert S.; Demougin P.; Heberer M.; Reschner A.. Journal of cellular physiology. 2005.

Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts.

Braccini A; Wendt D; Jaquiery C; Jakob M; Heberer M; Kenins L; Wodnar-Filipowicz A; Quarto R; Martin I. Stem Cells. 2005.

[Engineering and characterization of functional osteochondral replacement tissue].

Schäfer D; Seidel J; Martin I; Jundt G; Heberer M; Grozinsky A; Vunjak-Novakovic G; Freed L. Orthopade. 2004.

Age related changes in human articular chondrocyte yield, proliferation and post-expansion chondrogenic capacity.

Barbero A; Grogan S; Schäfer D; Heberer M; Mainil-Varlet P; Martin I. Osteoarthritis and Cartilage. 2004.

Articular chondrocyte attachment and gene expression can be modulated by polymeric substrates for cell transplantation

Mahmood T.A.; Miot S.; Frank O.; Van Blitterswijk C.A.; Langer R.; Martin I.; Riesle J.. . 2004.

Bioreactor culture techniques for cartilage-tissue engineering.

Lee D.A.; Martin I.. Methods in Molecular Biology. 2004.

Cell yield, proliferation, and postexpansion differentiation capacity of human ear, nasal, and rib chondrocytes

Tay A.G.; Farhadi J.; Suetterlin R.; Pierer G.; Heberer M.; Martin I.. Tissue engineering. 2004.

Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins.

Jakob M; Démarteau O; Suetterlin R; Heberer M; Martin I. Rheumatology (United Kingdom). 2004.

Effects of cyclic longitudinal mechanical strain and dexamethasone on osteogenic differentiation of human bone marrow stromal cells

Jagodzinski M.; Drescher M.; Zeichen J.; Hankemeier S.; Krettek C.; Bosch U.; Van Griensven M.; Martin I.; Evans C.. European Cells and Materials. 2004.

Engineering and characterization of functional osteochondral repair tissue

Schafer D.; Seidel J.; Martin I.; Jundt G.; Heberer M.; Grozinsky A.; Vunjak-Novakovic G.; Freed L.. Orthopade. 2004.

FGF-2 enhances TGF-beta1-induced periosteal chondrogenesis.

Stevens MM; Marini RP; Martin I; Langer R; Prasad Shastri V. Journal of Orthopaedic Research. 2004.

Gas plasma treatment and PEGT/PBT substrate composition affect human chondrocyte attachment and redifferentiation capacity

Woodfield T.; Miot S.; Martin I.; Van Blitterswijk C.A.; Riesle J.. . 2004.

Human chondrocyte redifferentiation and cartilage tissue formation capacity is regulated by architecture and composition of porous PEGT/PBT scaffolds

Woodfield T.; Miot S.; Van Blitterswijk C.A.; Riesle J.; Martin I.. . 2004.

Lubricin reduces cartilage-cartilage integration

Schaefer D.B.; Wendt D.; Moretti M.; Jakob M.; Jay G.D.; Heberer M.; Martin I.. Biorheology. 2004.

Lubricin reduces cartilage--cartilage integration.

Schaefer DB; Wendt D; Moretti M; Jakob M; Jay GD; Heberer M; Martin I. Biorheology. 2004.

Real-time quantitative rt-PCR assays.

Martin I.; Frank O.. Methods in Molecular Biology. 2004.

The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells.

Heim M; Frank O; Kampmann G; Sochocky N; Pennimpede T; Fuchs P; Hunziker W; Weber P; Martin I; Bendik I. Endocrinology. 2004.

The role of bioreactors in tissue engineering.

Martin I; Wendt D; Heberer M. TRENDS IN BIOTECHNOLOGY. 2004.

Bioreactor culture techniques for cartilage tissue engineering

Lee,D.A.; Martin,I. . 2003.

Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes.

Démarteau O; Wendt D; Braccini A; Jakob M; Schäfer D; Heberer M; Martin I. Biochemical and Biophysical Research Communications. 2003.

Enzymatic digestion of adult human articular cartilage yields a small fraction of the total available cells

Jakob M.; Demarteau O.; Schafer D.; Stumm M.; Heberer M.; Martin I.. Connective tissue research. 2003.

Enzymatic digestion of adult human articular cartilage yields a small fraction of the total available cells.

Jakob M; Démarteau O; Schäfer D; Stumm M; Heberer M; Martin I. Connective tissue research. 2003.

Human jaw periosteal cells display reduced and delayed in vitro osteogenic differentiation as compared to bone marrow stromal cells

Jaquiery C.; Barbero A.; Kunz C.; Zeilhofer H.-F.; Heberer M.; Martin I.. European Cells and Materials. 2003.

Oscillating perfusion of cell suspensions through three-dimensional scaffolds enhances cell seeding efficiency and uniformity.

Wendt D; Marsano A; Jakob M; Heberer M; Martin I. Biotechnology and Bioengineering. 2003.

Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes

Barbero A.; Ploegert S.; Heberer M.; Martin I.. Arthritis and Rheumatism. 2003.

Real-time quantitative RT-PCR assays

Martin,I; Frank,O. . 2003.

Advanced bioreactor with controlled application of multi-dimensional strain for tissue engineering

Altman G.H.; Lu H.H.; Horan R.L.; Calabro T.; Ryder D.; Kaplan D.L.; Stark P.; Martin I.; Richmond J.C.; Vunjak-Novakovic G.. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 2002.

Bioerodible polypyrrole

Zelikin A.; Shastri V.; Lynn D.; Farhadi J.; Martin I.; Langer R.. Materials Research Society Symposium - Proceedings. 2002.

Bioreactor studies of native and tissue engineered cartilage

Vunjak-Novakovic G.; Obradovic B.; Martin I.; Freed L.E.. Biorheology. 2002.

Bioreactor studies of native and tissue engineered cartilage.

Vunjak-Novakovic G; Obradovic B; Martin I; Freed LE. Biorheology. 2002.

Cell differentiation by mechanical stress.

Altman G.H.; Horan R.L.; Martin I.; Farhadi J.; Stark P.R.; Volloch V.; Richmond J.C.; Vunjak-Novakovic G.; Kaplan D.L.. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2002.

Development and validation of a bioreactor for physical stimulation of engineered cartilage

Demarteau O.; Jakob M.; Schafer D.; Heberer M.; Martin I.. Biorheology. 2002.

Erodible conducting polymers for potential biomedical applications

Zelikin A.N.; Lynn D.M.; Farhadi J.; Martin I.; Shastri V.; Langer R.. Angewandte Chemie - International Edition. 2002.

Fluorescence microscopy imaging of bone for automated histomorphometry.

Martin I; Mastrogiacomo M; De Leo G; Muraglia A; Beltrame F; Cancedda R; Quarto R. Tissue engineering. 2002.

I bioreattori

Martin,I. . 2002.

Modulation of chondrocyte phenotype to generate implantable grafts

Martin I.; Demarteau O.; Wendt D.; Jakob M.; Schafer D.; Heberer M.. European Cells and Materials. 2002.

Plasticity of human de-differentiated chondrocytes

Barbero A.; Ploegert S.; Heberer M.; Martin I.. European Cells and Materials. 2002.

Real-time quantitative RT-PCR analysis of human bone marrow stromal cells during osteogenic differentiation in vitro.

Frank O; Heim M; Jakob M; Barbero A; Schäfer D; Bendik I; Dick W; Heberer M; Martin I. Journal of cellular biochemistry. 2002.

Recent advances in cartilage tissue engineering: From the choice of cell sources to the use of bioreactors

Martin, I; Demarteau, O; Braccini, A. JSME International Journal. 2002.

Recent advances in cartilage tissue engineering: From the choice of cell sources to the use of bioreactors

Martin I.; Demarteau O.; Braccini A.. JSME International Journal, Series C: Mechanical Systems, Machine Elements and Manufacturing. 2002.

Silk matrix for tissue engineered anterior cruciate ligaments.

Altman GH; Horan RL; Lu HH; Moreau J; Martin I; Richmond JC; Kaplan DL. Biomaterials. 2002.

Three-dimensional tissue engineering of hyaline cartilage: comparison of adult nasal and articular chondrocytes.

Kafienah W; Jakob M; Démarteau O; Frazer A; Barker MD; Martin I; Hollander AP. Tissue engineering. 2002.

Tissue-engineered composites for the repair of large osteochondral defects.

Schaefer D; Martin I; Jundt G; Seidel J; Heberer M; Grodzinsky A; Bergin I; Vunjak-Novakovic G; Freed LE. Arthritis and Rheumatism. 2002.

Tissue engineering by cell transplantation.

Shastri PV; Martin I. Ernst Schering Res Found Workshop. 2002.

Towards functional cartilage equivalents: Bioreactor cultivation of cell-polymer constructs

Obradovic B.; Martin I.; Freed L.E.; Vunjak-Novakovic G.. . 2002.

Bioreactor studies of natural and tissue engineered cartilage.

Obradovic B; Martin I; Freed LE; Vunjak-Novakovic G. Ortopedia, traumatologia, rehabilitacja. 2001.

Enhanced cartilage tissue engineering by sequential exposure of chondrocytes to FGF-2 during 2D expansion and BMP-2 during 3D cultivation

Martin I.; Suetterlin R.; Baschong W.; Heberer M.; Vunjak-Novakovic G.; Freed L.E.. Journal of cellular biochemistry. 2001.

Integration of engineered cartilage.

Obradovic B; Martin I; Padera RF; Treppo S; Freed LE; Vunjak-Novakovic G. Journal of Orthopaedic Research. 2001.

Low-density caveolae-like membrane from Xenopus laevis oocytes is enriched in ras

Martin I.; Suetterlin R.; Baschong W.; Heberer M.; Vunjak-Novakovic G.; Freed L.E.. Journal of cellular biochemistry. 2001.

Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints.

Martin I; Jakob M; Schäfer D; Dick W; Spagnoli G; Heberer M. Osteoarthritis and Cartilage. 2001.

Selective differentiation of mammalian bone marrow stromal cells cultured on three-dimensional polymer foams.

Martin I; Shastri VP; Padera RF; Yang J; Mackay AJ; Langer R; Vunjak-Novakovic G; Freed LE. J BIOMED MATER RES. 2001.

Specific growth factors during the expansion and redifferentiation of adult human articular chondrocytes enhance chondrogenesis and cartilaginous tissue formation in vitro.

Jakob M; Démarteau O; Schäfer D; Hintermann B; Dick W; Heberer M; Martin I. Journal of cellular biochemistry. 2001.

Use of nasal chondrocytes in the tissue engineering of articular cartilage

Kafienah W.; Hollander A.P.; Martin I.; Demarteau O.; Frazer A.; Barker M.. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 2001.

Was gibt es Neues in der Chirurgischen Forschung? Speziell: Tissue Engineering

Heberer,M; Martin,I. . 2001.

Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones.

Kon E; Muraglia A; Corsi A; Bianco P; Marcacci M; Martin I; Boyde A; Ruspantini I; Chistolini P; Rocca M; Giardino R; Cancedda R; Quarto R. J BIOMED MATER RES. 2000.

In vitro generation of osteochondral composites.

Schaefer D; Martin I; Shastri P; Padera RF; Langer R; Freed LE; Vunjak-Novakovic G. Biomaterials. 2000.

Macroporous polymer foams by hydrocarbon templating.

Shastri VP; Martin I; Langer R. Proceedings of the National Academy of Sciences of the United States of America. 2000.

Modulation of the mechanical properties of tissue engineered cartilage.

Martin I; Obradovic B; Treppo S; Grodzinsky AJ; Langer R; Freed LE; Vunjak-Novakovic G. Biorheology. 2000.

Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage.

Vunjak-Novakovic G; Martin I; Obradovic B; Treppo S; Grodzinsky AJ; Langer R; Freed LE. Journal of Orthopaedic Research. 1999.

Frontiers in tissue engineering. In vitro modulation of chondrogenesis.

Freed LE; Martin I; Vunjak-Novakovic G. Clinical Orthopaedics and Related Research. 1999.

Mammalian chondrocytes expanded in the presence of fibroblast growth factor 2 maintain the ability to differentiate and regenerate three-dimensional cartilaginous tissue.

Martin I; Vunjak-Novakovic G; Yang J; Langer R; Freed LE. Experimental Cell Research. 1999.

Method for quantitative analysis of glycosaminoglycan distribution in cultured natural and engineered cartilage.

Martin I; Obradovic B; Freed LE; Vunjak-Novakovic G. Annals of Biomedical Engineering. 1999.

Reconstruction of extensive long-bone defects in sheep using porous hydroxyapatite sponges.

Marcacci M; Kon E; Zaffagnini S; Giardino R; Rocca M; Corsi A; Benvenuti A; Bianco P; Quarto R; Martin I; Muraglia A; Cancedda R. Calcified Tissue International. 1999.

A nude mouse model for human bone formation in unloaded conditions.

Muraglia A; Martin I; Cancedda R; Quarto R. Bone. 1998.

Chondrogenesis in a cell-polymer-bioreactor system.

Freed LE; Hollander AP; Martin I; Barry JR; Langer R; Vunjak-Novakovic G. Experimental Cell Research. 1998.

Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering.

Vunjak-Novakovic G; Obradovic B; Martin I; Bursac PM; Langer R; Freed LE. BIOTECHNOLOGY PROGRESS. 1998.

In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bone-like tissues.

Martin I; Padera RF; Vunjak-Novakovic G; Freed LE. Journal of Orthopaedic Research. 1998.

Prefabricated engineered bone flaps: an experimental model of tissue reconstruction in plastic surgery.

Casabona F; Martin I; Muraglia A; Berrino P; Santi P; Cancedda R; Quarto R. Plastic and reconstructive surgery. 1998.

2D/3D image analysis as a tool for tissue engineering

Martin, I; Toso, C; Beltrame, F; Diaspro, A; Fato, M; Facchini, A; Marcacci, M; DePasquale, V; Strocchi, R; Zaffagnini, S. MINERVA BIOTECNOLOGICA. 1997.

Computer-based technique for cell aggregation analysis and cell aggregation in in vitro chondrogenesis.

Martin I; Dozin B; Quarto R; Cancedda R; Beltrame F. CYTOMETRY. 1997.

Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow.

Martin I; Muraglia A; Campanile G; Cancedda R; Quarto R. Endocrinology. 1997.

Producing prefabricated tissues and organs via tissue engineering.

Martin I; Quarto R; Dozin B; Cancedda R. IEEE ENG MED BIOL. 1997.

Regulated expression of fibronectin, laminin and related integrin receptors during the early chondrocyte differentiation.

Tavella S; Bellese G; Castagnola P; Martin I; Piccini D; Doliana R; Colombatti A; Cancedda R; Tacchetti C. Journal of cell science. 1997.

Tissue engineering of cartilage in space.

Freed LE; Langer R; Martin I; Pellis NR; Vunjak-Novakovic G. Proceedings of the National Academy of Sciences of the United States of America. 1997.